Signal transduction by the platelet Fc receptor

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets

1983 • 589 citations

Biochemical mechanisms of platelet activation

1989 • 370 citations

Human monocytes and U937 cells bear two distinct Fc receptors for IgG.

1986 • 337 citations

Highly Cooperative Opening of Calcium Channels by Inositol 1,4,5-Trisphosphate

1988 • 307 citations

Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes.

1989 • 300 citations

Inositol 1,4,5-trisphosphate releases Ca2+ from a Ca2+-transporting membrane vesicle fraction derived from human platelets.

1985 • 268 citations

Regulation of the phosphoinositide hydrolysis pathway in thrombin-stimulated platelets by a pertussis toxin-sensitive guanine nucleotide-binding protein. Evaluation of its contribution to platelet activation and comparisons with the adenylate cyclase inhibitory protein, Gi.

1986 • 235 citations

Human platelet Fc receptor for immunoglobulin G. Identification as a 40,000-molecular-weight membrane protein shared by monocytes.

1985 • 233 citations

The calcium signal and phosphatidylinositol breakdown in 2H3 cells.

1984 • 214 citations

Evidence that Na+/H+ exchange regulates receptor-mediated phospholipase A2 activation in human platelets.

1986 • 196 citations

What turns platelets on?

1984 • 180 citations

Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

1989 • 159 citations

Characterization of the IgG-Fc receptor on human platelets

1982 • 151 citations

Isolation and expression of cDNA clones encoding a human receptor for IgG (Fc gamma RII).

1987 • 150 citations

Thrombin and ionomycin can raise platelet cytosolic Ca2+ to micromolar levels by discharge of internal Ca2+ stores: Studies using fura-2

1986 • 149 citations

Isolation of cDNAs for two distinct human Fc receptors by ligand affinity cloning.

1988 • 148 citations

A role for Gi in control of thrombin receptor-phospholipase C coupling in human platelets.

1988 • 138 citations

Molecular cloning of a human immunoglobulin G Fc receptor.

1988 • 130 citations

Inositol 1,4,5-trisphosphate-induced release of sequestered Ca2+ from highly purified human platelet intracellular membranes

1985 • 114 citations

Purification and Properties of myo-Inositol-1-Phosphatase from Rat Brain

1985 • 86 citations

Inositol triphosphate-induced Ca2+ release from human platelet membranes

1985 • 71 citations

Human Fc gamma receptors: stable inter-donor variation in quantitative expression on platelets correlates with functional responses.

1987 • 62 citations

Na+/H+ exchange as a modulator of platelet activation

1988 • 55 citations

Quantitative analysis of platelet membrane glycoproteins: Effect of platelet washing procedures and isolation of platelet density subpopulations

1981 • 44 citations

Platelet IgG Fc receptor

1987 • 43 citations

GTP and cytosol stimulate phosphoinositide hydrolysis in isolated platelet membranes

1986 • 37 citations

Mechanisms of Stimulus—Response Coupling in Platelets

1986 • 36 citations

Collagen increases cytoplasmic free calcium in human platelets

1986 • 29 citations

Thrombin induces the rapid formation of inositol bisphosphate and inositol trisphosphate in human platelets

1985 • 23 citations

Immunoglobulin G Fc receptors of human leukocytes

1987 • 19 citations