Thrombin induces the rapid formation of inositol bisphosphate and inositol trisphosphate in human platelets

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Phosphorus Assay in Column Chromatography

1959 • 12,895 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol

1983 • 1,104 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

1983 • 705 citations

The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane

1982 • 541 citations

The stimulation of inositol lipid metabolism that accompanies calcium mobilization in stimulated cells: defined characteristics and unanswered questions

1981 • 518 citations

Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets.

1983 • 394 citations

Phospholipid Metabolism in Stimulated Human Platelets

1980 • 367 citations

Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.

1984 • 358 citations

Rapid decrease of phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets.

1982 • 323 citations

Phospholipid degradation and signal translation for protein phosphorylation

1983 • 323 citations

Inositol trisphosphates in carbachol-stimulated rat parotid glands

1984 • 296 citations

Stimulation of phosphatidic acid production in platelets precedes the formation of arachidonate and parallels the release of serotonin

1979 • 285 citations

Acetylcholine increases the breakdown of triphosphoinositide of rabbit iris muscle prelabelled with [32P] phosphate

1977 • 256 citations

Myo-inositol Phosphates Obtained by Alkaline Hydrolysis of Beef Brain Phosphoinositide

1961 • 217 citations

Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation.

1983 • 205 citations

Formation of lysophosphatidylinositol in platelets stimulated with thrombin or ionophore A23187.

1982 • 201 citations

Specificity of inositol trisphosphate-induced calcium release from permeabilized Swiss-mouse 3T3 cells

1984 • 190 citations

Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change.

1984 • 142 citations

A role for cyclooxygenase products in the formation of phosphatidic acid in stimulated human platelets. Differential mechanisms of action of thrombin and collagen.

1983 • 135 citations

Mechanism of photoinactivation and re-activation in the bioluminescence system of the ctenophore Mnemiopsis

1984 • 111 citations

Complete Characterization of the Myo-inositol Polyphosphates from Beef Brain Phosphoinositide

1961 • 102 citations

Calcium-dependent turnover of brain polyphosphoinositides in vitro after prelabelling in vivo

1981 • 92 citations

Effect of ADP‐induced Shape Change on Incorporation of ³²P into Platelet Phosphatidic Acid and Mono‐, Di‐ and Triphosphatidyl Inositol

1973 • 88 citations

The role of phospholipase C in platelet responses

1983 • 79 citations

Properties and distribution of phosphatidylinositol-specific phospholipase c in human and horse platelets

1983 • 70 citations

Inositol cyclic phosphate as a product of phosphatidylinositol breakdown by phospholipase C (Bacillus cereus)

1975 • 25 citations