The Drosophila trithorax protein binds to specific chromosomal sites and is co-localized with Polycomb at many sites.

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1992 • 944 citations

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1992 • 850 citations

Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

1994 • 766 citations

BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

1993 • 668 citations

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

1994 • 662 citations

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

1993 • 598 citations

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

1992 • 596 citations

Facilitated binding of TATA-binding protein to nucleosomal DNA

1994 • 593 citations

The protein encoded by the Drosophila position-effect variegation suppressor gene Su(var)3-9 combines domains of antagonistic regulators of homeotic gene complexes.

1994 • 560 citations

Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila.

1988 • 460 citations

Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts

1988 • 454 citations

Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement.

1994 • 410 citations

The Trithorax-like gene encodes the Drosophila GAGA factor

1994 • 409 citations

Sequence-Specific Antirepression of Histone H1-Mediated Inhibition of Basal RNA Polymerase II Transcription

1991 • 378 citations

Mapping polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin

1993 • 360 citations

Genes controlling segmental specification in the Drosophila thorax.

1982 • 360 citations

[33] High-expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors

1991 • 350 citations

A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression.

1994 • 346 citations

Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster.

1992 • 335 citations

Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function.

1993 • 319 citations

Elements of the Drosophila Bithorax Complex That Mediate Repression by Polycomb Group Products

1993 • 317 citations

In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster

1989 • 302 citations

Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products

1992 • 292 citations

Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila.

1985 • 278 citations

(CT)n (GA)n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene.

1993 • 251 citations

Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes

1991 • 242 citations

The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax.

1993 • 235 citations

Nucleosome Core Displacement in Vitro via a Metastable Transcription Factor-Nucleosome Complex

1992 • 198 citations

The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains.

1990 • 196 citations

The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb.

1992 • 193 citations

Regulatory elements of the bithorax complex that control expression along the anterior-posterior axis.

1990 • 162 citations

The Polycomb group gene Posterior Sex Combs encodes a chromosomal protein

1993 • 141 citations

Molecular characterisation of the Polycomblike gene of Drosophila melanogaster, a trans-acting negative regulator of homeotic gene expression

1994 • 139 citations

Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases.

1993 • 139 citations

Organogenesis in Drosophila melanogaster. embryonic salivary gland determination is controlled by homeotic and dorsoventral patterning genes

1992 • 135 citations

Isolation, structure, and expression of labial, a homeotic gene of the Antennapedia Complex involved in Drosophila head development.

1989 • 132 citations

The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related.

1989 • 130 citations

The Drosophila trithorax gene encodes a chromosomal protein and directly regulates the region-specific homeotic gene fork head.

1994 • 125 citations

trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each

1993 • 119 citations

A genetic and developmental analysis of mutations in the Deformed locus in Drosophila melanogaster

1987 • 117 citations

Accurate and efficient RNA polymerase II transcription with a soluble nuclear fraction derived from Drosophila embryos.

1991 • 96 citations

The large upstream control region of the Drosophila homeotic gene Ultrabithorax

1991 • 94 citations

Homoeosis in Drosophila: A description of the polycomb lethal syndrome

1983 • 84 citations

Molecular characterization of the trithorax gene, a positive regulator of homeotic gene expression in Drosophila

1991 • 82 citations

A clonal analysis of the requirement for the trithorax gene in the diversification of segments in Drosophila

1985 • 72 citations

The bithorax complex is regulated by trithorax earlier during Drosophila embryogenesis than is the Antennapedia complex, correlating with a bithorax-like expression pattern of distinct early trithorax transcripts

1994 • 68 citations

(CT)_n (GA)_n Repeats and Heat Shock Elements Have Distinct Roles in Chromatin Structure and Transcriptional Activation of the Drosophila hsp26 Gene

1993 • 62 citations

Dosage-Dependent Modifiers of Homoeotic Mutations in Drosophila melanogaster

1987 • 57 citations

The Drosophila Polycomb-Group Gene Enhancer of zeste Contains a Region with Sequence Similarity to trithorax

1993 • 53 citations

Mutations in somePolycomb group genes ofDrosophila interfere with regulation of segmentation genes

1994 • 40 citations

Blocking cell division does not remove the requirement for Polycomb function in Drosophila embryogenesis

1990 • 24 citations