Organization of restriction-modification systems

Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells

1988 • 891 citations

Predictive motifs derived from cytosine methyltransferases

1989 • 505 citations

Sequence diversity among related genes for recognition of specific targets in DNA molecules

1983 • 478 citations

Complementary specificity of restriction endonucleases of Diplococcus pneumoniae with respect to DNA methylation

1977 • 369 citations

DNA methylation, biochemistry, and biological significance

1984 • 343 citations

Escherichia coli K-12 restricts DNA containing 5-methylcytosine.

1986 • 325 citations

Restriction enzymes and their isoschizomers

1990 • 271 citations

Cytosine-specific type II DNA methyltransferases

1989 • 230 citations

Cloning, characterization, and expression inEscherichia coliof the gene coding for the CpG DNA methylase fromSpiroplasma sp.strain MQ1(M Sssl)

1990 • 214 citations

The great GATC: DNA methylation in E. coli

1989 • 203 citations

Structure and Mechanism of Multifunctional Restriction Endonucleases

1981 • 201 citations

Sequence analysis of the DNA encoding the Eco RI endonuclease and methylase.

1981 • 194 citations

A deoxyribonuclease of Diplococcus pneumoniae specific for methylated DNA

1975 • 192 citations

The Isolation and Characterization of theEsherichia ColiDNA adenine methylase(dam)gene

1983 • 177 citations

Site-specific methylases induce the SOS DNA repair response in Escherichia coli

1987 • 169 citations

DNA sequences of structural genes for Eco RI DNA restriction and modification enzymes.

1981 • 167 citations

Specificity of restriction endonucleases and DNA modification methyltransferases — a review (edition 3)

1990 • 167 citations

Characterization of a unique methyl-specific restriction system in Streptomyces avermitilis

1988 • 163 citations

Sequence motifs characteristic of DNA[cytosine-N4]methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases

1989 • 152 citations

A family of regulatory genes associated with type II restriction-modification systems

1991 • 150 citations

Cloning of a restriction-modification system from Proteus vulgaris and its use in analyzing a methylase-sensitive phenotype in Escherichia coli

1985 • 141 citations

Model for how type I restriction enzymes select cleavage sites in DNA.

1988 • 138 citations

Characterization of the genes coding for theEcoRV restriction and modification system ofEscherichia coli

1984 • 135 citations

Nudeotide sequence of the BsuRI restriction-modification system

1985 • 135 citations

The hsd (host specificity) genes of E. coli K12

1980 • 130 citations

Escherichia coli dam methylase. Physical and catalytic properties of the homogeneous enzyme.

1982 • 129 citations

Specific mismatch correction in bacteriophage lambda crosses by very short patch repair

1983 • 125 citations

Genetic basis of the complementary Dpnl and Dpnll restriction systems of S. pneumoniae: An intercellular cassette mechanism

1986 • 121 citations

Genetic and physical mapping of the mcrA (rglA) and mcrB (rglB) loci of Escherichia coli K-12.

1989 • 117 citations

Cloning the modification methylase gene of Bacillus sphaericus R in Escherichia coli

1980 • 116 citations

Evolution of type II DNA methyltransferases

1989 • 110 citations

Cloning of restriction and modification genes in E. coli: The HhaII system from Haemophilus haemolyticus

1978 • 109 citations

Cloned restriction/modification system from Pseudomonas aeruginosa.

1983 • 108 citations

A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene

1990 • 108 citations

Nucleotide sequence and expression of the gene encoding theEcoRII modification enzyme

1987 • 106 citations

Basis for changes in DNA recognition by the Type I DNA restriction and modification enzymes

1989 • 103 citations

Genetic and sequence organization of the mcrBC locus of Escherichia coli K-12

1990 • 99 citations

Reassortment of DNA recognition domains and the evolution of new specificities

1987 • 97 citations

Construction and use of chimeric SPR/phi 3T DNA methyltransferases in the definition of sequence recognizing enzyme regions.

1987 • 96 citations

Type III DNA restriction and modification systems EcoP1 and EcoP15

1988 • 95 citations

Genetic recombination can generate altered restriction specificity.

1984 • 90 citations

Cloning, sequencing, in vivo promoter mapping, and expression in Escherichia coli of the gene for the HhaI methyltransferase.

1987 • 90 citations

Cloning of the MspI modification enzyme. The site of modification and its effects on cleavage by MspI and HpaII.

1983 • 90 citations

Cloning, sequencing and expression of theTaqI restriction-modification system

1987 • 89 citations

Efficient transformation of Bacillus thuringiensis requires nonmethylated plasmid DNA

1991 • 89 citations

Nucleotide sequence of the FokI restriction-modification system: separate strand-specificity domains in the methyltransferase

1989 • 86 citations

Organization and sequence of the hsd genes of Escherichia coli K-12

1987 • 85 citations

Nucleotide sequence of thePaeR7 restriction/modification system and partial characterization of its protein products

1985 • 84 citations

Cytosine-specific DNA modification interferes with plasmid establishment in Escherichia coli K12: Involvement of rglB

1986 • 82 citations

The nucleotide sequence of the HhaII restriction and modification genes from Haemophilus haemolyticus

1983 • 80 citations

Nucleotide sequence of the Dpn II DNA methylase gene of Streptococcus pneumoniae and its relationship to the dam gene of Escherichia coli.

1985 • 80 citations

The effect of site-specific DNA methylation on restriction endonucleases and DNA modification methyltransferases — a review

1988 • 77 citations

Type II restriction—modification systems

1988 • 77 citations

Cloning type-II restriction and modification genes

1988 • 75 citations

Organization of multispecific DNA methyltransferases encoded by temperate Bacillus subtilis phages.

1987 • 74 citations

Common evolutionary origin of the phage T4 dam and host Escherichia coli dam DNA-adenine methyltransferase genes

1985 • 74 citations

A hybrid recognition sequence in a recombinant restriction enzyme and the evolution of DNA sequence specificity

1985 • 74 citations

Two DNA recognition domains of the specificity polypeptides of a family of type I restriction enzymes.

1986 • 74 citations

The organization and complete nucleotide sequence of the PstI restriction-modification system.

1984 • 74 citations

Chimeric multispecific DNA methyltransferases with novel combinations of target recognition

1988 • 72 citations

Conservation of complex DNA recognition domains between families of restriction enzymes

1989 • 71 citations

Regulation of a new bacteriophage T4 gene, 69, that spans an origin of DNA replication.

1984 • 71 citations

Characterization of the cloned BamHI restriction modification system: its nucleotide sequence, properties of the methylase, and expression in heterologous hosts

1991 • 69 citations

DNA methyltransferase genes of Bacillus subtilis phages: comparison of their nucleotide sequences

1986 • 69 citations

EcoA and EcoE: Alternatives to the EcoK family of type I restriction and modification systems of Escherichia coli

1985 • 67 citations

Restriction and modification in Bacillus subtilis: nucleotide sequence, functional organization and product of the DNA methyltransferase gene of bacteriophage SPR

1984 • 67 citations

Comparison of the nucleotide and amino acid sequences of the RsrI and EcoRI restriction endonucleases

1989 • 67 citations

Cloning and expression of the Pst I restriction-modification system in Escherichia coli.

1981 • 66 citations

The FokI Restriction-Modification System

1989 • 66 citations

Gonococci and Meningococci

1988 • 65 citations

Structure of the Bacillus sphaericus R modification methylase gene

1983 • 65 citations

DpnA, a methylase for single-strand DNA in the Dpn II restriction system, and its biological function.

1989 • 62 citations

Conservation of organization in the specificity polypeptides of two families of type I restriction enzymes

1989 • 61 citations

Molecular cloning of a functional dam+ gene coding for phage T4 DNA adenine methylase

1983 • 59 citations

Cloning, characterization and heterologous expression of theSmaI restriction-modification system

1989 • 58 citations

Nuclotide sequence of theDdeI restriction-modification system and characterization of the methylase protein

1987 • 56 citations

Molecular cloning and characterization of the gene encoding the DNA methyltransferase, M.CviBIII, fromChlorellavirus NC-1A

1987 • 54 citations

Cloning and sequencing the HinfI restriction and modification genes

1988 • 53 citations

Structure of the gene coding for the sequence-specific DNA-methyltransferase of theB. subtilisphage SPR

1984 • 53 citations

Recognition of DNA by Type II Restriction Enzymes

1989 • 52 citations

Agmenellum quadruplicatum M.AquI, a novel modification methylase

1990 • 51 citations

Cloning and complete nucleotide sequences of the type II restriction-modification genes of Salmonella infantis

1988 • 51 citations

Retron for the 67-base multicopy single-stranded DNA from Escherichia coli: a potential transposable element encoding both reverse transcriptase and Dam methylase functions.

1990 • 51 citations

Cloning theBamHI restriction modification system

1989 • 51 citations

Cloned restriction-modification systems — a review

1988 • 50 citations

Molecular cloning and expression in Escherichia coli of two modification methylase genes of Bacillus subtilis

1983 • 49 citations

Cloning and characterization of the genes encoding theMspl restriction modification system

1989 • 49 citations

Cloning theDdeI restriction-modification system using a two-step method

1986 • 48 citations

Distribution and diversity of hsd genes in Escherichia coli and other enteric bacteria

1988 • 48 citations

The FokI Restriction-Modification System

1989 • 47 citations

Purification, cloning and sequence analysis ofRsrIDNA methyltransferase: lack of homology between two enzymes,RsrI andEcoRI, that methylate the same nucleotide in Identical recognition sequences

1989 • 46 citations

Cloning and characterization of the dcm locus of Escherichia coli K-12

1986 • 46 citations

Primary sequence of the EcoRII endonuclease and properties of its fusions with beta-galactosidase.

1990 • 46 citations

Nucleotide sequence of the McrB region of Escherichia coli K-12 and evidence for two independent translational initiation sites at the mcrB locus

1989 • 44 citations

A genetic system for isolation and characterization of TaqI restriction endonuclease mutants

1987 • 42 citations

M · FokI methylates adenine in both strands of its asymmetric recognition sequence

1989 • 42 citations

Molecular cloning of EcoRII endonuclease and methylase genes

1980 • 41 citations

Sequence, internal homology and high-level expression of the gene for a DNA-(cytosineN4)-methyltransferase, M-PvuII

1989 • 41 citations

Sequence analysis of theNgoPII methyltransferase gene fromNeisseria gonorrhoeaeP9: homologies with other enzymes recognizing the sequence 5′-GGCC-3′

1988 • 39 citations

Cloning and nucleotide sequence of the genes coding for theSau961 restriction and modification enzymes

1990 • 39 citations

Cloning and characterization of theHpallmethylase gene

1990 • 38 citations

Cloning and analysis of the HaeIII and HaeII methyltransferase genes

1988 • 38 citations

DNA methyltransferase genes of Bacillus subtilis phages: structural relatedness and gene expression

1985 • 36 citations

Cloning and characterization of theMbollrestriction-modification system

1991 • 36 citations

The amino acid sequence of the CCGG recognizing DNA methyltransferase M.BsuFI: implications for the analysis of sequence recognition by cytosine DNA methyltransferases.

1990 • 35 citations

Nucleotide sequence and genetic organization of the NgoPII restriction-modification system of Neisseria gonorrhoeae

1989 • 33 citations

Cloning and characterization of two tandemly arranged DNA methyltransferase genes of Neisseria lactamica: An adenine-specific M.NlaIII and a cytosine-type methylase

1990 • 33 citations

Restriction endonuclease activity induced by NC-1A virus infection of aChlorella-like green alga

1986 • 32 citations

Cloning of the modification methylase gene of Bacillus centrosporus in Escherichia coli

1982 • 31 citations

Molecular cloning, sequencing, and mapping of the bacteriophage T2 dam gene

1988 • 30 citations

Cloning in Streptococcus pneumoniae of the gene for DpnII DNA methylase

1984 • 30 citations

Cloning and expression of the MspI restriction and modification genes

1988 • 29 citations

Cloning and sequencing the cytosine methyltransferase gene M.CviJI from Chlorella virus IL-3A

1990 • 29 citations

Restriction endonucleases of a new type

1988 • 28 citations

Cloning, nucleotide sequence, and expression of theHincll restriction-modification system

1990 • 28 citations

Cloning and expression of Bacillus subtilis phage DNA methyltransferase genes in Escherichia coli and B. subtilis

1986 • 28 citations

Neucleotide sequence of thedcmlocus ofEsherichia coliK12

1989 • 28 citations

Primary structure of a DNA (N6-adenine)-methyltransferase from Escherichia coli virus T1. DNA sequence, genomic organization, and comparative analysis.

1990 • 23 citations

Molecular cloning and characterization of the gene encoding the adenine methyltransferase M.CviRI fromChlorellavirus XZ-6E

1991 • 22 citations

Characterization of the phage P1 dam gene

1988 • 20 citations

Complete nucleotide sequence of thePvuii restriction enzyme gene fromProteus vulgaris

1990 • 20 citations

Nucleotide sequence of the EcoRII restriction endonuclease gene

1989 • 19 citations

A complex family of class-II restriction endonucleases, DsaI–VI, in Dactylococcopsis salina

1991 • 19 citations

Stepwise cloning and molecular characterization of theHgiDI restriction-modification system fromHerpetosiphon giganteus Hpa2

1991 • 19 citations

The Sa1I (SalGI) restriction-modification system of Streptomyces albus G

1988 • 17 citations

Characterization and cloning of MwoI (GCN7GC), a new type-II restriction-modification system from Methanobacterium wolfei

1989 • 17 citations

The EcoDXX1 restriction and modification system: Cloning the genes and homology to type I restriction and modification systems

1989 • 17 citations

Cloning and Nucleotide Sequences of the Ban Restriction-Modification Genes in Bacillus aneurinolyticus

1990 • 17 citations

Cloning of Pseudomonas plasmid pMG7 and its restriction-modification system in Escherichia coli

1982 • 17 citations

Cloning and nucleotide sequence of the gene encoding the Ecal DNA methyltransferase

1990 • 17 citations

Single amino acid changes that alter the DNA sequence specificity of the DNA-[N⁶-adenine] methyltransferase (Dam) of bacteriophage T4

1989 • 16 citations

DNA restriction and modification systems in Neisseria gonorrhoeae

1989 • 16 citations

M.Smal is an N4-methylcytosine specific DNA-methylase

1990 • 15 citations

The complete sequence of theBacillus amyloliquefaciensproviral H2,BamHI methylase gene

1990 • 15 citations

Cloning the FnuDI, Nael, N coI and XbaI restriction-modification systems

1988 • 14 citations

Overproduction and purification of the M·HhaII methyltransferase from Haemophilus haemolyticus

1988 • 14 citations

Cloning the KpnI restriction-modification system in Escherichia coli

1991 • 14 citations

Cloning and structure of theBepI modification methylase

1989 • 13 citations

Two-step cloning and expression in Escherichia coli of the DNA restriction-modification system StyLTI of Salmonella typhimurium

1991 • 11 citations

Nucleotide sequence of the gene encoding theRsrI methyltransferase

1989 • 10 citations

Cloning, purification and characterization of the M·NdeI methyltransferase from Neisseria denitrificans

1988 • 8 citations

Single amino acid changes which alter the sequence specificity of the T4 and T2 (Dam) DNA-adenine methyltransferases

1988 • 7 citations

Cloning of the HhaI and HinPI restriction-modification systems

1988 • 7 citations

The complete sequence of theBacillus amyloliquefaciensstrain H, cellularBamHI methylase gene

1990 • 7 citations

The characterization and cloning of the EagI restriction-modification system

1988 • 4 citations

Expression of closed restriction and modification genes, hjaIRM from jannaschiana in Escherichia coli

1990 • 4 citations

Endonuclease from Acholeplasma laidlawii strain JA1 associated with in vivo restriction of DNA containing 5-methylcytosine.

1987 • 2 citations

[A new type of cleavage of the recognition site by the site-specific endonuclease Bst 4.4I from Bacillus stearothermophilus 4.4].

1988 • 1 citations