Diacylglycerol and phorbol ester stimulate secretion without raising cytoplasmic free calcium in human platelets

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

1962 • 4,273 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Stimulus‐secretion coupling: the concept and clues from chromaffin and other cells

1968 • 1,393 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

Cytoplasmic free Ca²⁺ in human platelets: Ca²⁺ thresholds and Ca‐independent activation for shape‐change and secretion

1982 • 537 citations

Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets.

1983 • 394 citations

A role of calcium-activated phospholipid-dependent protein kinase in human platelet activation. Comparison of thrombin and collagen actions.

1983 • 368 citations

Phospholipid Metabolism in Stimulated Human Platelets

1980 • 367 citations

Cooperative roles of various membrane phospholipids in the activation of calcium-activated, phospholipid-dependent protein kinase.

1981 • 367 citations

Calcium control of exocytosis and endocytosis in bovine adrenal medullary cells

1981 • 250 citations

Biochemistry of Neurotransmitter Release

1979 • 237 citations

Phosphatidylinositol turnover in platelet activation; Calcium mobilization and protein phosphorylation

1982 • 193 citations

EFFECTS OF EXTRACELLULAR CA⁺⁺AND MG⁺⁺ON CYTOSOLIC CA⁺⁺AND PTH RELEASE IN DISPERSED BOVINE PARATHYROID PETI

1983 • 139 citations

Evidence that Calcium Regulates Platelet Function

1978 • 129 citations

THE TUMOR-PROMOTER PHORBOL ESTER (12-0-TETRADECANOYL-PHORBOL-13-ACETATE), A POTENT AGGREGATING AGENT FOR BLOOD PLATELETS

1974 • 113 citations

Insulinotropic effect of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate in rat pancreatic islets.

1980 • 106 citations

Platelets: Cellular Response Mechanisms and their Biological Significance

1981 • 102 citations

Agonist selectivity and second messenger concentration in Ca2+-mediated secretion

1982 • 100 citations

Investigation of the release reaction in platelets exposed to phorbol myristate acetate.

1974 • 93 citations

Effects of Calcium Ionophores on the Synthesis and Release of Parathyroid Hormone

1977 • 61 citations

Stimulated inositol lipid metabolism: An introduction

1982 • 59 citations

Inositol lipid metabolism in the responses of stimulted platelets

1982 • 58 citations

Synthesis of C‐18 mixed acid diacyl‐sn‐glycerol enantiomers

1971 • 49 citations

Norepinephrine causes alpha 1-adrenergic receptor-mediated decrease of phosphatidylinositol in isolated rat liver plasma membranes supplemented with cytosol.

1983 • 48 citations

Inositol lipids and cell stimulation in mammalian salivary gland

1982 • 40 citations

5-Hydroxytryptamine stimulation of phosphatidylinositol hydrolysis and calcium signalling in the blowfly salivary gland

1982 • 28 citations

Effects of phorbol ester tumor promoters in platelet aggregation and platelet production of cyclooxygenase products.

1979 • 12 citations

The role of calcium in macrophage chemotaxis to the phorbol ester tumor promoter TPA

1982 • 9 citations