Tissue-type plasminogen activator binding to human endothelial cells. Evidence for two distinct binding sites.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Plasminogen activator inhibitors

1987 • 957 citations

Plasminogen activator inhibitors

1987 • 764 citations

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase.

1985 • 731 citations

An endothelial cell growth factor from bovine hypothalamus: identification and partial characterization.

1979 • 727 citations

Synthesis of fibrinolytic activator and inhibitor by endothelial cells

1977 • 484 citations

Evidence for a rapid inhibitor to tissue plasminogen activator in plasma

1983 • 479 citations

The receptor-binding sequence of urokinase. A biological function for the growth-factor module of proteases.

1987 • 479 citations

Synthesis of fibronectin by cultured human endothelial cells.

1978 • 458 citations

Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.

1985 • 450 citations

Cultured bovine endothelial cells produce both urokinase and tissue-type plasminogen activators.

1982 • 362 citations

Autocrine saturation of pro-urokinase receptors on human A431 cells

1986 • 361 citations

Evidence for the Occurrence of a Fast-Acting Inhibitor for Tissue-Type Plasminogen Activator in Human Plasma

1984 • 345 citations

Binding of plasminogen to cultured human endothelial cells.

1986 • 311 citations

Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells.

1986 • 310 citations

Measurement of plasminogen activator inhibitor 1 in biologic fluids with a murine monoclonal antibody-based enzyme-linked immunosorbent assay

1988 • 262 citations

Presence of complement-fixing anti-endothelial cell antibodies in systemic lupus erythematosus.

1984 • 253 citations

Receptor Binding Studies in Adrenergic Pharmacology

1978 • 240 citations

Plasma levels of a specific inhibitor of tissue-type plasminogen activator (and urokinase) in normal and pathological conditions

1984 • 240 citations

Plasminogen activator release during venous stasis and exercise as determined by a new specific assay

1983 • 238 citations

Binding of tissue plasminogen activator to cultured human endothelial cells.

1987 • 223 citations

An endothelial cell-dependent pathway of coagulation.

1985 • 212 citations

Interaction between fibrinogen and cultured endothelial cells. Induction of migration and specific binding.

1985 • 207 citations

N-Terminal Disulphide Knot of Human Fibrinogen

1968 • 199 citations

Extracellular matrix of cultured bovine aortic endothelial cells contains functionally active type 1 plasminogen activator inhibitor

1987 • 188 citations

Binding of plasminogen to extracellular matrix.

1986 • 175 citations

Plasminogen activator-specific inhibitors produced by human monocytes/macrophages.

1987 • 170 citations

Kinetics of the activation of plasminogen by natural and recombinant tissue-type plasminogen activator.

1984 • 159 citations

Complex formation of platelet thrombospondin with histidine-rich glycoprotein.

1984 • 151 citations

Fc and C3 Receptors Induced by Herpes Simplex Virus on Cultured Human Endothelial Cells

1982 • 148 citations

Quantitation and properties of the active and latent plasminogen activator inhibitors in cultures of human endothelial cells

1986 • 130 citations

Studies on the Fibrinolytic System in Human Plasma: Quantitative Determination of Plasminogen Activators and Proactivators

1979 • 123 citations

Production of a fibrinolytic inhibitor by cultured endothelial cells derived from human umbilical vein

1978 • 111 citations

Comparative properties of two clinical preparations of recombinant human tissue-type plasminogen activator in patients with acute myocardial infarction

1987 • 109 citations

Sustained Fibrinolysis After Administration of t-PA Despite Its Short Half-Life in the Circulation

1987 • 107 citations

Variants of human tissue-type plasminogen activator. Fibrin binding, fibrinolytic, and fibrinogenolytic characterization of genetic variants lacking the fibronectin finger-like and/or the epidermal growth factor domains.

1988 • 89 citations

Receptor Binding Studies in Adrenergic Pharmacology

1979 • 84 citations

Binding of tissue plasminogen activator to human umbilical vein endothelial cells

1987 • 77 citations

Isolation and characterization of a urokinase-type plasminogen activator (Mr = 54,000) from cultured human endothelial cells indistinguishable from urinary urokinase.

1984 • 77 citations

Pharmacokinetics and Effects on Fibrinolytic and Coagulation Parameters of Two Doses of Recombinant Tissue-Type Plasminogen Activator in Healthy Volunteers

1986 • 72 citations

Evidence that cell surface heparan sulfate is involved in the high affinity thrombin binding to cultured porcine aortic endothelial cells.

1985 • 72 citations

Dose-dependent thrombolysis, pharmacokinetics and hemostatic effects of recombinant human tissue-type plasminogen activator for coronary thrombosis

1986 • 71 citations

Cryptic urokinase binding sites on human foreskin fibroblasts

1985 • 71 citations

Physiologic and Pharmacologic Enhancement of Fibrinolysis

1984 • 65 citations

Characterization and properties of cultured human von Willebrand umbilical vein endothelial cells

1981 • 57 citations

Cellular catabolism of recombinant tissue-type plasminogen activator. Identification and characterization of a novel high affinity uptake system on rat hepatocytes.

1987 • 56 citations

Serum-mediated suppression of cell-associated plasminogen activator activity in cultured endothelial cells

1980 • 51 citations

An improved microtiter plate method to measure the potency of plasminogen activators

1984 • 3 citations