20-EPI-Vitamin D3 Analogs

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

Social controls on cell survival and cell death

1992 • 2,641 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Apoptosis in cancer therapy: Crossing the threshold

1994 • 1,351 citations

bcl-2-Immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

1989 • 1,252 citations

Theory and Practice of Histotechnology

1973 • 1,145 citations

Theory and Practice of Histotechnology

1981 • 1,106 citations

The Role of the Vitamin D Endocrine System in Health and Disease

1989 • 1,041 citations

Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3.

1981 • 1,025 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes.

1987 • 923 citations

p53-Dependent apoptosis suppresses tumor growth and progression in vivo

1994 • 883 citations

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

1992 • 871 citations

Checkpoints of dueling dimers foil death wishes

1994 • 806 citations

P53 expression in breast cancer

1988 • 612 citations

Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines.

1990 • 607 citations

Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide.

1979 • 602 citations

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion.

1992 • 587 citations

Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

1983 • 585 citations

Geographic variation in breast cancer mortality in the United States: A hypothesis involving exposure to solar radiation

1990 • 579 citations

Progress in Clinical and Biological Research

1989 • 568 citations

Isolation of human‐p53‐specific monoclonal antibodies and their use in the studies of human p53 expression

1986 • 508 citations

1,25-Dihydroxyvitamin D3-induced differentiation in a human promyelocytic leukemia cell line (HL-60): receptor-mediated maturation to macrophage-like cells.

1984 • 461 citations

1α,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells

1981 • 460 citations

1,25(OH) ₂ ‐Vitamin D ₃ receptors: gene regulation and genetic circuitry

1988 • 455 citations

Vitamin D. Chemical, Biochemical and Clinical Update

1985 • 325 citations

1 alpha,25-Dihydroxyvitamin D3 inhibits gamma-interferon synthesis by normal human peripheral blood lymphocytes.

1987 • 323 citations

20-EPI-vitamin D3 analogues: A novel class of potent regulators of cell growth and immune responses

1991 • 320 citations

Suppression of in vivo growth of human cancer solid tumor xenografts by 1,25-dihydroxyvitamin D3.

1987 • 312 citations

POSSIBLE ROLE FOR VITAMIN D IN CONTROLLING BREAST CANCER CELL PROLIFERATION

1989 • 284 citations

1,25-Dihydroxyvitamin D3: in vivo and in vitro effects on human preleukemic and leukemic cells.

1985 • 275 citations

Inhibition of human cancer cell growth by 1,25-dihydroxyvitamin D3 metabolites.

1983 • 264 citations

1 alpha,25-Dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells.

1983 • 257 citations

Effects of synthetic vitamin d analogues on breast cancer cell proliferation in vivo and in vitro

1992 • 237 citations

Induction of macrophage differentiation of human normal and leukemic myeloid stem cells by 1,25-dihydroxyvitamin D3 and its fluorinated analogues.

1984 • 236 citations

Modern Trends in Human Leukemia

1983 • 235 citations

γ-interferon stimulates production of 1,25-dihydroxyvitamin D3 by normal human macrophages

1985 • 232 citations

Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells.

1982 • 224 citations

Sunlight and Breast Cancer Incidence in the USSR

1990 • 209 citations

DEMONSTRATION OF 1,25-DIHYDROXYVITAMIN D₃RECEPTORS IN HUMAN SKIN BIOPSIES

1980 • 194 citations

Vitamin D compounds. Effect on clonal proliferation and differentiation of human myeloid cells.

1986 • 193 citations

20-epi-vitamin D3 analogues: a novel class of potent inhibitors of proliferation and inducers of differentiation of human breast cancer cell lines.

1995 • 188 citations

Regulation of 1,25-Dihydroxyvitamin D₃Production by Cultured Alveolar Macrophages from Normal Human Donors and from Patients with Pulmonary Sarcoidosis*

1987 • 187 citations

UCLA symposia on molecular and cellular biology

1982 • 173 citations

1,25-Dihydroxy-16-ene-23-yne-vitamin D3 prolongs survival time of leukemic mice.

1990 • 167 citations

Molecular Biology of the Vitamin D Hormone

1988 • 167 citations

1,25-DIHYDROXYVITAMIN-D RECEPTOR IN BREAST CANCER CELLS

1979 • 158 citations

Synthesis in vitro of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 by interferon-gamma-stimulated normal human bone marrow and alveolar macrophages.

1987 • 152 citations

Calcipotriol (MC 903), a novel vitamin D3 analogue stimulates terminal differentiation and inhibits proliferation of cultured human keratinocytes

1990 • 146 citations

Influence of 1,25-dihydroxyvitamin D3 on cultured osteogenic sarcoma cells: correlation with the 1,25-dihydroxyvitamin D3 receptor.

1984 • 144 citations

Novel vitamin D analogs that modulate leukemic cell growth and differentiation with little effect on either intestinal calcium absorption or bone mobilization

1989 • 133 citations

25-Hydroxyvitamin D₃Metabolism by Lipopolysaccharide-Stimulated Normal Human Macrophages*

1987 • 124 citations

Topical calcipotriol treatment in advanced breast cancer

1991 • 123 citations

Development and characterization of nontumorigenic and tumorigenic epithelial cell lines from rat dorsal-lateral prostate.

1994 • 116 citations

Differentiation of cultured human breast cancer cells (AU‐565 and MCF‐7) associated with loss of cell surface HER‐2/neu antigen

1990 • 115 citations

Differentiation of a human monocytic cell line by 1,25-dihydroxyvitamin D3 (calcitriol): a morphologic, phenotypic, and functional analysis

1984 • 114 citations

Granulocyte-macrophage colony-stimulating factor. Sensitive and receptor-mediated regulation by 1,25-dihydroxyvitamin D3 in normal human peripheral blood lymphocytes.

1987 • 114 citations

EB 1089, a novel vitamin D analogue, has strong antiproliferative and differentiation inducing effects on cancer cells

1993 • 106 citations

The cellular protein p53 in human tumours.

1984 • 104 citations

[Hematology and blood transfusion].

1982 • 102 citations

Structure-function studies on analogues of 1 alpha,25-dihydroxyvitamin D3: differential effects on leukemic cell growth, differentiation, and intestinal calcium absorption.

1990 • 99 citations

Apoptosis II The molecular basis of apoptosis in disease

1995 • 92 citations

Development of a novel 1,25(OH)2-vitamin D3 analog with potent ability to induce HL-60 cell differentiation without modulating calcium metabolism

1991 • 92 citations

The bcl-2 oncogene and apoptosis.

1992 • 90 citations

1,25-dihydroxyvitamin D3 receptors in human epithelial cancer cell lines.

1982 • 89 citations

24- and 26-homo-1,25-dihydroxyvitamin D3: preferential activity in inducing differentiation of human leukemia cells HL-60 in vitro.

1987 • 87 citations

NORMAL AND MALIGNANT BREAST TISSUE IS A TARGET ORGAN FOR 1, 25‐(OH)₂ VITAMIN D₃

1980 • 74 citations

Nutrient Modulation of the Immune Response

2020 • 73 citations

Vitamin D3 analogs: Effect on leukemic clonal growth and differentiation, and on serum calcium levels

1995 • 72 citations

1,25-Dihydroxyvitamin D3 receptor RNA: expression in hematopoietic cells

1991 • 71 citations

Human colon cell line HT-29: Characterisation of 1,25-dihydroxyvitamin D3 receptor and induction of differentiation by the hormone

1988 • 64 citations

Studies of vitamin D (calciferol) and its analogs. 39. Arocalciferols: synthesis and biological evaluation of aromatic side-chain analogs of 1.alpha.,25-dihydroxyvitamin D3

1991 • 64 citations

Effect of recombinant monokines, lymphokines, and other agents on clonal proliferation of human lung cancer cell lines.

1987 • 63 citations

Immunocytochemical detection of 1,25-dihydroxyvitamin D3 receptor in breast cancer.

1987 • 62 citations

1,25(OH)2-16ENE-vitamin D3 is a potent antileukemic agent with low potential to cause hypercalcemia

1994 • 61 citations

1 alpha,25-Dihydroxy-20-epi-vitamin D3: an extraordinarily potent inhibitor of leukemic cell growth in vitro

1994 • 60 citations

Vitamin D, chemical, biochemical and clinical update

1987 • 59 citations

1,25-Dihydroxyvitamin D3 modulates the expression of a lymphokine (granulocyte-macrophage colony-stimulating factor) posttranscriptionally.

1988 • 58 citations

Leukemia: Recent Advances in Biology and Treatment.

1986 • 55 citations

Effect of C2O stereochemistry on the conformational profile of the side chains of vitamin D analogs.

1993 • 52 citations

Myeloid cell lines: Tools for studying differentiation of normal and abnormal hematopoietic cells

1988 • 48 citations

In vitro study of effects of 1,25 dihydroxyvitamin D3 on the morphology of human breast cancer cell line BT.20

1989 • 45 citations

Applied Immunohistochemistry

1991 • 44 citations

The effect of vitamin D₃metabolites on normal and leukemic bone marrow cells in vitro

1984 • 35 citations

25-Hydroxyvitamin D3 Metabolism by Human T-Lymphotropic Virus-Transformed Lymphocytes*

1987 • 33 citations

Mutant p53 proteins have diverse intracellular abilities to oligomerize and activate transcription.

1993 • 32 citations

Vitamins and cancer prevention

1987 • 31 citations

Differentiation-inducing agents in the treatment of myelodysplastic syndromes.

1992 • 29 citations

Lymphocyte cell lines from vitamin D-dependent rickets type II show functional defects in the 1α,25-dihydroxyvitamin D3 receptor

1990 • 28 citations

Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A

1992 • 26 citations

Regulation of 25-hydroxyvitamin D3 metabolism in a human promyelocytic leukemia cell line (HL-60): 1,25-Dihydroxyvitamin D3 stimulates the synthesis of 24,25-dihydroxyvitamin D3

1986 • 25 citations

Evidence for 1,25-dihydroxyvitamin D3 production by cultured porcine alveolar macrophages

1991 • 24 citations

Study of differentiation of fresh myelogenous leukemic cells by compounds that induce a human promyelocytic leukemic line (HL-60) to differentiate

1985 • 24 citations

Leukemia: Recent Advances in Biology and Treatment

1987 • 24 citations

Effect of 1 α-hydroxyvitamin D3 on metastasis of rat ascites hepatoma K-231

1984 • 20 citations

Effect of 1,25-dihydroxyvitamin D3 and its analogs on human immunodeficiency virus infection in monocytes/macrophages.

1993 • 19 citations

INHIBITION OF THE CLONAL GROWTH OF HUMAN MYELOID LEUKEMIA CELLS

1982 • 19 citations

Potent vitamin D3 analogs: Their abilities to enhance transactivation and to bind to the vitamin D3 response element

1995 • 18 citations

Is immunoreactivity for p53 useful in distinguishing benign from malignant effusions? Localization of p53 gene product in benign mesothelial and adenocarcinoma cells.

1994 • 15 citations

Production of 1 alpha,25-dihydroxyvitamin D3 by hematopoietic cells.

1990 • 14 citations

Tumor Cell Differentiation: Biology and Pharmacology

1987 • 13 citations

bcl-2 Oncogene Protein Is Preferentially Expressed in Reed-Sternberg Cells in Hodgkin’s Disease of the Nodular Sclerosis Subtype

1994 • 12 citations

Differentiation Therapy of Leukemia

1994 • 11 citations

Molecular and cellular regulation of calcium and phosphate metabolismProgress in Clinical and Biological Research, Volume 332, edited by

1992 • 10 citations

Study of Differentiation and Proliferation of Leukemic Cells Using Myeloid Leukemia Cell Lines

1985 • 9 citations

The biology of human leukemia

1990 • 7 citations

Differentiation of Human Acute Myelogenous Leukemia Cells: Therapeutic Possibilities

1987 • 6 citations

STRUCTURE-FUNCTION RELATIONSHIPS IN THE VITAMIN D ENDOCRINE SYSTEM FOR l,25(OH)2D3 ANALOGS

1991 • 4 citations

1,25(OH)2VITAMIN D3 ANALOGS: COMPARISON OF 1,25(OH)2D3 RECEPTOR LIGAND SPECIFICITY AND BIOLOGICAL ACTIVITY IN THE CHICK AND HUMAN PROMYELOCYTE (HL-60) CELLS.

1988 • 3 citations

INTERACTION BETWEEN THE HEMATOPOIETIC SYSTEM AND THE VITAMIN D ENDOCRINE SYSTEM

1988 • 2 citations

Immunoregulatory and Prodifferentiating Effects of 1,25-Dihydroxyvitamin D3 in Human Mononuclear Cells

2020 • 1 citations

Interaction of 1,25 Dihydroxyvitamin D3 with Normal and Abnormal Hematopoiesis

1987 • 1 citations