Methylation of DNA in Prokaryotes

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Escherichia Coli and Salmonella: Typhimurium Cellular and Molecular Biology

1987 • 4,385 citations

Escherichia coli and Salmonella typhimurium: Cellular and molecular biology

1988 • 3,957 citations

A complementation analysis of the restriction and modification of DNA in Escherichia coli

1969 • 3,866 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

On the Regulation of DNA Replication in Bacteria

1963 • 1,441 citations

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants.

1990 • 1,149 citations

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

1988 • 891 citations

Quantitative evaluation ofEscherichia colihost strains for tolerance to cytosine methylation in plasmid and phage recombinants

1989 • 744 citations

Heat-induced deamination of cytosine residues in deoxyribonucleic acid

1974 • 725 citations

RESTRICTION AND MODIFICATION SYSTEMS

1991 • 702 citations

DNA Modification and Restriction

1969 • 624 citations

A structural taxonomy of DNA-binding domains

1991 • 615 citations

An N -Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues

1974 • 582 citations

DNA Mismatch Correction in a Defined System

1989 • 551 citations

Predictive motifs derived from cytosine methyltransferases

1989 • 505 citations

HOST CONTROLLED VARIATION IN BACTERIAL VIRUSES

1953 • 481 citations

An invertible element of DNA controls phase variation of type 1 fimbriae of Escherichia coli.

1985 • 479 citations

Sequence diversity among related genes for recognition of specific targets in DNA molecules

1983 • 478 citations

Different base/base mismatches are corrected with different efficiencies by the methyl-directed DNA mismatch-repair system of E. coli

1984 • 468 citations

E. coli oriC and the dnaA gene promoter are sequestered from dam methyltransferase following the passage of the chromosomal replication fork

1990 • 464 citations

A Suggested nomenclature for bacterial host modification and restriction systems and their enzymes

1973 • 457 citations

A model for initiation at origins of DNA replication

1988 • 452 citations

Substrate and sequence specificity of a eukaryotic DNA methylase

1982 • 441 citations

DNA MISMATCH CORRECTION

1987 • 427 citations

OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins.

1989 • 415 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs

1983 • 404 citations

Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.

1980 • 391 citations

A NONHEREDITARY, HOST-INDUCED VARIATION OF BACTERIAL VIRUSES

1952 • 390 citations

Timing of initiation of chromosome replication in individual Escherichia coli cells.

1986 • 389 citations

Isolation of Deoxyribonucleic Acid Methylase Mutants of Escherichia coli K-12

1973 • 372 citations

Complementary specificity of restriction endonucleases of Diplococcus pneumoniae with respect to DNA methylation

1977 • 369 citations

Two DNA methyltransferases from murine erythroleukemia cells: purification, sequence specificity, and mode of interaction with DNA.

1983 • 361 citations

Methyl-directed repair of DNA base-pair mismatches in vitro.

1983 • 344 citations

IS10 transposition is regulated by DNA adenine methylation

1985 • 341 citations

Recognition sequence of the dam methylase of Escherichia coli K12 and mode of cleavage of Dpn I endonuclease.

1979 • 339 citations

McrA and McrB restriction phenotypes of someE.colistrains and implications for gene cloning

1988 • 337 citations

Atomic Structure of Thymidylate Synthase: Target for Rational Drug Design

1987 • 329 citations

Escherichia coli K-12 restricts DNA containing 5-methylcytosine.

1986 • 325 citations

The replicative origin of the E. coli chromosome binds to cell membranes only when hemimethylated

1988 • 311 citations

Repair tracts in mismatched DNA heteroduplexes.

1976 • 300 citations

Methyl-directed DNA Mismatch Correction

1989 • 297 citations

EFFECTS OF HIGH LEVELS OF DNA ADENINE METHYLATION ON METHYL-DIRECTED MISMATCH REPAIR IN ESCHERICHIA COLI

1983 • 294 citations

Restriction enzymes and their isoschizomers

1990 • 271 citations

Bacteriophage P1 cloning system for the isolation, amplification, and recovery of DNA fragments as large as 100 kilobase pairs.

1990 • 270 citations

Bacteriophage survival: multiple mechanisms for avoiding the deoxyribonucleic acid restriction systems of their hosts

1983 • 262 citations

The construction in vitro of transducing derivatives of phage lambda

1976 • 258 citations

Sequence of the D-aspartyl/L-isoaspartyl protein methyltransferase from human erythrocytes

1989 • 254 citations

MISMATCH REPAIR IN ESCHERICHIA COLI

1986 • 253 citations

Heteroduplex deoxyribonucleic acid base mismatch repair in bacteria

1986 • 252 citations

Class-IIS restriction enzymes — a review

1991 • 250 citations

Direct identification of the active-site nucleophile in a DNA (cytosine-5)-methyltransferase

1991 • 246 citations

Organization of restriction-modification systems

1991 • 241 citations

Biological function for 6-methyladenine residues in the DNA of Escherichia coli K12

1974 • 232 citations

Cytosine-specific type II DNA methyltransferases

1989 • 230 citations

Hemimethylation prevents DNA replication in E. coli

1987 • 227 citations

DNA mismatch-repair in Escherichia coli counteracting the hydrolytic deamination of 5-methyl-cytosine residues.

1987 • 224 citations

Nucleotide sequence of the origin of replication of the Escherichia coli K-12 chromosome.

1979 • 224 citations

McrBC: a multisubunit GTP-dependent restriction endonuclease

1992 • 224 citations

Isolation and characterization of the Escherichia coli mutH gene product.

1987 • 220 citations

Cloning, characterization, and expression inEscherichia coliof the gene coding for the CpG DNA methylase fromSpiroplasma sp.strain MQ1(M Sssl)

1990 • 214 citations

Location of DNA methylation genes on the Escherichia coli K-12 genetic map

1973 • 211 citations

Finding sequence motifs in groups of functionally related proteins.

1990 • 208 citations

P1 plasmid replication: Replicon structure

1984 • 207 citations

The great GATC: DNA methylation in E. coli

1989 • 203 citations

Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair.

1988 • 203 citations

EcoRI methylase. Physical and catalytic properties of the homogeneous enzyme.

1977 • 202 citations

Structure and Mechanism of Multifunctional Restriction Endonucleases

1981 • 201 citations

Induced mutagenesis in dam − mutants of Escherichia coli: A role for 6-methyladenine residues in mutation avoidance

1978 • 198 citations

Replication origin of the Escherichia coli K-12 chromosome: The size and structure of the minimum DNA segment carrying the information for autonomous replication

1980 • 197 citations

Sequence analysis of the DNA encoding the Eco RI endonuclease and methylase.

1981 • 194 citations

WORKSHOP SUMMARY: Regulation of Plasmid Replication

1980 • 193 citations

Regulation of pap pilin phase variation by a mechanism involving differential dam methylation states.

1990 • 192 citations

A deoxyribonuclease of Diplococcus pneumoniae specific for methylated DNA

1975 • 192 citations

Phase variation in Salmonella: genetic analysis of a recombinational switch.

1979 • 190 citations

Pleiotropic effects of a DNA adenine methylation mutation (dam-3) in Escherichia coli K12

1975 • 183 citations

Sequence specificity of the P1 modification methylase (M·Eco P1) and the DNA methylase (M·Eco dam) controlled by the Escherichia coli dam gene

1978 • 181 citations

The role of dam methyltransferase in the control of DNA replication in E. coli

1990 • 179 citations

Timing and targeting: The biological functions of Dam methylation in E. coli

1988 • 178 citations

The Isolation and Characterization of theEsherichia ColiDNA adenine methylase(dam)gene

1983 • 177 citations

Transcriptional activation of a pap pilus virulence operon from uropathogenic Escherichia coli.

1985 • 175 citations

DNA cytosine methylation and heat-induced deamination

1986 • 174 citations

Bacteriophage P1 cre gene and its regulatory region

1986 • 171 citations

Site-specific methylases induce the SOS DNA repair response in Escherichia coli

1987 • 169 citations

DNA sequences of structural genes for Eco RI DNA restriction and modification enzymes.

1981 • 167 citations

Physical mapping of BglII, BamHI, EcoRI, HindIII and PstI Restriction fragments of bacteriophage P1 DNA

1977 • 163 citations

Characterization of a unique methyl-specific restriction system in Streptomyces avermitilis

1988 • 163 citations

Escherichia coli mutants uvr D and uvr E deficient in gene conversion of λ-heteroduplexes

1975 • 154 citations

Effect of dam methylation on the activity of the E. coli replication origin, oriC.

1985 • 154 citations

Type III restriction enzymes need two inversely oriented recognition sites for DNA cleavage

1992 • 153 citations

Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases

1989 • 152 citations

Effects of methylation on the stability of nucleic acid conformations. Studies at the polymer level.

1978 • 150 citations

A family of regulatory genes associated with type II restriction-modification systems

1991 • 150 citations

Replication of a bacterial plasmid and an episome in Escherichia coli

1970 • 146 citations

Cloning of a restriction-modification system from Proteus vulgaris and its use in analyzing a methylase-sensitive phenotype in Escherichia coli

1985 • 141 citations

Identification of base mismatches recognized by the heteroduplex-DNA-repair system of Streptococcus pneumoniae

1982 • 141 citations

Model for how type I restriction enzymes select cleavage sites in DNA.

1988 • 138 citations

Nudeotide sequence of the BsuRI restriction-modification system

1985 • 135 citations

Characterization of the genes coding for theEcoRV restriction and modification system ofEscherichia coli

1984 • 135 citations

The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease

1991 • 135 citations

Importance of state of methylation of oriC GATC sites in initiation of DNA replication in Escherichia coli.

1985 • 134 citations

Structure and function of restriction endonucleases

1991 • 132 citations

The hsd (host specificity) genes of E. coli K12

1980 • 130 citations

Escherichia coli dam methylase. Physical and catalytic properties of the homogeneous enzyme.

1982 • 129 citations

In vivo genetic exchange of a functional domain from a type II A methylase between lactococcal plasmid pTR2030 and a virulent bacteriophage

1991 • 127 citations

DNA METHYLATION IN ESCHERICHIA COLI

1987 • 127 citations

DNA sequence organization of IS 10 -right of Tn 10 and comparison with IS 10 -left

1982 • 126 citations

Restriction of nonglucosylated T-even bacteriophage: Properties of permissive mutants of Escherichia coli B and K12

1967 • 125 citations

Specific mismatch correction in bacteriophage lambda crosses by very short patch repair

1983 • 125 citations

Regulation of plasmid replication.

1984 • 123 citations

Bromouracil mutagenesis and mismatch repair in mutator strains of Escherichia coli

1978 • 121 citations

Characterization and expression of the Escherichia coli Mrr restriction system

1991 • 121 citations

Genetic basis of the complementary Dpnl and Dpnll restriction systems of S. pneumoniae: An intercellular cassette mechanism

1986 • 121 citations

Bacteriophage survival: multiple mechanisms for avoiding the deoxyribonucleic acid restriction systems of their hosts.

1983 • 119 citations

Identification of a novel genetic element in Escherichia coli K-12

1980 • 118 citations

Phase-variation of pyelonephritis-associated pili in Escherichia coli: evidence for transcriptional regulation.

1989 • 118 citations

Genetic and physical mapping of the mcrA (rglA) and mcrB (rglB) loci of Escherichia coli K-12.

1989 • 117 citations

The leucine-Lrp regulon in E. coli: A global response in search of a raison d'Être

1992 • 117 citations

Bacterial genes mutL, mutS, and dcm participate in repair of mismatches at 5-methylcytosine sites

1987 • 117 citations

Sequential order of target-recognizing domains in multispecific DNA-methyltransferases.

1988 • 116 citations

Effect of dam methylation on Tn5 transposition

1988 • 116 citations

Organization and function of the mcrBC genes of Escherichia coli K‐12

1992 • 116 citations

Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.

1981 • 114 citations

Evolution of type II DNA methyltransferases

1989 • 110 citations

Requirement for d(GATC) sequences in Escherichia coli mutHLS mismatch correction.

1987 • 109 citations

Repair of DNA Base-pair Mismatches in Extracts of Escherichia coli

1984 • 109 citations

The sequence specificity domain of cytosine-C5 methylases

1991 • 108 citations

A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene

1990 • 108 citations

Nucleotide sequence and expression of the gene encoding theEcoRII modification enzyme

1987 • 106 citations

Characterization of DNA adenine methylation mutants of Escherichia coli K12

1979 • 103 citations

Basis for changes in DNA recognition by the Type I DNA restriction and modification enzymes

1989 • 103 citations

Procaryotic and eucaryotic traits of DNA methylation in spiroplasmas (mycoplasmas)

1985 • 102 citations

GATC sequences, DNA nicks and the MutH function in Escherichia coli mismatch repair.

1987 • 101 citations

Replication of the prophage P1 during the cell cycle of Escherichia coli

1977 • 100 citations

Genetic and sequence organization of the mcrBC locus of Escherichia coli K-12

1990 • 99 citations

DNA adenine methylation of GATC sequences appeared recently in the Escherichia coli lineage

1984 • 97 citations

Reassortment of DNA recognition domains and the evolution of new specificities

1987 • 97 citations

Construction and use of chimeric SPR/phi 3T DNA methyltransferases in the definition of sequence recognizing enzyme regions.

1987 • 96 citations

The DNA modification function of temperate phage Mu-1

1976 • 95 citations

Type III DNA restriction and modification systems EcoP1 and EcoP15

1988 • 95 citations

Site-specific methylation: effect on DNA modification methyltransferases and restriction endonucleases

1991 • 94 citations

Quantitation of Dam methyltransferase in Escherichia coli

1992 • 93 citations

Electron microscopic analysis of bacteriophages P1, P1Cm, and P7

1977 • 92 citations

Genetic recombination can generate altered restriction specificity.

1984 • 90 citations

Cloning, sequencing and expression of theTaqI restriction-modification system

1987 • 89 citations

Efficient transformation of Bacillus thuringiensis requires nonmethylated plasmid DNA

1991 • 89 citations

Methylation and cleavage sequences of the EcoP1 restriction-modification enzyme

1979 • 89 citations

Mismatch repair of deaminated 5-methyl-cytosine

1987 • 88 citations

The E. coli uvrD gene product is DNA helicase II

1983 • 88 citations

Spontaneous mutagenesis in Escherichia coli strains lacking 6-methyladenine residues in their DNA an altered mutational spectrum in dam− mutants

1979 • 88 citations

Hyper-recombination in dam mutants of Escherichia coli K-12

1976 • 88 citations

Nucleotide sequence of the FokI restriction-modification system: separate strand-specificity domains in the methyltransferase

1989 • 86 citations

Identification of the uvrD gene product of Escherichia coli as DNA helicase II and its induction by DNA-damaging agents.

1984 • 86 citations

The E. coli cell surface specifically prevents the initiation of DNA replication at oriC on heminethylated DNA templates

1990 • 85 citations

Isolation and characterization of dam+ revertants and suppressor mutations that modify secondary phenotypes of dam-3 strains of Escherichia coli K-12

1980 • 85 citations

Organization and sequence of the hsd genes of Escherichia coli K-12

1987 • 85 citations

Genetic analysis of the phase variation control of expression of type 1 fimbriae in Escherichia coli

1985 • 84 citations

Allosteric and catalytic binding of S-adenosylmethionine to Escherichia coli DNA adenine methyltransferase monitored by 3H NMR.

1991 • 83 citations

VERY SHORT PATCH MISMATCH REPAIR IN PHAGE LAMBDA: REPAIR SITES AND LENGTH OF REPAIR TRACTS

1986 • 83 citations

Evidence for a methylation-blocking factor (mbf) locus involved in pap pilus expression and phase variation in Escherichia coli

1991 • 83 citations

Cytosine-specific DNA modification interferes with plasmid establishment in Escherichia coli K12: Involvement of rglB

1986 • 82 citations

Methylation of GATC sites is required for precise timing between rounds of DNA replication in Escherichia coli

1989 • 82 citations

The bacterial origin of replication, oriC

1986 • 80 citations

The nucleotide sequence of the HhaII restriction and modification genes from Haemophilus haemolyticus

1983 • 80 citations

Nucleotide sequence of the Dpn II DNA methylase gene of Streptococcus pneumoniae and its relationship to the dam gene of Escherichia coli.

1985 • 80 citations

Structural homologies among type I restriction-modification systems.

1982 • 80 citations

P1 plasmid replication. Purification and DNA-binding activity of the replication protein RepA.

1986 • 79 citations

Genetics of host-controlled restriction and modification inEscherichia coli

1969 • 79 citations

Proteins encoded by the DpnII restriction gene cassette

1987 • 79 citations

The Escherichia coli regulatory protein OxyR discriminates between methylated and unmethylated states of the phage Mu mom promoter.

1989 • 78 citations

Viability of Escherichia coli K-12 DNA adenine methylase (dam) mutants requires increased expression of specific genes in the SOS regulon

1985 • 77 citations

Recombination in the λ repressor gene: evidence that very short patch (VSP) mismatch correction restores a specific sequence

1985 • 76 citations

Organization of multispecific DNA methyltransferases encoded by temperate Bacillus subtilis phages.

1987 • 74 citations

A hybrid recognition sequence in a recombinant restriction enzyme and the evolution of DNA sequence specificity

1985 • 74 citations

The organization and complete nucleotide sequence of the PstI restriction-modification system.

1984 • 74 citations

Two DNA recognition domains of the specificity polypeptides of a family of type I restriction enzymes.

1986 • 74 citations

The GATATC‐modification enzyme EcoRV is closely related to the GATC‐recognizing methyltransferases DpnII and dam from E. coli and phage T₄

1987 • 73 citations

Purification and characterization of the unusual deoxynucleoside, alpha-N-(9-beta-D-2'-deoxyribofuranosylpurin-6-yl)glycinamide, specified by the phage Mu modification function.

1983 • 73 citations

Cleavage of the bacteriophage P1 packaging site (pac) is regulated by adenine methylation.

1990 • 73 citations

Structure and function of restriction endonucleases

1992 • 73 citations

Chimeric multispecific DNA methyltransferases with novel combinations of target recognition

1988 • 72 citations

Conservation of complex DNA recognition domains between families of restriction enzymes

1989 • 71 citations

DNA recognition and cleavage by the EcoP15 restriction endonuclease

1979 • 71 citations

Regulation of a new bacteriophage T4 gene, 69, that spans an origin of DNA replication.

1984 • 71 citations

DNA restriction-modification enzymes of phage P1 and plasmid p15B

1983 • 69 citations

A novel activity in Escherichia coli K-12 that directs restriction of DNA modified at CG dinucleotides

1991 • 69 citations

Characterization of the cloned BamHI restriction modification system: its nucleotide sequence, properties of the methylase, and expression in heterologous hosts

1991 • 69 citations

DNA methyltransferase genes of Bacillus subtilis phages: comparison of their nucleotide sequences

1986 • 69 citations

In vivo methylation by Escherichia coli K-12 mec+ deoxyribonucleic acid-cytosine methylase protects against in vitro cleavage by the RII restriction endonuclease (R. Eco RII)

1976 • 68 citations

Restriction and modification in Bacillus subtilis: nucleotide sequence, functional organization and product of the DNA methyltransferase gene of bacteriophage SPR

1984 • 67 citations

Cloning and expression of the Pst I restriction-modification system in Escherichia coli.

1981 • 66 citations

The FokI Restriction-Modification System

1989 • 66 citations

Enhanced recovery and restriction mapping of DNA fragments cloned in a new λ vector

1988 • 65 citations

DNA restriction and modification systems in Salmonella

1974 • 65 citations

Purification and Properties of a New Restriction Endonuclease from Haemophilus influenzae Rf

1978 • 65 citations

Timing of chromosomal replication in Escherichia coli

1988 • 64 citations

The double role of methyl donor and allosteric effector of S-adenosyl-methionine for Dam methylase of E. coli

1990 • 64 citations

Alterations in DNA helix stability due to base modifications can be evaluated using denaturing gradient gel electrophoresis

1987 • 64 citations

Mutational analysis of insertion sequence 50 (IS50) and transposon 5 (Tn5) ends.

1988 • 63 citations

Multiple steps in DNA recognition by restriction endonuclease from E. coli K

1975 • 63 citations

GATC sequence and mismatch repair in Escherichia coli.

1986 • 63 citations

On the mechanism of DNA-adenine methylase.

1988 • 62 citations

Substitutions of a cysteine conserved among DNA cytosine methylases result in a variety of phenotypes

1992 • 62 citations

DpnA, a methylase for single-strand DNA in the Dpn II restriction system, and its biological function.

1989 • 62 citations

Recognition and cleavage of the bacteriophage P1 packaging site (pac)

1987 • 61 citations

Conservation of organization in the specificity polypeptides of two families of type I restriction enzymes

1989 • 61 citations

Recognition and cleavage of the bacteriophage P1 packaging site (pac)

1987 • 60 citations

Molecular cloning of a functional dam+ gene coding for phage T4 DNA adenine methylase

1983 • 59 citations

N-Methyl-N′-nitro-N-nitrosoguanidine sensitivity of E. coli mutants deficient in DNA methylation and mismatch repair

1981 • 59 citations

Involvement of Escherichia coli Mismatch Repair in DNA Replication and Recombination

1984 • 59 citations

ATP-induced conformational changes in the restriction endonuclease from Escherichia coli K-12.

1978 • 58 citations

DNA methyltransferase-dependent transcription of the phage Mu mom gene.

1982 • 58 citations

Methylation of Prokaryotic DNA

1984 • 58 citations

Coordinate initiation of chromosome and minichromosome replication in Escherichia coli

1987 • 56 citations

The irreversible binding of azacytosine-containing DNA fragments to bacterial DNA(cytosine-5)methyltransferases.

1985 • 56 citations

Restriction and modification in Bacillus subtilis: DNA methylation potential of the related bacteriophages Z, SPR, SP beta, phi 3T, and rho 11

1983 • 56 citations

Nuclotide sequence of theDdeI restriction-modification system and characterization of the methylase protein

1987 • 56 citations

Expression of the Escherichia coli dam gene

1992 • 55 citations

Mutations the confer de Novo activity upon a maintenance methyltransferase

1991 • 55 citations

Molecular cloning and characterization of the gene encoding the DNA methyltransferase, M.CviBIII, fromChlorellavirus NC-1A

1987 • 54 citations

Cloning and sequencing the HinfI restriction and modification genes

1988 • 53 citations

Structure of the gene coding for the sequence-specific DNA-methyltransferase of theB. subtilisphage SPR

1984 • 53 citations

Agmenellum quadruplicatum M.AquI, a novel modification methylase

1990 • 51 citations

Cloning theBamHI restriction modification system

1989 • 51 citations

A Mu gin complementing function and an invertible DNA region in Escherichia coli K-12 are situated on the genetic element e14

1984 • 50 citations

Methylation Regulates the Expression of a DNA-modification Function Encoded by Bacteriophage Mu

1983 • 50 citations

Molecular cloning and expression in Escherichia coli of two modification methylase genes of Bacillus subtilis

1983 • 49 citations

Cloning and characterization of the genes encoding theMspl restriction modification system

1989 • 49 citations

Cloning and sequencing of genes encoding the TthHB8I restriction and modification enzymes: comparison with the isoschizomeric TaqI enzymes

1992 • 48 citations

TheoriCunwinding bydammethylation inEscherichia coli

1988 • 48 citations

Increased protein flexibility leads to promiscuous protein-DNA interactions in type IC restriction-modification systems.

1991 • 48 citations

The FokI Restriction-Modification System

1989 • 47 citations

Identification of a highly conserved domain in the EcoRII methyltransferase which can be photolabeled with S-adenosyl-L-[methyl-3H]methionine. Evidence for UV-induced transmethylation of cysteine 186.

1991 • 47 citations

The frequency of expression of pyelonephritis‐associated pili is under regulatory control

1987 • 47 citations

Regulation and expression of the bacteriophage Mu mom gene: mapping of the transactivation (Dad) function to the C region

1985 • 47 citations

Purification, cloning and sequence analysis ofRsrIDNA methyltransferase: lack of homology between two enzymes,RsrI andEcoRI, that methylate the same nucleotide in Identical recognition sequences

1989 • 46 citations

Asymmetric repair of bacteriophage T7 heteroduplex DNA

1981 • 46 citations

Selection againstdam methylation sites in the genomes of DNA of enterobacteriophages

1985 • 44 citations

Nucleotide sequence of the McrB region of Escherichia coli K-12 and evidence for two independent translational initiation sites at the mcrB locus

1989 • 44 citations

Genetic requirements for hyper-recombination by very short patch mismatch repair: Involvement ofEscherichia coli DNA polymerase I

1989 • 42 citations

Transformation of restriction endonuclease phenotype in Streptococcus pneumoniae

1982 • 42 citations

Restriction enzymes and their isoschizomers

1991 • 42 citations

Bacterial DNA Modification

1984 • 42 citations

Base methylation and local DNA helix stability

1989 • 41 citations

Role of bacteriophage Mu C protein in activation of the mom gene promoter

1989 • 41 citations

Factors affecting transposition activity of IS50 and Tn5 ends

1989 • 41 citations

Sequence, internal homology and high-level expression of the gene for a DNA-(cytosineN4)-methyltransferase, M-PvuII

1989 • 41 citations

AND REPRESENT A SINGLE GENE

1978 • 41 citations

Mycoplasma restriction: identification of a new type of restriction specificity for DNA containing 5-methylcytosine

1986 • 41 citations

Sequence specificity of the wild-type (dam+) and mutant (damh) forms of bacteriophage T2 DNA adenine methylase

1978 • 40 citations

In vitro replication of a dam methylated and non-methylated ori-C plasmid

1984 • 39 citations

Cloning and characterization of theHpallmethylase gene

1990 • 38 citations

Cloning and analysis of the HaeIII and HaeII methyltransferase genes

1988 • 38 citations

Direct photolabeling of the EcoRII methyltransferase with S-adenosyl-L-methionine.

1990 • 37 citations

The mom gene of bacteriophage Mu: a unique regulatory scheme to control a lethal function

1985 • 37 citations

P1 plasmid replication requires methylated DNA.

1987 • 37 citations

Cloning and characterization of theMbollrestriction-modification system

1991 • 36 citations

A new method for the rapid identification of genes encoding restriction and modification enzymes

1991 • 35 citations

Complexes formed between the restriction endonuclease EcoK and heteroduplex DNA

1981 • 35 citations

The amino acid sequence of the CCGG recognizing DNA methyltransferase M.BsuFI: implications for the analysis of sequence recognition by cytosine DNA methyltransferases.

1990 • 35 citations

Structure and function of restriction endonucleases

1992 • 35 citations

Cloning and structural characterization of the mcrA locus of Escherichia coli

1991 • 35 citations

Binding of the EcoRll methylase to azacytosine-containing DNA

1986 • 34 citations

The HgaI restriction-modification system contains two cytosine methylase genes responsible for modification of different DNA strands

1991 • 33 citations

Cloning and characterization of two tandemly arranged DNA methyltransferase genes of Neisseria lactamica: An adenine-specific M.NlaIII and a cytosine-type methylase

1990 • 33 citations

dam methylation and the initiation of DNA replication on oriC plasmids

1989 • 32 citations

M.EcoPl5 methylates the second adenine in its recognition sequence

1991 • 32 citations

The mom gene of bacteriophage Mu: the mechanism of methylation-dependent expression.

1986 • 32 citations

S1 nuclease mapping of the phage Mu mom gene promoter: a model for the regulation of mom expression

1984 • 32 citations

Transposon mutagenesis and genetic mapping of the rglA and rglB loci of Escherichia coli

1985 • 32 citations

The DNA sequence recognised by the HinfIII restriction endonuclease

1981 • 31 citations

'Pseudo' domains in phage-encoded DNA methyltransferases

1991 • 31 citations

The sequence and mom-transactivation function of the C gene of bacteriophage Mu

1986 • 31 citations

Identification of a second polypeptide required for McrB restriction of 5-methylcytosine-containing DNA in Escherichia coli K12

1989 • 30 citations

Molecular cloning, sequencing, and mapping of the bacteriophage T2 dam gene

1988 • 30 citations

Characterization of the Escherichia coli modified cytosine restriction (mcrB) gene

1987 • 30 citations

Cloning and expression of the MspI restriction and modification genes

1988 • 29 citations

Attachment site of the genetic element e14

1988 • 29 citations

Cloning of methylated transforming DNA from Neurospora crassa in Escherichia coli.

1988 • 29 citations

Identification and characterization of a gene responsible for inhibiting propagation of methylated DNA sequences in mcrA mcrB1 Escherichia coli strains

1991 • 28 citations

Neucleotide sequence of thedcmlocus ofEsherichia coliK12

1989 • 28 citations

Nomenclature relating to restriction of modified DNA in Escherichia coli

1991 • 28 citations

Control of circularization of bacteriophage P1 DNA in Escherichia coli

1981 • 28 citations

[17] Purification and properties of the complementary endonucleases DpnI and DpnII

1980 • 28 citations

Counterselection of GATC sequences in enterobacteriophages by the components of the methyl-directed mismatch repair system

1991 • 27 citations

DNA restriction and modification systems in Salmonella

1975 • 27 citations

Effect of lambda packaging extractmcrrestriction activity on DNA cloning

1989 • 27 citations

Nonrandom minichromosome replication in Escherichia coli K-12

1987 • 27 citations

Characterization of the mcrBC region of Escherichia coli K-12 wild-type and mutant strains

1992 • 27 citations

Factors determining the frequency of plasmid cointegrate formation mediated by insertion sequence IS3 from Escherichia coli

1991 • 26 citations

An anticodon nuclease gene inserted into ahsdregion encoding a type I DNA restriction system

1990 • 26 citations

Critical sequences in the core of the P1 plasmid replication origin

1991 • 26 citations

Cloning, characterization and evolation of theBsuFI restriction endonuclease gene ofBacillus subtilisand purification of the enzyme

1991 • 25 citations

Physical mapping and cloning of bacteriophage T4 anti-restriction endonuclease gene

1982 • 25 citations

The mom Gene of Bacteriophage Mu

1984 • 24 citations

BsuBI—an isospecific restriction and modification system ofPstI: characterization of theBsuBI genes and enzymes

1992 • 24 citations

Primary structure of a DNA (N6-adenine)-methyltransferase from Escherichia coli virus T1. DNA sequence, genomic organization, and comparative analysis.

1990 • 23 citations

M · H2I, a multispecific 5C-DNA methyltransferase encoded by Bacillus amyloliquefaciens phage H2

1991 • 22 citations

Molecular cloning and characterization of the gene encoding the adenine methyltransferase M.CviRI fromChlorellavirus XZ-6E

1991 • 22 citations

Nucleotide sequence analysis and expression of the minimum REPI replication region and incompatibility determinants of pColV-K30

1989 • 22 citations

Characterization of the phage P1 dam gene

1988 • 20 citations

Phage-coded protein prevents restriction of unmodified progeny T4 DNA

1976 • 20 citations

The role of dam methylation in controlling gene expression

1987 • 20 citations

Stepwise cloning and molecular characterization of theHgiDI restriction-modification system fromHerpetosiphon giganteus Hpa2

1991 • 19 citations

Efficient construction of plant genomic libraries requires the use ofmcr host strains and packaging mixes

1990 • 18 citations

Complementation by detached parts of GGCC-specific DNA methyltransferases

1991 • 17 citations

Chromosome Partitioning in Escherichia coli in the Absence of Dam-Directed Methylation

1992 • 17 citations

Roles of DNA adenine methylation in controlling replication of the REPI replicon of plasmid pColV‐K30

1991 • 16 citations

Type I and Type III Restriction-Modification Enzymes

1984 • 16 citations

A circular form of bacteriophage P1 DNA made in lytically infected cells of Escherichia coli Characterization and kinetics of formation

1980 • 15 citations

The complete sequence of theBacillus amyloliquefaciensproviral H2,BamHI methylase gene

1990 • 15 citations

Inhibition of DNA synthesis at the hemimethylated pBR322 origin of replication by a cell membrane fraction

1992 • 14 citations

Isolation of temperature-sensitive McrA and McrB mutations and complementation analysis of the McrBC region of Escherichia coli K-12

1991 • 13 citations

Effect of altering GATC sequences in the plasmid ColE1 primer promoter

1990 • 11 citations

Highly efficient positive selection of recombinant plasmids using a novel rglB-based Escherichia coli K-12 vector system

1988 • 9 citations

Close relationship between theHinfI and DpnA DNA-methyltransferase

1989 • 5 citations

[Methyl-cytosine specific restriction in Escherichia coli K-12].

1989 • 5 citations

Mapping by transduction of mutator gene mutH in Escherichia coliz

1978 • 2 citations

Endonuclease from Acholeplasma laidlawii strain JA1 associated with in vivo restriction of DNA containing 5-methylcytosine.

1987 • 2 citations

Deleted Work

1955 • 0 citations