Cloning and characterization of the genes encoding theMspl restriction modification system

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. 1977.

1992 • 4,683 citations

Progressive sequence alignment as a prerequisitetto correct phylogenetic trees

1987 • 1,899 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences

1982 • 801 citations

On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs

1983 • 404 citations

MspI, an isoschizomer of HpaII which cleaves both unmethylated and methylated HpaII sites

1978 • 395 citations

Sequence data handling by computer

1977 • 356 citations

Escherichia coli K-12 restricts DNA containing 5-methylcytosine.

1986 • 325 citations

Specificity of<u>Hpa</u>II and<u>Hae</u>II DNA methylases

1977 • 221 citations

Further procedures for sequence analysis by computer

1978 • 188 citations

Nudeotide sequence of the BsuRI restriction-modification system

1985 • 135 citations

Cloning the modification methylase gene of Bacillus sphaericus R in Escherichia coli

1980 • 116 citations

Nucleotide sequence and expression of the gene encoding theEcoRII modification enzyme

1987 • 106 citations

Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase.

1987 • 90 citations

Cloning of the MspI modification enzyme. The site of modification and its effects on cleavage by MspI and HpaII.

1983 • 90 citations

Computer programs for the assembly of DNA sequences

1979 • 77 citations

Organization of multispecific DNA methyltransferases encoded by temperate Bacillus subtilis phages.

1987 • 74 citations

The GATATC‐modification enzyme EcoRV is closely related to the GATC‐recognizing methyltransferases DpnII and dam from E. coli and phage T₄

1987 • 73 citations

DNA methyltransferase genes of Bacillus subtilis phages: comparison of their nucleotide sequences

1986 • 69 citations

Restriction and modification in Bacillus subtilis: nucleotide sequence, functional organization and product of the DNA methyltransferase gene of bacteriophage SPR

1984 • 67 citations

Structure of the Bacillus sphaericus R modification methylase gene

1983 • 65 citations

Nuclotide sequence of theDdeI restriction-modification system and characterization of the methylase protein

1987 • 56 citations

Structure of the gene coding for the sequence-specific DNA-methyltransferase of theB. subtilisphage SPR

1984 • 53 citations

Cloning and complete nucleotide sequences of the type II restriction-modification genes of Salmonella infantis

1988 • 51 citations

Sequence analysis of theNgoPII methyltransferase gene fromNeisseria gonorrhoeaeP9: homologies with other enzymes recognizing the sequence 5′-GGCC-3′

1988 • 39 citations

Computer programs for handling nucleic acid sequences

1984 • 38 citations

Computer programs for nucleic acid sequence manipulation

1982 • 31 citations

Cloning and expression of the MspI restriction and modification genes

1988 • 29 citations