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The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis

Data up to Jan 2025

Published1994
Citations295
References54

Total Citations Per Year

Abstract

References (54)

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tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors.

1992 • 410 citations

Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors

1993 • 392 citations

The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.

1989 • 363 citations

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1989 • 358 citations

Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia.

1990 • 350 citations

The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein.

1990 • 347 citations

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1990 • 316 citations

Disruption of the Human SCL Locus by "Illegitimate" V-(D)-J Recombinase Activity

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Expression of a MyoD family member prefigures muscle pattern in Drosophila embryos.

1990 • 243 citations

The SCL gene product: a positive regulator of erythroid differentiation.

1992 • 238 citations

Expression of tal-1 and GATA-binding proteins during human hematopoiesis

1993 • 233 citations

Embryonic and fetal hemopoiesis: an overview.

1991 • 230 citations

Angioblast differentiation and morphogenesis of the vascular endothelium in the mouse embryo

1991 • 181 citations

Differential expression of the LYL, SCL and E2A helix-loop-helix genes within the hemopoietic system.

1991 • 161 citations

DIFFERENTIATION REQUIRES CONTINUOUS ACTIVE CONTROL

1992 • 158 citations

Enhancer-Binding Activity of the tal-1 Oncoprotein in Association with the E47/E12 Helix-Loop-Helix Proteins

1991 • 156 citations

SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain.

1992 • 148 citations

Splenic erythroblasts in anemia‐inducing friend disease: A source of cells for studies of erythropoietin‐mediated differentiation

1984 • 146 citations

Molecular characterization of NSCL, a gene encoding a helix-loop-helix protein expressed in the developing nervous system.

1992 • 135 citations

Enhanced expression of the tie receptor tyrosine kinase in endothelial cells during neovascularization

1992 • 132 citations

Differential antero-posterior expression of two proteins encoded by a homeobox gene in Xenopus and mouse embryos.

1988 • 121 citations

Erythroid expression of the 'helix-loop-helix' gene, SCL.

1991 • 106 citations

Embryonic angiogenesis factors

1991 • 103 citations

Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia.

1990 • 90 citations

The helix‐loop‐helix domain: A common motif for bristles, muscles and sex

1991 • 89 citations

Molecular cloning and chromosomal localization of the murine homolog of the human helix-loop-helix gene SCL.

1991 • 81 citations

c-tal, a helix-loop-helix protein, is juxtaposed to the T-cell receptor- beta chain gene by a reciprocal chromosomal translocation: t(1;7)(p32;q35)

1991 • 66 citations

Disruption of the SCL gene by a t(1;3) translocation in a patient with T cell acute lymphoblastic leukemia.

1992 • 61 citations

NSCL-2: a basic domain helix-loop-helix gene expressed in early neurogenesis.

1992 • 59 citations

HEN1 and HEN2: a subgroup of basic helix-loop-helix genes that are coexpressed in a human neuroblastoma.

1992 • 57 citations

Disruption of the SCL locus in T-lymphoid malignancies correlates with commitment to the T-cell receptor alpha beta lineage

1992 • 56 citations

A third tal-1 promoter is specifically used in human T cell leukemias.

1992 • 54 citations

Translocations that highlight chromosomal regions of differentiated activity

1985 • 53 citations

Target cells for friend virus-induced erythroid bursts in vitro

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Transcription control and differentiation: the HLH family, c-myc and C/EBP

1989 • 26 citations

Molecular cloning of the chicken SCL cDNA

1992 • 16 citations

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The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular… (1994) – Blood | Metascience Observatory Explorer