Contribution of disulfide bonds to stability of the folding intermediate of α-lactalbumin

Tissue sulfhydryl groups

1959 • 25,130 citations

DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

1964 • 18,916 citations

[14]Determination and analysis of urea and guanidine hydrochloride denaturation curves

1986 • 2,265 citations

Dithiothreitol, a New Protective Reagent for SH Groups^*

1964 • 1,933 citations

A thermodynamic approach to the problem of stabilization of globular protein structure: A calorimetric study

1974 • 1,384 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

Ellman's reagent: 5,5′-dithiobis(2-nitrobenzoic acid)—a reexamination

1979 • 997 citations

Helix stabilization by Glu-...Lys+ salt bridges in short peptides of de novo design.

1987 • 930 citations

‘Molten‐globule state’: a compact form of globular proteins with mobile side‐chains

1983 • 723 citations

Tests of the helix dipole model for stabilization of α-helices

1987 • 598 citations

[27] Circular dichroism and optical rotatory dispersion of proteins and polypeptides

1973 • 547 citations

Protein folding: Hypotheses and experiments

1987 • 544 citations

Handbook of Biochemistry and Molecular Biology

2019 • 525 citations

Design of a 4-helix bundle protein: synthesis of peptides which self-associate into a helical protein

1987 • 282 citations

Comparison of the transient folding intermediates in lysozyme and .alpha.-lactalbumin

1985 • 281 citations

Regeneration of Native Secondary and Tertiary Structures by Air Oxidation of Reduced Ribonuclease

1961 • 280 citations

Dipoles of the α-helix and β-sheet: their role in protein folding

1981 • 275 citations

Compact state of a protein molecule with pronounced small-scale mobility: bovine ?-lactalbumin

1985 • 257 citations

Evidence for identity between the equilibrium unfolding intermediate and a transient folding intermediate: a comparative study of the folding reactions of .alpha.-lactalbumin and lysozyme

1986 • 254 citations

Three-state denaturation of α-lactalbumin by guanidine hydrochloride

1976 • 249 citations

Rapid formation of secondary structure framework in protein folding studied by stopped‐flow circular dichroism

1987 • 244 citations

Electrophoretic analysis of the unfolding of proteins by urea

1979 • 241 citations

A helix stop signal in the isolated S-peptide of ribonuclease A

1984 • 189 citations

A folding model of α-lactalbumin deduced from the three-state denaturation mechanism

1977 • 173 citations

Helix-coil stability constants for the naturally occurring amino acids in water. 22. Histidine parameters from random poly[(hydroxybutyl)glutamine-co-L-histidine]

1984 • 162 citations

Inter- and Intramolecular Interactions of α-Lactalbumin. I. The Apparent Heterogeneity at Acid pH^*

1964 • 157 citations

The Role of the Intrachain Disulfide Bond in the Conformation and Stability of the Constant Fragment of the Immunoglobulin Light Chain1

1979 • 137 citations

Direct Spectrophotometric Measurement of the Rate of Reduction of Disulfide Bonds

1973 • 134 citations

Conformations of intermediates in the folding of the pancreatic trypsin inhibitor

1987 • 96 citations

Inter- and Intramolecular Interactions of α-Lactalbumin. II. Aggregation Reactions at Acid pH^*

1964 • 94 citations

The optical activity of the disulfide bond in L-cystine and some derivatives of L-cystine

1968 • 87 citations

A comparison of the physical chemical properties of oxidized and reduced alkylated ribonuclease

1959 • 87 citations

Circular dichroism spectroscopy of bovine pancreatic trypsin inhibitor and five altered conformational states. Relationship of conformation and the refolding pathway of the trypsin inhibitor

1981 • 85 citations

Influence of Ca₂₊ binding on the structure and stability of bovine α‐lactalbumin studied by circular dichroism and nuclear magnetic resonance spectra

1986 • 78 citations

The Isolation and Characterization of the Tryptic, Chymotryptic, Peptic, and Cyanogen Bromide Peptides from Bovine α-Lactalbumin

1970 • 59 citations

Circular dichroism, Raman spectroscopy, and gel filtration of trapped folding intermediates of ribonuclease

1981 • 57 citations

Effects of salts on the nonequivalent stability of the ?-helices of isomeric block copolypeptides

1982 • 55 citations

OXIDIZED RNASE AS A PROTEIN MODEL HAVING NO CONTRIBUTION TO THE HYDROGEN EXCHANGE RATE FROM CONFORMATIONAL RESTRICTIONS

1970 • 42 citations

The kinetics of bovine growth hormone folding are consistent with a framework model.

1987 • 40 citations

Circular dichroism of corticotropin, fragment 1–24, and model compounds. An assessment of the contributions of the peptide chromophore and aromatic residues

1976 • 33 citations

Reoxidation of reduced bovine growth hormone from a stable secondary structure

1986 • 33 citations

Intramolecular perturbation of tryptophans induced by the protonation of ionizable groups in goat α-lactalbumin

1980 • 24 citations

Inter- and intramolecular interactions of α-lactalbumin V. The effect of amidination on association and aggregation

1965 • 19 citations

Studies on the structure in solution of α-lactalbumin

1972 • 17 citations

Circular dichroism of a model compound of l-cystine residue: bismethylamide

1973 • 17 citations

Domain characteristics of the carboxyl‐terminal fragment 206–316 of thermolysin: pH and ionic strength dependence of conformation

1985 • 14 citations

Kinetic correlations between the disulfide bond reduction and the induced conformational change of proteins

1981 • 9 citations

Effects of structure‐forming solutes on chicken eggwhite lysozyme after reductive cleavage of disulfide bonds

1984 • 7 citations