Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1988 • 1,699 citations

Okadaic acid: a new probe for the study of cellular regulation

1990 • 1,396 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

c-fos expression is neither sufficient nor obligatory for differentiation of monomyelocytes to macrophages

1986 • 204 citations

and effects of protein phosphatase inhibitors, microcystins and nodularin, on mouse skin and fibroblasts

1990 • 197 citations

Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes

1989 • 179 citations

Transcriptional and post-transcriptional regulation of c-jun expression during monocytic differentiation of human myeloid leukemic cells.

1990 • 169 citations

Structure-activity relationship within a series of okadaic acid derivatives

1990 • 139 citations

Complexities of the Protein Kinase C Pathway

1991 • 131 citations

Differentiation of cultured human breast cancer cells (AU‐565 and MCF‐7) associated with loss of cell surface HER‐2/neu antigen

1990 • 115 citations

Inhibition of protein phosphatases by okadaic acid induces AP1 in human T cells

1991 • 94 citations

Regulation of IMP dehydrogenase gene expression by its end products, guanine nucleotides.

1991 • 73 citations

Induction of differentiation of human promyelocytic leukemia (HL-60) cells by teleocidin and phorbol-12-myristate-13-acetate

1982 • 50 citations

Expression of the jun-B gene during induction of monocytic differentiation.

1991 • 46 citations

Specific protein phosphorylation in human promyelocytic HL-60 leukemia cells susceptible or resistant to induction of cell differentiation by phorbol-12-myristate-13-acetate.

1985 • 44 citations

Induction of differentiation and c‐jun expression in human leukemic cells by okadaic acid, an inhibitor of protein phosphatases

1992 • 28 citations

Protein kinase C activities with different characteristics, including substrate specificity, from two human HL-60 leukemia cell variants.

1988 • 23 citations