Thymocyte Fas Expression Is Dysregulated in Myasthenia Gravis Patients With Anti-Acetylcholine Receptor Antibody

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1995 • 1,662 citations

Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

1994 • 1,558 citations

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

1995 • 1,549 citations

Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1995 • 1,477 citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

1995 • 1,346 citations

Mutations in Fas Associated with Human Lymphoproliferative Syndrome and Autoimmunity

1995 • 1,306 citations

Antibody to acetylcholine receptor in myasthenia gravis

1998 • 1,149 citations

Antibody to acetylcholine receptor in myasthenia gravis: Prevalence, clinical correlates, and diagnostic value

1976 • 1,123 citations

Protection from Fas-Mediated Apoptosis by a Soluble Form of the Fas Molecule

1994 • 1,120 citations

T-cell apoptosis detected in situ during positive and negative selection in the thymus

1994 • 1,071 citations

Fas and Fas ligand: lpr and gld mutations

1995 • 906 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Negative selection of lymphocytes

1994 • 810 citations

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1994 • 708 citations

Thymic hyperplasia and neoplasia: A review of current concepts

1978 • 595 citations

Differential expression of apoptosis-related Fas antigen on lymphocyte subpopulations in human peripheral blood.

1992 • 510 citations

Activation interferes with the APO-1 pathway in mature human T cells

1993 • 466 citations

DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement

1992 • 392 citations

T helper type 1/T helper type 2 cytokines and T cell death: preventive effect of interleukin 12 on activation-induced and CD95 (FAS/APO-1)-mediated apoptosis of CD4+ T cells from human immunodeficiency virus-infected persons.

1995 • 283 citations

An assay for antibodies to human acetylcholine receptor in serum from patients with myasthenia gravis

1977 • 283 citations

Reentry of T cells to the adult thymus is restricted to activated T cells.

1991 • 263 citations

Enhanced and accelerated lymphoproliferation in Fas-null mice.

1996 • 211 citations

The apoptosis-1/Fas protein in human systemic lupus erythematosus.

1994 • 200 citations

Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody.

1995 • 197 citations

Myasthenic thymus and thymoma are selectively enriched in acetylcholine receptor–reactive T cells

1990 • 153 citations

The Role of the Thymus in Myasthenia Gravis: Immunohistological and Immunological Studies in 115 Cases^a

1987 • 119 citations

The selection of the α,β heterodimeric T-cell receptor for antigen

1986 • 100 citations

Up-regulated expression of Fas antigen (CD95) by peripheral naive and memory T cell subsets in patients with systemic lupus erythematosus (SLE): a possible mechanism for lymphopenia

1995 • 98 citations

Origin of CD4-CD8-B220+ T cells in MRL-lpr/lpr mice. Clues from a T cell receptor beta transgenic mouse.

1993 • 98 citations

Involvement of apoptosis antigen Fas in clonal deletion of human thymocytes

1994 • 97 citations

Expression and Function of Fas Antigen and bcl-2 in Human Systemic Lupus Erythematosus Lymphocytes

1994 • 93 citations

Thymic B cells from myasthenia gravis patients are activated B cells. Phenotypic and functional analysis.

1990 • 90 citations

Thymectomy for Myasthenia Gravis: Recent Observations and Comparisons With Past Experience

1989 • 89 citations

Levels of soluble fas/APO‐1 /CD95 in systemic lupus erythematosus and juvenile rheumatoid arthritis

1995 • 84 citations

Anti‐AChR antibodies, thymic histology, and T cell subsets in myasthenia gravis

1984 • 83 citations

The APO‐1/Fas (CD95) receptor is expressed in homozygous MRL/lpr mice

1994 • 70 citations

Differential expression of APO‐1 on human thymocytes: Implications for negative selection?

1994 • 67 citations

Autoimmune T lymphocytes in myasthenia gravis. Determination of target epitopes using T lines and recombinant products of the mouse nicotinic acetylcholine receptor gene.

1989 • 65 citations

Lack of correlation between serum soluble fas/APO‐1 levels and autoimmune disease

1995 • 63 citations

Anti-acetylcholine receptor antibodies decrease after thymectomy in patients with myasthenia gravis. Clinical correlations

1991 • 55 citations

In situ production of interleukins in hyperplastic thymus from myasthenia gravis patients

1991 • 53 citations

Cell types required for anti-acetylcholine receptor antibody synthesis by cultured thymocytes and blood lymphocytes in myasthenia gravis.

1984 • 50 citations

The role of the thymus in myasthenia gravis

1994 • 46 citations

6th international congress of immunology

1985 • 41 citations

Myasthenia gravis: effect of thymectomy in 425 patients A 15-year experience

1990 • 41 citations

Myasthenia gravis

1991 • 34 citations

In vitro anti-acetylcholine receptor antibody synthesis by myasthenia gravis patient lymphocytes: Correlations with thymic histology and thymic epithelial-cell interactions

1987 • 33 citations

Evidence of enhanced recombinant interleukin-2 sensitivity in thymic lymphocytes from patients with myasthenia gravis: possible role in autoimmune pathogenesis

1989 • 32 citations

T-cell antigenic sites involved in Myasthenia Gravis: Correlations with antibody titre and disease severity

1991 • 25 citations

Synergy between T Cell Receptor and Fas (CD95/APO-1) Signaling in Mouse Thymocyte Death

1996 • 20 citations

Reduced expression of apoptosis-related antigens in thymuses from patients with myasthenia gravis

1994 • 18 citations

Antibodies to acetylcholine receptors in myasthenia gravis. In vitro synthesis by peripheral blood lymphocytes before and after thymectomy

1992 • 8 citations

T‐Cell Receptor Expression in the Thymus from Patients with Myasthenia Gravis^a

1995 • 5 citations

Antibodies to Acetylcholine Receptors in Myasthenia Gravis

1989 • 4 citations