Determinants of binding and internalization of tissue-type plasminogen activator by human vascular smooth muscle and endothelial cells

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes

1992 • 2,655 citations

The pathogenesis of coronary artery disease and the acute coronary syndromes (First of two parts)

1992 • 1,958 citations

Lysosomotropic agents

1974 • 1,887 citations

THE SMOOTH MUSCLE CELL

1971 • 1,571 citations

Plasminogen activator inhibitors

1987 • 957 citations

Plasminogen activator inhibitors

1987 • 764 citations

An endothelial cell growth factor from bovine hypothalamus: identification and partial characterization.

1979 • 727 citations

Antibodies to plasminogen activator inhibit human tumor metastasis

1983 • 651 citations

Monensin interrupts the recycling of low density lipoprotein receptors in human fibroblasts

1981 • 593 citations

Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane.

1981 • 587 citations

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

1991 • 586 citations

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase.

1989 • 579 citations

Endothelial cells produce a latent inhibitor of plasminogen activators that can be activated by denaturants.

1985 • 555 citations

Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes.

1992 • 464 citations

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.

1990 • 451 citations

Distribution of the ?2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues

1992 • 385 citations

Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis

1988 • 354 citations

A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein.

1992 • 341 citations

Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator.

1992 • 318 citations

Smooth muscle cells express urokinase during mitogenesis and tissue-type plasminogen activator during migration in injured rat carotid artery.

1990 • 314 citations

Plasminogen activators in tissue remodeling and invasion: mRNA localization in mouse ovaries and implanting embryos.

1989 • 287 citations

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1982 • 279 citations

Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

1992 • 244 citations

Binding of tissue plasminogen activator to cultured human endothelial cells.

1987 • 223 citations

Binding of plasminogen to extracellular matrix.

1986 • 175 citations

Immunocytochemical localization of urokinase-type plasminogen activator in Lewis lung carcinoma.

1984 • 173 citations

The low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor binds and mediates catabolism of bovine milk lipoprotein lipase.

1992 • 157 citations

Identification and characterization of human endothelial cell membrane binding sites for tissue plasminogen activator and urokinase.

1990 • 150 citations

Kinetic analysis of the interactions between plasminogen activator inhibitor 1 and both urokinase and tissue plasminogen activator

1988 • 148 citations

Distribution of plasminogen activator inhibitor (PAI-1) in tissues.

1991 • 146 citations

Association of a plasminogen activator inhibitor (PAI-1) with the growth substratum and membrane of human endothelial cells.

1987 • 135 citations

The endothelial cell tissue plasminogen activator receptor. Specific interaction with plasminogen.

1991 • 122 citations

Tissue-type plasminogen activator binding to human endothelial cells. Evidence for two distinct binding sites.

1988 • 118 citations

Clearance of Tissue Plasminogen Activator by Mannose and Galactose Receptors in the Liver

1990 • 90 citations

Cross-bridge dynamics in human ventricular myocardium. Regulation of contractility in the failing heart.

1992 • 87 citations

Heparin selectively inhibits the transcription of tissue-type plasminogen activator in primate arterial smooth muscle cells during mitogenesis.

1992 • 82 citations

Lactoferrin specifically inhibits endocytosis of chylomicron remnants but not alpha-macroglobulin.

1992 • 80 citations

Interaction of tissue-type plasminogen activator and plasminogen activator inhibitor 1 on the surface of endothelial cells.

1988 • 78 citations

Binding of tissue plasminogen activator to human umbilical vein endothelial cells

1987 • 77 citations

Pharmacokinetic and distribution analysis of variant forms of tissue- type plasminogen activator with prolonged clearance in rat

1989 • 65 citations

Cultured rat aortic vascular smooth muscle cells digest naturally produced extracellular matrix. Involvement of plasminogen-dependent and plasminogen-independent pathways.

1992 • 60 citations

Characterization and properties of cultured human von Willebrand umbilical vein endothelial cells

1981 • 57 citations

Binding of tissue-type plasminogen activator with human endothelial cell monolayers. Characterization of the high affinity interaction with plasminogen activator inhibitor-1.

1990 • 47 citations

A linear amino acid sequence involved in the interaction of t-PA with its endothelial cell receptor

1989 • 41 citations

Endothelial Cells Degrade Extracellular Matrix Proteins Produced In Vitro

1985 • 34 citations

Tissue-plasminogen activator stimulates endothelial cell migration in wound assays

1990 • 18 citations

Analysis of binding protein for tissue-type plasminogen activator in human endothelial cells

1992 • 18 citations

Complete down‐regulation of low‐density‐lipoprotein‐receptor activity in the human hepatoma cell line Hep G2 by β‐migrating very‐low‐density lipoprotein and non‐lipoprotein cholesterol

1992 • 10 citations