Molecular characterization of the trithorax gene, a positive regulator of homeotic gene expression in Drosophila

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

The embryonic development of Drosophila melanogaster

1938 • 2,188 citations

Improved technique utilizing nonfat dry milk for analysis of proteins and nucleic acids transferred to nitrocellulose

1984 • 1,697 citations

The Embryonic Development of Drosophila melanogaster

1985 • 1,371 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

Chromosomal walking and jumping to isolate DNA from the Ace and rosy loci and the bithorax complex in Drosophila melanogaster

1983 • 626 citations

Genetic organization of Drosophila bithorax complex

1985 • 514 citations

The actin genes of drosophila: a dispersed multigene family

1980 • 470 citations

Developmental Order: Its Origin and Regulation

1983 • 463 citations

A group of genes controlling the spatial expression of the bithorax complex in Drosophila

1985 • 413 citations

Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein

1985 • 406 citations

Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia

1987 • 391 citations

Protein products of the bithorax complex in Drosophila

1984 • 373 citations

A gene product required for correct initiation of segmental determination in Drosophila

1981 • 361 citations

Molecular and Genetic Organization of The Antennapedia Gene Complex of Drosophila melanogaster

1990 • 360 citations

The molecular organization of the Antennapedia locus of drosophila

1983 • 331 citations

THE BITHORAX COMPLEX

1987 • 326 citations

Analysis of larval segmentation in lethal genotypes associated with the Antennapedia gene complex in Drosophila melanogaster

1981 • 325 citations

In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster

1989 • 302 citations

Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells

1989 • 291 citations

A transposable P vector that confers selectable G418 resistance to Drosophila larvae

1985 • 286 citations

The segmentation and homeotic gene network in early Drosophila development

1987 • 286 citations

Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila.

1985 • 278 citations

Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues

1989 • 273 citations

Localization of antigenic determinants in whole Drosophila embryos

1983 • 266 citations

POLYCOMBLIKE: A GENE THAT APPEARS TO BE REQUIRED FOR THE NORMAL EXPRESSION OF THE BITHORAX AND ANTENNAPEDIA GENE COMPLEXES OF DROSOPHILA MELANOGASTER

1982 • 258 citations

Functional dissection of ultrabithorax proteins in D. melanogaster

1990 • 255 citations

Regulation of the Ultrabithorax gene of drosophila by other bithorax complex genes

1985 • 255 citations

Regulation of Antennapedia transcript distribution by the bithorax complex in Drosophila

1984 • 244 citations

Spatially Regulated Expression of Homeotic Genes in Drosophila

1985 • 242 citations

Autoregulation of a drosophila homeotic selector gene

1988 • 229 citations

The molecular genetics of the bithorax complex of Drosophila: characterization of the products of the Abdominal-B domain.

1989 • 214 citations

Spatial regulation of antennapedia and bithorax gene expression by the Polycomb locus in Drosophila

1986 • 204 citations

The correct activation of Antennapedia and bithorax complex genes requires the fushi tarazu gene

1986 • 201 citations

The molecular genetics of the bithorax complex of Drosophila: cis-regulation in the Abdominal-B domain.

1990 • 197 citations

A gap gene, hunchback, regulates the spatial expression of Ultrabithorax

1986 • 195 citations

A gene that regulates the bithorax complex differentially in larval and adult cells of Drosophila

1984 • 191 citations

The localization and regulation of Antennapedia protein expression in Drosophila embryos

1986 • 186 citations

The Drosophila su(Hw) gene, which controls the phenotypic effect of the gypsy transposable element, encodes a putative DNA-binding protein.

1988 • 184 citations

Domain of Ultrabithorax expression in Drosophila visceral mesoderm from autoregulation and exclusion

1988 • 178 citations

The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products

1990 • 178 citations

A Drosophila rRNA gene located in euchromatin is active in transcription and nucleolus formation.

1988 • 171 citations

Maternal expression of genes that regulate the bithorax complex of Drosophila melanogaster

1986 • 161 citations

Structure and expression of a family of Ultrabithorax mRNAs generated by alternative splicing and polyadenylation in Drosophila.

1989 • 158 citations

Role of theesc+gene product in ensuring the selective expression of segment-specific homeotic genes inDrosophila

1983 • 156 citations

Spatial regulation of the Antennapedia and Ultrabithorax homeotic genes during Drosophila early development.

1989 • 154 citations

Trithorax: A new homoeotic mutation of Drosophila melanogaster causing transformations of abdominal and thoracic imaginal segments

1980 • 152 citations

Gap genes define the limits of antennapedia and bithorax gene expression during early development in Drosophila.

1988 • 151 citations

Are cross-regulatory interactions between homoeotic genes functionally significant?

1990 • 148 citations

Alternative RNA products from the Ultrabithorax domain of the bithorax complex.

1988 • 135 citations

The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related.

1989 • 130 citations

The expression and regulation of Sex combs reduced protein in Drosophila embryos.

1987 • 127 citations

Expression and function of the homoeotic genes Antennapedia and Sex combs reduced in the embryonic midgut of Drosophila

1990 • 125 citations

Different transcripts of the Drosophila Abd-B gene correlate with distinct genetic sub-functions.

1988 • 118 citations

Differential expression of bithorax complex genes in the absence of the extra sex combs and trithorax genes

1983 • 114 citations

Correlative changes in homoeotic and segmentation gene expression in Krüppel mutant embryos of Drosophila

1986 • 111 citations

Isolation of a cDNA Corresponding to a Developmentally Regulated Transcript in Rat Intestine

1988 • 108 citations

The spatial and temporal deployment ofDfdandScrtranscripts throughout development ofDrosophila

1987 • 99 citations

Polyhomeotic: A gene of Drosophila melanogaster required for correct expression of segmental identity

1985 • 99 citations

Cloning of the homeotic Sex combs reduced gene in Drosophila and in situ localization of its transcripts

1985 • 87 citations

Genes involved in the activation of the bithorax complex ofDrosophila

1981 • 84 citations

Control of the initiation of homeotic gene expression by the gap genes giant and tailless in Drosophila

1990 • 80 citations

Autocatalytic ftz activation and metameric instability induced by ectopic ftz expression

1989 • 80 citations

Control of bithorax complex functions by the segmentation gene fushi tarazu of D. melanogaster

1986 • 78 citations

Evidence that the Abdominal-B r element function is conferred by a trans-regulatory homeoprotein.

1988 • 76 citations

A clonal analysis of the requirement for the trithorax gene in the diversification of segments in Drosophila

1985 • 72 citations

POLYTENIZATION OF THE RIBOSOMAL GENES ON THE X AND Y CHROMOSOMES OF DROSOPHILA MELANOGASTER

1982 • 59 citations

Developmentally regulated alternative splicing of transcripts from the Drosophila homeotic gene Antennapedia can produce four different proteins.

1988 • 53 citations

Trithorax: A new homoeotic mutation ofDrosophila melanogaster

1981 • 47 citations

Ultrabithorax mutations in constant and variable regions of the protein coding sequence

1987 • 47 citations

Genetic studies of mutations at two loci of Drosophila melanogaster which cause a wide variety of homeotic transformations

1987 • 44 citations

Establishment of the Deformed expression stripe requires the combinatorial action of coordinate, gap and pair-rule proteins.

1990 • 43 citations

Segmental determination in Drosophila central nervous system

1985 • 42 citations

THE ROLE OF DOSAGE OF THE REGION 7D1–7D5-6 OF THE X CHROMOSOME IN THE PRODUCTION OF HOMEOTIC TRANSFORMATIONS IN DROSOPHILA MELANOGASTER

1980 • 41 citations

Alternative RNA splicing that is spatially regulated: generation of transcripts from the Antennapedia gene of Drosophila melanogaster with different protein-coding regions.

1988 • 31 citations

Genetic interactions between the Polycomb locus and the Antennapedia and Bithorax complexes of Drosophila

1986 • 31 citations

An essential role of even-skipped for homeotic gene expression in the Drosophila visceral mesoderm.

1989 • 27 citations

Homoeosis in Drosophila: The Lethal Syndrome of the Regulator of bithorax (or trithorax) Locus and Its Interaction With Other Homoeotic Loci

1987 • 15 citations