Deficient In Vitro and In Vivo Phagocytosis of Apoptotic T Cells by Resident Murine Alveolar Macrophages

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1998 • 7,541 citations

A novel assay for apoptosis Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1995 • 5,208 citations

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

1992 • 3,279 citations

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

1998 • 3,085 citations

A receptor for phosphatidylserine-specific clearance of apoptotic cells

2000 • 1,480 citations

T-cell apoptosis detected in situ during positive and negative selection in the thymus

1994 • 1,071 citations

Phagocyte recognition of cells undergoing apoptosis

1993 • 1,000 citations

MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment

1999 • 973 citations

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

1990 • 871 citations

Lung biology in health and disease

1977 • 770 citations

The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

1998 • 724 citations

Human CD14 mediates recognition and phagocytosis of apoptotic cells

1998 • 685 citations

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus.

1993 • 637 citations

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells.

1992 • 605 citations

Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages.

1993 • 540 citations

Macrophage recognition of cells undergoing programmed cell death (apoptosis).

1985 • 460 citations

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages

2000 • 452 citations

Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice.

1989 • 433 citations

Origin, Kinetics, and characteristics of pulmonary macrophages in the normal steady state.

1979 • 363 citations

Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo.

1995 • 359 citations

Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages.

1982 • 326 citations

Exposure of phosphatidylserine is a general feature in the phagocytosis of apoptotic lymphocytes by macrophages

1999 • 208 citations

The apoptosis-1/Fas protein in human systemic lupus erythematosus.

1994 • 200 citations

Macrophage Recognition of ICAM-3 on Apoptotic Leukocytes

1999 • 183 citations

Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis.

1995 • 168 citations

Biased accumulation of T lymphocytes with "memory"-type CD45 leukocyte common antigen gene expression on the epithelial surface of the human lung.

1990 • 159 citations

Self-Renewal of Pulmonary Alveolar Macrophages: Evidence From Radiation Chimera Studies

1987 • 149 citations

Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells.

1993 • 140 citations

Multiple systems for recognition of apoptotic lymphocytes by macrophages.

1997 • 133 citations

Lymphocyte apoptosis during the silencing of the immune response to acute viral infections in normal, lpr, and Bcl-2-transgenic mice.

1995 • 116 citations

Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes.

1990 • 112 citations

The spontaneous apoptotic cell death of normal human lymphocytes in vitro: The release of, and immunoproliferative response to, nucleosomes in vitro

1991 • 108 citations

Human alveolar macrophages: HLA-DR-positive macrophages that are poor stimulators of a primary mixed leukocyte reaction.

1986 • 108 citations

Alveolar macrophages from humans and rodents selectively inhibit T-cell proliferation but permit T-cell activation and cytokine secretion.

1995 • 85 citations

Simultaneous flow cytometric method to measure phagocytosis and oxidative products by neutrophils

1991 • 83 citations

Different patterns of arachidonate metabolism in autologous human blood monocytes and alveolar macrophages.

1989 • 80 citations

Enhanced 5-lipoxygenase activity in lung macrophages compared to monocytes from normal subjects.

1987 • 79 citations

The specific recognition by macrophages of CD8+,CD45RO+ T cells undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections.

1994 • 77 citations

Previous Uptake of Apoptotic Neutrophils or Ligation of Integrin Receptors Downmodulates the Ability of Macrophages to Ingest Apoptotic Neutrophils

1999 • 72 citations

Interleukin-8 Gene Expression from Human Alveolar Macrophages: The Role of Adherence

1991 • 69 citations

Maintenance of the normal rat alveolar macrophage cell population. The roles of monocyte influx and alveolar macrophage proliferation in situ.

1987 • 69 citations

Lung macrophages and dendritic cells in health and disease

1997 • 62 citations

Evidence of a Selective Major Vascular Marginal Pool of Lymphocytes in the Lung

1987 • 58 citations

Characterization of Bronchoalveolar Lymphocytes during a Specific Antibody-forming Cell Response in the Lungs of Mice

1989 • 55 citations

Class A scavenger receptors and the phagocytosis of apoptotic cells

1999 • 54 citations

Lung lymphocyte elimination by apoptosis in the murine response to intratracheal particulate antigen.

1997 • 54 citations

Elimination of Neutrophils by Apoptosis During the Resolution of Acute Pulmonary Inflammation in Rats

1998 • 49 citations

A novel beta 1 integrin-dependent mechanism of leukocyte adherence to apoptotic cells.

1999 • 48 citations

An assay for the quantitative measurement of in vitro phagocytosis of early apoptotic thymocytes by murine resident peritoneal macrophages

1999 • 48 citations

A Novel β1 Integrin-Dependent Mechanism of Leukocyte Adherence to Apoptotic Cells

1999 • 41 citations

Mechanisms for Recognition and Phagocytosis of Apoptotic Lymphocytes by Macrophages

1996 • 40 citations

Acquisition of peroxidase activity by rat alveolar macrophages during pulmonary inflammation.

1987 • 35 citations

Adhesion receptor phenotypes of murine lung CD4+ T cells during the pulmonary immune response to sheep erythrocytes.

1995 • 33 citations

Selective attrition of non-recirculating T cells during normal passage through the lung vascular bed.

1990 • 29 citations

Lung Lymphocytes Proliferate Minimally in the Murine Pulmonary Immune Response to Intratracheal Sheep Erythrocytes

1998 • 28 citations

Pulmonary T helper lymphocytes are CD44hi, CD45RB- effector/memory cells in mice vaccinated with attenuated cercariae of Schistosoma mansoni.

1993 • 23 citations

Functional analysis of human bronchial mucosal T cells extracted with interleukin-2.

1994 • 17 citations

Expression of la by Murine Alveolar Macrophages Is Upregulated during the Evolution of a Specific Immune Response in Pulmonary Parenchyma

1988 • 15 citations

Whither goes the alveolar macrophage? Another small chapter is written on the localized response of this crucial cell

1998 • 9 citations

Novel Cell Surface Antigens Expressed on Mouse Alveolar Macrophages

1991 • 4 citations

Close Localization of Mouse CD14 and CD32/16 in the Cell Surface of Monocytic Cell Lines

1999 • 3 citations