Induction of an aging mRNA retinal pigment epithelial cell phenotype by matrix-containing advanced glycation end products in vitro.

Cluster analysis and display of genome-wide expression patterns

1998 • 16,410 citations

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications

1988 • 2,527 citations

Activating Smoothened mutations in sporadic basal-cell carcinoma

1998 • 1,327 citations

ARPE-19, A Human Retinal Pigment Epithelial Cell Line with Differentiated Properties

1996 • 1,254 citations

Apoptosis signaling by death receptors

1998 • 976 citations

Advanced glycation end products contribute to amyloidosis in Alzheimer disease.

1994 • 791 citations

Stimulation of Fibroblast Cell Growth, Matrix Production, and Granulation Tissue Formation by Connective Tissue Growth Factor

1996 • 754 citations

Connective tissue growth factor: a mediator of TGF-β action on fibroblasts

1997 • 743 citations

Gene expression profiles of laser-captured adjacent neuronal subtypes

1999 • 708 citations

Oxidative damage and protection of the RPE

2000 • 616 citations

Expression of connective tissue growth factor in human renal fibrosis

1998 • 545 citations

Immunochemical detection of advanced glycosylation end products in vivo.

1992 • 496 citations

Dishevelled Proteins Lead to Two Signaling Pathways

1999 • 291 citations

p53 and apoptosis

1998 • 282 citations

Cell proliferation control by Notch signaling in Drosophila development

1998 • 269 citations

Apoptosis Induced by Transforming Growth Factor-β in Fetal Hepatocyte Primary Cultures

1996 • 262 citations

Glycation-induced inactivation and loss of antigenicity of catalase and superoxide dismutase

1997 • 257 citations

Reducing sugars trigger oxidative modification and apoptosis in pancreatic β-cells by provoking oxidative stress through the glycation reaction

1996 • 254 citations

Presenilins, the Endoplasmic Reticulum, and Neuronal Apoptosis in Alzheimer's Disease

1998 • 247 citations

Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis

1998 • 242 citations

Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.

1999 • 233 citations

Site-specific and random fragmentation of Cu,Zn-superoxide dismutase by glycation reaction. Implication of reactive oxygen species.

1992 • 227 citations

Advanced Glycation End-products and Atherosclerosis

1996 • 206 citations

MMP-2: Expression, Activation and Inhibition

1996 • 195 citations

Altered cellular interactions between endothelial cells and nonenzymatically glucosylated laminin/type IV collagen.

1992 • 190 citations

5 Cellular Mechanisms of Wingless/Wnt Signal Transduction

1998 • 174 citations

Role of transforming growth factor-beta in transdifferentiation and fibrosis of lens epithelial cells.

1999 • 171 citations

Characteristics of Drusen and Bruch's Membrane in Postmortem Eyes With Age-Related Macular Degeneration

1997 • 161 citations

Transforming Growth Factor Beta 2 is the Predominant Isoform in the Neural Retina, Retinal Pigment Epithelium-Choroid and Vitreous of the Monkey Eye

1994 • 137 citations

Analysis of segmental renal gene expression by laser capture microdissection

2000 • 107 citations

Cycloheximide prevents apoptosis, reactive oxygen species production, and glutathione depletion induced by transforming growth factor ? in fetal rat hepatocytes in primary culture

1997 • 105 citations

Identification of Glycosylated 38-kDa Connective Tissue Growth Factor (IGFBP-Related Protein 2) and Proteolytic Fragments in Human Biological Fluids, and Up-Regulation of IGFBP-rP2 Expression by TGF-β in Hs578T Human Breast Cancer Cells

1998 • 98 citations

Advanced glycation end products induce apoptosis and procoagulant activity in cultured human umbilical vein endothelial cells

1999 • 97 citations

pannier acts upstream of wingless to direct dorsal eye disc development in Drosophila

2000 • 89 citations

Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.

1999 • 80 citations

DNA cleavage induced by glycation of Cu, Zn-superoxide dismutase

1994 • 77 citations

Apoptosis in Proliferative Vitreoretinal Disorders: Possible Involvement of TGF-β-induced RPE cell Apoptosis

1997 • 64 citations

Analysis of anterior pituitary hormone mRNA expression in immunophenotypically characterized single cells after laser capture microdissection.

1999 • 58 citations

The Advanced Glycation Endproduct Pentosidine Induces the Expression of PDGF-B in Human Retinal Pigment Epithelial Cells

1998 • 58 citations

Patched (ptch)-associated preferential expression of smoothened (smoh) in human basal cell carcinoma of the skin.

1997 • 51 citations

Tissue-Specific Regulation of Vein/EGF Receptor Signaling in Drosophila

1999 • 46 citations

Oxidative stress caused by glycation of Cu, Zn-superoxide dismutase and its effects on intracellular components

1996 • 38 citations

Differential Expression Pattern of the Three Fringe Genes is Associated with Epidermal Differentiation

1998 • 35 citations

Effect of Matrix Glycation on Expression of Type IV Collagen, MMP-2, MMP-9 and TIMP-1 by Human

1996 • 35 citations

Inhibition of Endothelial Cell Differentiation on a Glycosylated Reconstituted Basement Membrane Complex

1996 • 34 citations

cDNA Cloning of a Humandishevelled DVL-3Gene, Mapping to 3q27, and Expression in Human Breast and Colon Carcinomas

1997 • 30 citations

Isolation, characterization and chromosomal localization of human WNT10B

1997 • 29 citations

Glycated Proteins Modulate Tissue–Plasminogen Activator-Catalyzed Plasminogen Activation

1997 • 25 citations

Identification of EPS8 as a Dvl1-Associated Molecule

1999 • 22 citations

EAST, a novel EGF receptor substrate, associates with focal adhesions and actin fibers

1998 • 16 citations

CD 95 expression in traumatic proliferative vitreoretinopathy: a target for the induction of apoptosis.

1996 • 10 citations