Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Gene regulation by proteins acting nearby and at a distance

1986 • 886 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Transcriptional regulation of hemoglobin switching in chicken embryos.

1981 • 800 citations

A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes

1986 • 740 citations

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses.

1988 • 736 citations

The molecular biology of tumor viruses

1974 • 734 citations

Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements

1984 • 669 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

DNA Tumor Viruses

1982 • 550 citations

Multiple sequence motifs are involved in SV40 enhancer function.

1986 • 511 citations

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

1984 • 458 citations

The human oestrogen receptor functions in yeast

1988 • 402 citations

Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitro

1987 • 386 citations

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1985 • 366 citations

The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator

1988 • 362 citations

Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter

1986 • 336 citations

Repressor structure and the mechanism of positive control

1983 • 324 citations

The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence

1988 • 301 citations

Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences

1986 • 298 citations

The SV40 enhancer is composed of multiple functional elements that can compensate for one another

1986 • 293 citations

The SV40 enhancer contains two distinct levels of organization

1988 • 286 citations

The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element.

1987 • 268 citations

The SV40 enhancer can be dissected into multiple segments, each with a different cell type specificity.

1987 • 265 citations

Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer.

1987 • 255 citations

An enhancer-like sequence within the Xenopus U2 gene promoter facilitates the formation of stable transcription complexes

1985 • 250 citations

Discrete elements within the SV40 enhancer region display different cell-specific enhancer activities.

1987 • 240 citations

Repression of the Immunoglobulin Heavy Chain Enhancer by the Adenovirus-2 E1A Products

1985 • 223 citations

Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts

1986 • 209 citations

Two regulatory elements for immunoglobulin kappa light chain gene expression.

1984 • 197 citations

UASs and enhancers: Common mechanism of transcriptional activation in yeast and mammals

1988 • 187 citations

Multiple sequence elements are required for maximal in vitro transcription of a human histone H2B gene.

1986 • 157 citations

In vitro binding of cell-specific and ubiquitous nuclear proteins to the octamer motif of the SV40 enhancer and related motifs present in other promoters and enhancers.

1987 • 149 citations

Specific protein binding to the simian virus 40 enhancer in vitro.

1986 • 135 citations

Promoter Elements of Genes Coding for Proteins and Modulation of Transcription by Estrogens and Progesterone

1984 • 133 citations

In vitro binding of several cell-specific and ubiquitous nuclear proteins to the GT-I motif of the SV40 enhancer.

1987 • 127 citations

One cell-specific and three ubiquitous nuclear proteins bind in vitro to overlapping motifs in the domain B1 of the SV40 enhancer.

1987 • 127 citations

A purine-rich DNA sequence motif present in SV40 and lymphotropic papovavirus binds a lymphoid-specific factor and contributes to enhancer activity in lymphoid cells.

1987 • 110 citations

A mutated polyoma virus enhancer which is active in undifferentiated embryonal carcinoma cells is not repressed by adenovirus-2 E1A products

1986 • 104 citations

Cell-specific activity of the constituent elements of the simian virus 40 enhancer.

1987 • 86 citations

Specific Protein Binding to the Simian Virus 40 Enhancer in Vitro

1986 • 68 citations

Mutational analysis of the contribution of sequence motifs within the IgH enhancer to tissue specific transcriptional activation

1988 • 49 citations

A factor discriminating between the wildtype and a mutant polyomavirus enhancer

1987 • 43 citations

Viral Enhancer Activity in Teratocarcinoma Cells

1985 • 34 citations