Sequence-Specific Antirepression of Histone H1-Mediated Inhibition of Basal RNA Polymerase II Transcription

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.

1979 • 1,532 citations

Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1

1986 • 1,473 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

EUKARYOTIC TRANSCRIPTIONAL REGULATORY PROTEINS

1989 • 1,299 citations

Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes

1980 • 1,256 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

NUCLEASE HYPERSENSITIVE SITES IN CHROMATIN

1988 • 1,233 citations

The structure of histone H1 and its location in chromatin

1980 • 696 citations

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

1987 • 609 citations

Chromatin

1989 • 606 citations

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter.

1987 • 597 citations

Assembly and propagation of repressed and derepressed chromosomal states

1985 • 518 citations

Alternative chromatin structure at CpG islands

1990 • 480 citations

Removal of positioned nucleosomes from the yeast PHO5 promoter upon PHO5 induction releases additional upstream activating DNA elements.

1986 • 470 citations

Nucleosome loss activates yeast downstream promoters in vivo

1988 • 456 citations

Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts

1988 • 454 citations

Bidirectional SV40 Transcription Mediated by Tandem Sp1 Binding Interactions

1985 • 413 citations

Binding of transcription factor TFIID to the major late promoter during in vitro nucleosome assembly potentiates subsequent initiation by RNA polymerase II

1987 • 394 citations

The higher-order structure of chromatin: evidence for a helical ribbon arrangement.

1984 • 364 citations

The presence of nucleosomes on a DNA template prevents initiation by RNA polymerase II in vitro

1986 • 339 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

In vitro transcription of the Drosophila engrailed gene.

1988 • 284 citations

Changes in histone gene dosage alter transcription in yeast.

1988 • 275 citations

GAL4 derivatives function alone and synergistically with mammalian activators in vitro

1988 • 274 citations

Histone-h1-dependent chromatin superstructures and the suppression of gene activity

1984 • 251 citations

Change in the pattern of histone binding to DNA upon transcriptional activation

1989 • 246 citations

Higher order structure of chromatin: Orientation of nucleosomes within the 30 nm chromatin solenoid is independent of species and spacer length

1983 • 236 citations

Functional steps in transcription initiation and reinitiation from the major late promoter in a HeLa nuclear extract.

1987 • 228 citations

Depletion of histone H4 and nucleosomes activates the PHO5 gene in Saccharomyces cerevisiae.

1988 • 226 citations

Promoter specificity and modulation of RNA polymerase II transcription

1989 • 221 citations

Protein/DNA architecture of the DNase I hypersensitive region of the Drosophila hsp26 promoter.

1988 • 212 citations

Histories H1 and H5: one or two molecules per nucleosome?

1981 • 211 citations

Dominant and specific repression of Xenopus oocyte 5S RNA genes and satellite I DNA by histone H1.

1989 • 188 citations

Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro.

1989 • 187 citations

Chromatin structure of transcriptionally competent and repressed genes.

1990 • 178 citations

Core Particle, Fiber, and Transcriptionally Active Chromatin Structure

1986 • 159 citations

Exchange of histone H1 between segments of chromatin

1981 • 155 citations

A Potent GAL4 Derivative Activates Transcription at a Distance in Vitro

1990 • 148 citations

Salt-dependent co-operative interaction of histone H1 with linear DNA

1986 • 142 citations

Assembly and disassembly of the Drosophila RNA polymerase II complex during transcription.

1990 • 134 citations

Nucleosomes are phased along the mouse β-major globin gene in erythroid and nonerythroid cells

1986 • 119 citations

Histone H1 and the regulation of transcription of eukaryotic genes

1990 • 117 citations

Footprinting of linker histones H5 and H1 on the nucleosome.

1988 • 116 citations

Sequence-specific transcriptional antirepression of the Drosophila Krüppel gene by the GAGA factor.

1991 • 107 citations

Presence of histone H1 on an active Balbiani ring gene

1990 • 101 citations

Chromatin structure and gene activity

1990 • 100 citations

Accurate and efficient RNA polymerase II transcription with a soluble nuclear fraction derived from Drosophila embryos.

1991 • 96 citations

Exchange of Histones H1 and H5 between Chromatin Fragments

1983 • 93 citations

Histone H1 represses transcription from minichromosomes assembled in vitro.

1989 • 92 citations

Transcription of adenovirus 2 major late and peptide IX genes under conditions of in vitro nucleosome assembly.

1987 • 83 citations

A defined structure of the 30 nm chromatin fibre which accommodates different nucleosomal repeat lengths.

1984 • 80 citations

Cross‐linking of Histone H1 in Chromatin

1980 • 78 citations

Upstream Activation Sequence-Dependent Alteration of Chromatin Structure and Transcription Activation of the Yeast GAL1-GAL10 Genes

1989 • 76 citations

Chromatin folding modulates nucleosome positioning in yeast minichromosomes

1988 • 75 citations

Analysis of chromatin structure and DNA sequence organization: use of the 1,10-phenanthroline-cuprous complex

1982 • 72 citations

Differences in the binding of H1 variants to DNA

1988 • 69 citations

The binding of histones H1 and H5 to chromatin in chicken erythrocyte nuclei

1980 • 58 citations

In vitrotranscription with extracts of nuclei ofDrosophilaembryos

1985 • 50 citations

The arrangement of H5 molecules in extended and condensed chicken erythrocyte chromatin.

1985 • 48 citations

Formation and characterization of soluble complexes of histone H1 with supercoiled DNA

1986 • 31 citations

Developmental switch in chromatin structure associated with alternate promoter usage in the Drosophila melanogaster alcohol dehydrogenase gene.

1987 • 25 citations

Nucleotide sequence of aDrosophila melanogasterH1 histone gene

1986 • 22 citations