Flow cytometric detection of total and serine 473 phosphorylated Akt

Cellular survival: a play in three Akts

1999 • 4,229 citations

The protein kinase B/Akt signalling pathway in human malignancy

2002 • 1,609 citations

The PI3K–PDK1 connection: more than just a road to PKB

2000 • 1,563 citations

Synthesis and Function of 3-Phosphorylated Inositol Lipids

2001 • 1,527 citations

Ten years of protein kinase B signalling: a hard Akt to follow

2001 • 1,159 citations

PKB/Akt

2001 • 1,066 citations

AKT/PKB and Other D3 Phosphoinositide-Regulated Kinases: Kinase Activation by Phosphoinositide-Dependent Phosphorylation

1999 • 997 citations

AKT plays a central role in tumorigenesis

2001 • 932 citations

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation.

2001 • 883 citations

Signaling by Distinct Classes of Phosphoinositide 3-Kinases

1999 • 861 citations

Phosphoinositide 3-kinase signalling pathways

2006 • 443 citations

XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells.

2001 • 330 citations

Apoptosis and cancer chemotherapy

2000 • 221 citations

Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis.

2000 • 216 citations

Apoptosis in cancer: cause and cure

2000 • 207 citations

Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry

2002 • 201 citations

Dopamine depletion and subsequent treatment with <scp>l</scp>‐DOPA, but not the long‐lived dopamine agonist pergolide, enhances activity of the Akt pathway in the rat striatum

2007 • 121 citations

Translocation of Akt/PKB to the nucleus of osteoblast‐like MC3T3‐E1 cells exposed to proliferative growth factors

2000 • 117 citations

Update on the biology of chronic lymphocytic leukemia

2000 • 92 citations

Interleukin-11 induces Th2 polarization of human CD4+ T cells

2001 • 92 citations

Growth factor signaling in cell survival: implications for cancer treatment.

2001 • 90 citations

Molecular Abnormalities in Chronic Myeloid Leukemia: Deregulation of Cell Growth and Apoptosis

2000 • 78 citations

Molecular signals in anti-apoptotic survival pathways

2001 • 69 citations

Signaling pathways in apoptosis as potential targets for cancer therapy

2001 • 68 citations

Nerve growth factor promotes activation of the α, β and γ isoforms of protein kinase B in PC12 pheochromocytoma cells

1998 • 62 citations

Bcl-2 Expression in Acute Myeloblastic Leukaemia: Relationship with Autonomous Growth and CD34 Antigen Expression

1997 • 40 citations

The Lymphoid Leukaemias

1990 • 37 citations

The pro-apoptotic drug camptothecin stimulates phospholipase D activity and diacylglycerol production in the nucleus of HL-60 human promyelocytic leukemia cells.

1999 • 25 citations

Biochemical and morphological characterization of the nuclear matrix from apoptotic HL-60 cells

1999 • 24 citations

Bcl-2 family proteins and leukemia. Minireview.

1998 • 22 citations

Etiopathogeny, prognosis and therapy of myelodysplastic syndromes

1997 • 18 citations

Interleukin-11 induces proliferation of human T-cells and its activity is associated with downregulation of p27(kip1).

2002 • 17 citations

PROGNOSTIC FACTORS FOR HEMATOLOGIC CANCERS

2000 • 15 citations

Measurement of proliferation activities in human tumor models: A comparison of flow cytometric methods

1998 • 13 citations

Measurement of proliferation activities in human tumor models: A comparison of flow cytometric methods

1998 • 11 citations

Biochemical and morphological changes in the nuclear matrix prepared from apoptotic HL-60 cells: Effect of different stabilizing procedures

1999 • 11 citations

Potential diagnostic, prognostic and therapeutic implications of some new regulatory proteins in hematologic malignancies.

2000 • 2 citations