Conformational states in .beta.-lactamase: molten-globule states at acidic and alkaline pH with high salt

Determination of the secondary structures of proteins by circular dichroism and optical rotatory dispersion

1972 • 1,932 citations

The interaction of a naphthalene dye with apomyoglobin and apohemoglobin

1965 • 1,486 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

The Gross Conformation of Protein-Sodium Dodecyl Sulfate Complexes

1970 • 935 citations

‘Molten‐globule state’: a compact form of globular proteins with mobile side‐chains

1983 • 723 citations

Folding and association of proteins

1987 • 697 citations

Preferential interactions of proteins with salts in concentrated solutions

1982 • 686 citations

α‐lactalbumin: compact state with fluctuating tertiary structure?

1981 • 611 citations

Proteins as Random Coils. I. Intrinsic Viscosities and Sedimentation Coefficients in Concentrated Guanidine Hydrochloride

1967 • 545 citations

Protein folding: Hypotheses and experiments

1987 • 544 citations

On the Conformational Stability of Globular Proteins

1965 • 515 citations

The Mechanism of Irreversible Enzyme Inactivation at 100°C

1985 • 442 citations

Quantitative estimation of protein binding site polarity. Fluorescence of N-arylaminonaphthalenesulfonates

1968 • 417 citations

Bacterial Resistance to β-Lactam Antibiotics: Crystal Structure of β-Lactamase from Staphylococcus aureus PC1 at 2.5 Å Resolution

1987 • 349 citations

Comparison of the transient folding intermediates in lysozyme and .alpha.-lactalbumin

1985 • 281 citations

Compact state of a protein molecule with pronounced small-scale mobility: bovine ?-lactalbumin

1985 • 257 citations

Evidence for identity between the equilibrium unfolding intermediate and a transient folding intermediate: a comparative study of the folding reactions of .alpha.-lactalbumin and lysozyme

1986 • 254 citations

Sequential mechanism of refolding of carbonic anhydrase B

1987 • 199 citations

Participation of the protein ligands in the folding of cytochrome c

1972 • 176 citations

‘Molten‐globule“ state accumulates in carbonic anhydrase folding

1984 • 174 citations

Evidence for Residual Structure in Acid- and Heat-denatured Proteins

1967 • 174 citations

A folding model of α-lactalbumin deduced from the three-state denaturation mechanism

1977 • 173 citations

Tertiary structural similarity between a class A β-lactamase and a penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase

1986 • 134 citations

The mechanism of folding of globular proteins. Equilibria and kinetics of conformational transitions of penicillinase from Staphylococcus aureus involving a state of intermediate conformation

1976 • 108 citations

Stabilization of the globular structure of ferricytochrome c by chloride in acidic solvents

1975 • 80 citations

Effects of sulphate and urea on the stability and reversible unfolding of β-lactamase from Staphylococcus aureus

1985 • 76 citations

β-lactamase I from Bacillus cereus. Structure and site-directed mutagenesis

1987 • 69 citations

Folding of ribonuclease A from a partially disordered conformation. Kinetic study under folding conditions

1982 • 65 citations

Conformation of a stable intermediate on the folding pathway of Staphylococcus aureus penicillinase

1978 • 62 citations

Single amino acid mutations block a late step in the folding of β-lactamase from Staphylococcus aureus

1985 • 62 citations

Unfolding and refolding of Staphylococcus aureus penicillinase by urea-gradient electrophoresis

1980 • 61 citations

The mechanism of folding of globular proteins. Suitability of a penicillinase from Staphylococcus Aureus as a model for refolding studies

1976 • 59 citations

Acid unfolding and self-association of recombinant Escherichia coli derived human interferon .gamma.

1987 • 54 citations

Regeneration of RNase A from the reduced protein: models of regeneration pathways.

1982 • 44 citations

Noncooperative temperature melting of a globular protein without specific tertiary structure: Acid form of bovine carbonic anhydrase B

1985 • 32 citations