The Drosophila trithorax gene encodes a chromosomal protein and directly regulates the region-specific homeotic gene fork head.

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

DNA cloning : a practical approach

1985 • 2,302 citations

The Embryonic Development of Drosophila melanogaster

1985 • 1,371 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

brahma: A regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2SWI2

1992 • 951 citations

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1992 • 944 citations

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1992 • 850 citations

The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo

1989 • 760 citations

The Polycomb protein shares a homologous domain with a heterochromatin-associated protein of Drosophila.

1991 • 566 citations

A molecular gradient in early Drosophila embryos and its role in specifying the body pattern

1986 • 504 citations

Dosage-dependent modifiers of polycomb and antennapedia mutations in Drosophila.

1988 • 460 citations

Malignant Neoplasms of Genetic Origin in Drosophila melanogaster

1978 • 441 citations

A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.

1994 • 396 citations

Imprinting a determined state into the chromatin of Drosophila

1990 • 391 citations

The bromodomain: a conserved sequence found in human,Drosophilaand yeast proteins

1992 • 375 citations

Mapping polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin

1993 • 360 citations

Molecular and Genetic Organization of The Antennapedia Gene Complex of Drosophila melanogaster

1990 • 360 citations

Polycomb and polyhomeotic are constituents of a multimeric protein complex in chromatin of Drosophila melanogaster.

1992 • 335 citations

Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on Enhancer of zeste function.

1993 • 319 citations

ISOLATION AND CHARACTERIZATION OF SEX-LINKED FEMALE-STERILE MUTANTS IN DROSOPHILA MELANOGASTER

1975 • 312 citations

In vivo binding pattern of a trans-regulator of homoeotic genes in Drosophila melanogaster

1989 • 302 citations

The segmentation and homeotic gene network in early Drosophila development

1987 • 286 citations

Functional interdependence of the yeast SNF2, SNF5, and SNF6 proteins in transcriptional activation.

1991 • 244 citations

The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax.

1993 • 235 citations

Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster.

1992 • 231 citations

A Drosophila Minute gene encodes a ribosomal protein

1985 • 211 citations

Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster.

1990 • 209 citations

Developmental order, its origin and regulation

1982 • 208 citations

The trithorax gene, a trans-acting regulator of the bithorax complex in Drosophila, encodes a protein with zinc-binding domains.

1990 • 196 citations

The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb.

1992 • 193 citations

Trithorax: A new homoeotic mutation of Drosophila melanogaster causing transformations of abdominal and thoracic imaginal segments

1980 • 152 citations

Transcriptional activation of Drosphila homeotic genes form distant regulatory elements

1993 • 147 citations

Direct interaction of the Polycomb protein with Antennapedia regulatory sequences in polytene chromosomes of Drosophila melanogaster.

1991 • 142 citations

The Polycomb group gene Posterior Sex Combs encodes a chromosomal protein

1993 • 141 citations

Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases.

1993 • 139 citations

Organogenesis in Drosophila melanogaster. embryonic salivary gland determination is controlled by homeotic and dorsoventral patterning genes

1992 • 135 citations

The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related.

1989 • 130 citations

The expression pattern of a Drosophila homolog to the mouse transcription factor HNF-4 suggests a determinative role in gut formation.

1993 • 128 citations

trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each

1993 • 119 citations

Genetic and molecular analysis of fs(1)h, a maternal effect homeotic gene in Drosophila

1986 • 117 citations

Differential expression of bithorax complex genes in the absence of the extra sex combs and trithorax genes

1983 • 114 citations

Mechanisms of heritable gene repression during development of Drosophila

1993 • 113 citations

The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development.

1991 • 111 citations

Mutations in polycombeotic, a Drosophila polycomb-group gene, cause a wide range of maternal and zygotic phenotypes.

1990 • 110 citations

Terminal versus segmental development in the Drosophila embryo: the role of the homeotic gene fork head

1988 • 93 citations

Genes involved in the activation of the bithorax complex ofDrosophila

1981 • 84 citations

Molecular characterization of the trithorax gene, a positive regulator of homeotic gene expression in Drosophila

1991 • 82 citations

The reprogramming of transcriptional competence

1992 • 79 citations

The bithorax complex is regulated by trithorax earlier during Drosophila embryogenesis than is the Antennapedia complex, correlating with a bithorax-like expression pattern of distinct early trithorax transcripts

1994 • 68 citations

The Polycomb gene is differentially regulated during oogenesis and embryogenesis of Drosophila melanogaster

1993 • 57 citations

Trithorax: A new homoeotic mutation ofDrosophila melanogaster

1981 • 47 citations

Regulatory elements controlling expression of the Drosophila homeotic gene fork head.

1990 • 45 citations

Interactions of Polycomb and trithorax with cis regulatory regions of Ultrabithorax during the development of Drosophila melanogaster.

1990 • 40 citations

GENETIC ANALYSIS OF TWO ALLELIC TEMPERATURE-SENSITIVE MUTANTS OF DROSOPHILA MELANOGASTER BOTH OF WHICH ARE ZYGOTIC AND MATERNAL-EFFECT LETHALS

1978 • 40 citations

Cloning and molecular characterization of the trithorax locus of Drosophila melanogaster.

1989 • 38 citations

Information transfer during embryonic induction in amphibians

1985 • 18 citations

Homoeosis in Drosophila: The Lethal Syndrome of the Regulator of bithorax (or trithorax) Locus and Its Interaction With Other Homoeotic Loci

1987 • 15 citations

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