The Pathogenesis of Coronary Artery Disease and the Acute Coronary Syndromes

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Compensatory Enlargement of Human Atherosclerotic Coronary Arteries

1987 • 3,549 citations

Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial Infarction

1980 • 2,722 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Book ReviewAmbulatory Pediatric Care

1989 • 2,075 citations

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

1989 • 1,914 citations

Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?

1988 • 1,483 citations

Angiographic progression of coronary artery disease and the development of myocardial infarction

1988 • 1,450 citations

Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque.

1986 • 1,323 citations

INFLUENCE OF PLAQUE CONFIGURATION AND STRESS DISTRIBUTION ON FISSURING OF CORONARY ATHEROSCLEROTIC PLAQUES

1989 • 1,249 citations

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque.

1989 • 1,233 citations

Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors.

1990 • 1,132 citations

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines.

1985 • 1,110 citations

Inhibition of Neointimal Smooth Muscle Accumulation After Angioplasty by an Antibody to PDGF

1991 • 1,081 citations

Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence of recurrent mural thrombosis with peripheral embolization culminating in total vascular occlusion.

1985 • 1,053 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

CLINICAL FEATURES OF SUDDEN OBSTRUCTION OF THE CORONARY ARTERIES

1912 • 893 citations

Coronary Angioscopy in Patients with Unstable Angina Pectoris

1986 • 877 citations

Selective intracoronary thrombolysis in acute myocardial infarction and unstable angina pectoris.

1981 • 811 citations

Angiographie morphology and the pathogenesis of unstable angina pectoris

1985 • 811 citations

Thrombosis as a factor in the pathogenesis of coronary atherosclerosis

1946 • 782 citations

Syndromes of accelerated atherosclerosis: Role of vascular injury and smooth muscle cell proliferation

1990 • 765 citations

Intravascular ultrasound assessment of lumen size and wall morphology in normal subjects and patients with coronary artery disease.

1991 • 673 citations

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis.

1988 • 655 citations

Balloon angioplasty. Natural history of the pathophysiological response to injury in a pig model.

1985 • 633 citations

Regulation of differentiated properties and proliferation of arterial smooth muscle cells.

1990 • 556 citations

Role of basic fibroblast growth factor in vascular lesion formation.

1991 • 521 citations

Insights into the pathogenesis of acute ischemic syndromes.

1988 • 483 citations

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.

1988 • 481 citations

Angiographic evolution of coronary artery morphology in unstable angina

1986 • 464 citations

Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implications.

1989 • 461 citations

Influence of coronary collateral vessels on myocardial infarct size in humans. Results of phase I thrombolysis in myocardial infarction (TIMI) trial. The TIMI Investigators.

1991 • 426 citations

Plaque fissures in human coronary thrombosis

1966 • 424 citations

Coronary Arteriographic Findings Soon after Non-Q-Wave Myocardial Infarction

1986 • 424 citations

Consequences of reocclusion after successful reperfusion therapy in acute myocardial infarction. TAMI Study Group.

1990 • 423 citations

Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery.

1989 • 420 citations

The frequency and significance of coronary arterial thrombi and other observations in fatal acute myocardial infarction

1972 • 419 citations

Significance of the angiographic morphology of localized coronary stenoses: histopathologic correlations.

1982 • 410 citations

Cell biology of arterial proteoglycans.

1989 • 409 citations

Factors influencing the presence or absence of acute coronary artery thrombi in sudden ischaemic death

1989 • 396 citations

Production of Platelet-Derived Growth Factor–like Mitogen by Smooth-Muscle Cells from Human Atheroma

1988 • 333 citations

The pathogenesis of atherosclerosis: An overview

1991 • 306 citations

Morphologic features of unstable atherothrombotic plaques underlying acute coronary syndromes

1989 • 302 citations

The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits. Smooth muscle cell proliferation and re-endothelialization.

1977 • 292 citations

Resistance to Arteriosclerosis in Pigs with von Willebrand's Disease

1978 • 279 citations

The relationship between coronary artery lesions and myocardial infarcts: Ulceration of atherosclerotic plaques precipitating coronary thrombosis

1977 • 275 citations

Identification and distribution of fibrinogen, fibrin, and fibrin(ogen) degradation products in atherosclerosis. Use of monoclonal antibodies.

1989 • 269 citations

Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture

1988 • 263 citations

Progression of coronary atherosclerosis: Is coronary spasm related to progression?

1991 • 254 citations

Incomplete lysis of thrombus in the moderate underlying atherosclerotic lesion during intracoronary infusion of streptokinase for acute myocardial infarction: quantitative angiographic observations.

1986 • 251 citations

Morphology of the endothelium over atherosclerotic plaques in human coronary arteries.

1988 • 243 citations

Delineation of the Extent of Coronary Atherosclerosis by High-Frequency Epicardial Echocardiography

1987 • 219 citations

Binding of thrombin to subendothelial extracellular matrix. Protection and expression of functional properties.

1989 • 212 citations

Fate of fibrinogen in human arterial intima.

1990 • 202 citations

Monocytic origin of foam cells in human atherosclerotic plaques

1984 • 202 citations

Regulation of Smooth Muscle Cell Growth in Injured Artery

1989 • 167 citations

Serial angiographic assessment of coronary artery obstruction and collateral flow in acute myocardial infarction. Report from the second Mount Sinai-New York University Reperfusion Trial.

1989 • 159 citations

Rupture of coronary vasa vasorum as a trigger of acute myocardial infarction

1990 • 145 citations

The dynamics of progression of coronary atherosclerosis studied in 168 medically treated patients who underwent coronary arteriography three times

1989 • 142 citations

Angiographic demonstration of a common link between unstable angina pectoris and non-Q wave acute myocardial infarction

1988 • 138 citations

Clinical and angiographic predictors of new total coronary occlusion in coronary artery disease: Analysis of 313 nonoperated patients

1984 • 136 citations

Morphologic comparison of frequency and types of acute lesions in the major epicardial coronary arteries in unstable angina pectoris, sudden coronary death and acute myocardial infarction

1991 • 135 citations

MACROPHAGES AND ATHEROGENESIS

1987 • 134 citations

Determinants of collateral filling observed during sudden controlled coronary artery occlusion in human subjects

1989 • 125 citations

Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways.

1990 • 115 citations

Monocyte chemotactic factor produced by large vessel endothelial cells in vitro.

1986 • 110 citations

The role of collateral circulation in the various coronary syndromes.

1979 • 100 citations

Flow Patterns in Vessels of Simple and Complex Geometriesa

1987 • 93 citations

Arteriosclerosis in normal and von Willebrand pigs: long-term prospective study and aortic transplantation study.

1982 • 92 citations

Angiographic assessment of the culprit coronary artery lesion before acute myocardial infarction

1990 • 90 citations

Morphologic and dynamic changes of atherosclerotic plaque at the carotid artery bifurcation: Sequential imaging by real time B-mode ultrasonography

1988 • 64 citations

Morphodynamic Interpretation of Acute Coronary Thrombosis, with Special Reference to Volcano-Like Eruption of Atheromatous Plaque Caused by Coronary Artery Spasm

1988 • 63 citations

Irregular coronary lesion morphology after thrombolysis predicts early clinical instability

1991 • 61 citations

Native low density lipoprotein. Endothelial cell recruitment of mononuclear cells.

1991 • 55 citations

Myocardial infarction with minimal coronary atherosclerosis in the era of thrombolytic reperfusion

1991 • 53 citations

Coronary constriction in acute myocardial infarction: role of nitrates

1988 • 51 citations

GISSI-2 and the heparin controversy

1990 • 48 citations

Angiographic assessment of the infarct-related residual coronary stenosis after spontaneous or therapeutic thrombolysis

1990 • 41 citations

Molecular cardiology: New avenues for the diagnosis and treatment of cardiovascular disease

1989 • 31 citations

Effect of balloon inflation on smooth muscle cell proliferation in the porcine carotid artery

1990 • 20 citations

What will be the requirements for acute interventional procedures in Europe?

1987 • 18 citations

Platelets and atherogenesis

1968 • 18 citations