DnaK, hsp73, and their molten globules. Two different ways heat shock proteins respond to heat.

THE HEAT-SHOCK PROTEINS

1988 • 5,214 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

Protein structure: A practical approach

1990 • 2,071 citations

Speculations on the functions of the major heat shock and glucose-regulated proteins

1986 • 1,574 citations

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

1988 • 1,504 citations

The molten globule state as a clue for understanding the folding and cooperativity of globular‐protein structure

1989 • 1,446 citations

Interaction of Hsp 70 with Newly Synthesized Proteins: Implications for Protein Folding and Assembly

1990 • 1,293 citations

70K heat shock related proteins stimulate protein translocation into microsomes

1988 • 1,276 citations

Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein

1990 • 1,035 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Immunoglobulin heavy chain binding protein

1983 • 849 citations

‘Molten‐globule state’: a compact form of globular proteins with mobile side‐chains

1983 • 723 citations

α‐lactalbumin: compact state with fluctuating tertiary structure?

1981 • 611 citations

Uncoating ATPase is a member of the 70 kilodalton family of stress proteins

1986 • 607 citations

Is hsp70 the cellular thermometer?

1991 • 586 citations

Acid-induced folding of proteins.

1990 • 555 citations

Protein folding: Hypotheses and experiments

1987 • 544 citations

[3] The preparation of guanidine hydrochloride

1972 • 540 citations

Major heat shock gene of Drosophila and the Escherichia coli heat-inducible dnaK gene are homologous.

1984 • 513 citations

Physical Principles and Techniques of Protein Chemistry

1973 • 500 citations

Hsp70 accelerates the recovery of nucleolar morphology after heat shock.

1984 • 456 citations

The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner

1990 • 407 citations

Conformational states in .beta.-lactamase: molten-globule states at acidic and alkaline pH with high salt

1989 • 404 citations

Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides.

1985 • 365 citations

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

1986 • 354 citations

Interaction of hsp70 with unfolded proteins: effects of temperature and nucleotides on the kinetics of binding.

1991 • 332 citations

Heat capacity and conformation of proteins in the denatured state

1989 • 319 citations

Molten globule intermediates and protein folding

1991 • 281 citations

Stress proteins in biology and medicine

1990 • 273 citations

The dnaK protein of Escherichia coli possesses an ATPase and autophosphorylating activity and is essential in an in vitro DNA replication system.

1983 • 260 citations

The ATPase core of a clathrin uncoating protein.

1987 • 259 citations

Compact state of a protein molecule with pronounced small-scale mobility: bovine ?-lactalbumin

1985 • 257 citations

The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein

1991 • 245 citations

Enzymatic recycling of clathrin from coated vesicles

1986 • 237 citations

Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines.

1987 • 237 citations

DnaK as a thermometer: threonine-199 is site of autophosphorylation and is critical for ATPase activity.

1991 • 218 citations

Use of high-speed size-exclusion chromatography for the study of protein folding and stability

1984 • 169 citations

Constitutively Expressed Rat mRNA Encoding a 70-Kilodalton Heat-Shock-Like Protein

1985 • 164 citations

Mutant p53 proteins bind hsp 72/73 cellular heat shock-related proteins in SV40-transformed monkey cells.

1987 • 162 citations

Refolding and aggregation of bovine carbonic anhydrase B: quasi-elastic light scattering analysis

1990 • 155 citations

Purification and properties of the Escherichia coli dnaK replication protein.

1984 • 144 citations

Renaturation of denatured λ repressor requires heat shock proteins

1990 • 123 citations

Dissociation of clathrin from coated vesicles by the uncoating ATPase.

1990 • 109 citations

Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.

1988 • 106 citations

In Vivo Phosphorus-31 Nuclear Magnetic Resonance Reveals Lowered ATP During Heat Shock of Tetrahymena

1983 • 87 citations

Influence of Ca₂₊ binding on the structure and stability of bovine α‐lactalbumin studied by circular dichroism and nuclear magnetic resonance spectra

1986 • 78 citations

Effects of sulphate and urea on the stability and reversible unfolding of β-lactamase from Staphylococcus aureus

1985 • 76 citations

A member of the Hsp70 family is localized in mitochondria and resembles Escherichia coli DnaK.

1989 • 71 citations

Quasielastic light scattering from human α-lactalbumin: comparison of molecular dimensions in native and ‘molten globule’ states

1986 • 71 citations

Nucleotide Sequence of aBacillus megateriumgene homologous to thednaKgene ofEscherichia coli

1987 • 41 citations

Contribution of disulfide bonds to stability of the folding intermediate of α-lactalbumin

2009 • 30 citations