Previous Uptake of Apoptotic Neutrophils or Ligation of Integrin Receptors Downmodulates the Ability of Macrophages to Ingest Apoptotic Neutrophils

Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages.

1992 • 3,279 citations

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF.

1998 • 3,085 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

1989 • 1,540 citations

Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis

1990 • 871 citations

Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis.

1992 • 818 citations

Human CD14 mediates recognition and phagocytosis of apoptotic cells

1998 • 685 citations

Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells.

1992 • 605 citations

Macrophage recognition of cells undergoing programmed cell death (apoptosis).

1985 • 460 citations

Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.

1996 • 427 citations

In vivo fate of the inflammatory macrophage during the resolution of inflammation: inflammatory macrophages do not die locally, but emigrate to the draining lymph nodes.

1996 • 381 citations

Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein

1996 • 380 citations

Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism.

1989 • 298 citations

Recognition of oxidatively damaged and apoptotic cells by an oxidized low density lipoprotein receptor on mouse peritoneal macrophages: role of membrane phosphatidylserine.

1995 • 293 citations

Phagocytosis of apoptotic neutrophils does not induce macrophage release of thromboxane B2

1992 • 284 citations

Complementation of dominant suppression implicates CD98 in integrin activation

1997 • 282 citations

Studies in listeriosis show the strong symbiosis between the innate cellular system and the T‐cell response

1997 • 270 citations

Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1.

1994 • 247 citations

The glomerular response to injury: Progression or resolution?

1994 • 230 citations

Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis.

1984 • 207 citations

Trans-dominant inhibition of integrin function.

1996 • 174 citations

Proinflammatory cytokines potentiate thrombospondin-mediated phagocytosis of neutrophils undergoing apoptosis.

1995 • 168 citations

Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis

1992 • 163 citations

CD44 regulates phagocytosis of apoptotic neutrophil granulocytes, but not apoptotic lymphocytes, by human macrophages.

1997 • 150 citations

Regulation of Macrophage Phagocytosis of Apoptotic Cells by cAMP

1998 • 149 citations

Mutation of the Cytoplasmic Domain of the Integrin β3 Subunit

1995 • 144 citations

Particle digestibility is required for induction of the phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells.

1993 • 140 citations

Multiple systems for recognition of apoptotic lymphocytes by macrophages.

1997 • 133 citations

Recognition of apoptotic cells by human macrophages: inhibition by a monocyte/macrophage‐specific monoclonal antibody

1994 • 118 citations

Integrin beta 3 cytoplasmic tail is necessary and sufficient for regulation of alpha 5 beta 1 phagocytosis by alpha v beta 3 and integrin-associated protein.

1995 • 115 citations

Ligation of CD69 induces apoptosis and cell death in human eosinophils cultured with granulocyte-macrophage colony-stimulating factor

1996 • 103 citations

Functional switching of macrophage responses to tumor necrosis factor-alpha (TNF alpha) by interferons. Implications for the pleiotropic activities of TNF alpha.

1994 • 99 citations

Integrin receptor-mediated mobilisation of intranuclear calcium in rat osteoclasts

1993 • 98 citations

Integrins on rat osteoclasts: Characterization of two monoclonal antibodies (F4 and F11) to rat β3

1992 • 85 citations

Transforming growth factor-beta primes macrophages to express inflammatory gene products in response to particulate stimuli by an autocrine/paracrine mechanism.

1993 • 60 citations

Interleukin-4 ameliorates experimental glomerulonephritis and up-regulates glomerular gene expression of IL-1 decoy receptor

1997 • 46 citations

Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production.

1998 • 39 citations

Modulation of Macrophage Maturation by Cytokines and Lipid Mediators: A Potential Role in Resolution of Pulmonary Inflammationa

1994 • 39 citations

Involvement of the IL-2 Receptor γ-Chain (γc) in the Control by IL-4 of Human Monocyte and Macrophage Proinflammatory Mediator Production

1998 • 30 citations