Cell interactions and gene interactions in peripheral neurogenesis.

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

The FLP recombinase of yeast catalyzes site-specific recombination in the drosophila genome

1989 • 939 citations

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

1991 • 770 citations

The choice of cell fate in the epidermis of Drosophila

1991 • 736 citations

The achaete-scute gene complex of D. melanogaster: Conserved Domains in a subset of genes required for neurogenesis and their homology to myc

1987 • 501 citations

Notch is required for successive cell decisions in the developing Drosophila retina.

1989 • 473 citations

Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc.

1991 • 444 citations

daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex

1988 • 442 citations

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors.

1986 • 427 citations

extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins

1990 • 407 citations

Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing.

1991 • 390 citations

The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein

1990 • 387 citations

Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila

1991 • 372 citations

A dual function of the Notch gene in Drosophila sensillum development

1990 • 333 citations

The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats

1987 • 317 citations

Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila

1990 • 316 citations

Local and General Factors in the Development of “Pattern” in Rhodnius Prolixus (Hemiptera)

1940 • 309 citations

Genesis of the Drosophila peripheral nervous system

1989 • 289 citations

Molecular genetics of the achaete-scute gene complex of D. melanogaster

1985 • 287 citations

Closely related transcripts encoded by the neurogenic gene complex enhancer of split of Drosophila melanogaster.

1989 • 274 citations

The achaete-scute gene complex of Drosophila melanogaster comprises four homologous genes.

1988 • 271 citations

The making of a fly

1992 • 258 citations

The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes

1991 • 257 citations

Delta, a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factor of vertebrates.

1988 • 251 citations

GENETIC ANALYSIS OF THE ACHAETE-SCUTE SYSTEM OF DROSOPHILA MELANOGASTER

1979 • 247 citations

Expression of achaete and scute genes in Drosophila imaginal discs and their function in sensory organ development.

1989 • 246 citations

Cell autonomy of lin-12 function in a cell fate decision in C. elegans

1989 • 241 citations

Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila.

1991 • 238 citations

The emergence of sense organs in the wing disc of Drosophila

1991 • 237 citations

Chromosomal Deficiencies and the Embryonic Development of Drosophila Melanogaster

1937 • 235 citations

A role for the Drosophila neurogenic genes in mesoderm differentiation

1991 • 235 citations

Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus

1987 • 217 citations

Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo

1992 • 211 citations

A deduced gene product from the Drosophila neurogenic locus, Enhancer of split, shows homology to mammalian G-protein β subunit

1988 • 197 citations

Molecular analysis of the asense gene, a member of the achaete-scute complex of Drosophila melanogaster, and its novel role in optic lobe development.

1989 • 178 citations

Competence to develop sensory organs is temporally and spatially regulated in Drosophila epidermal primordia.

1990 • 174 citations

DEVELOPMENTAL ANALYSIS OF THE ACHAETE-SCUTE SYSTEM OF DROSOPHILA MELANOGASTER

1978 • 173 citations

Lateral inhibition and cell fate during neurogenesis in Drosophila: the interactions between scute, Notch and Delta

1990 • 159 citations

The embryonic expression of the Notch locus of Drosophila melanogaster and the implications of point mutations in the extracellular EGF-like domain of the predicted protein.

1987 • 157 citations

An early embryonic product of the gene shaggy encodes a serine/threonine protein kinase related to the CDC28/cdc2+ subfamily.

1990 • 154 citations

The Expression of Neurogenic Loci in Imaginal Epidermal Cells of Drosophila Melanogaster

1984 • 146 citations

Independent subpatterns of sense organs require independent genes of the achaete-scute complex in Drosophila larvae

1987 • 144 citations

Excess function Hairy-wing mutations caused by gypsy and copia insertions within structural genes of the achaete-scute locus of Drosophila

1986 • 139 citations

Gene-dose titration analysis in the search of trans-regulatory genes in Drosophila.

1982 • 134 citations

Mutations of early neurogenesis inDrosophila

1981 • 121 citations

Enhancer of splitD, a dominant mutation of Drosophila, and its use in the study of functional domains of a helix-loop-helix protein.

1992 • 117 citations

The extramacrochaetae gene provides information for sensory organ patterning.

1992 • 115 citations

Single amino acid substitutions in EGF-like elements of notch and delta modify drosophila development and affect cell adhesion in vitro

1992 • 113 citations

Deletion analysis of the achaete-scute locus of Drosophila melanogaster.

1987 • 111 citations

Cross-Regulatory Interactions Between the Proneural achaete and scute Genes of Drosophila

1991 • 108 citations

The expression and role of a proneural gene, achaete, in the development of the larval nervous system of Drosophila.

1993 • 103 citations

A unitary basis for different Hairy-wing mutations of Drosophila melanogaster.

1988 • 90 citations

The determination of sense organs in Drosophila: effect of the neurogenic mutations in the embryo

1991 • 88 citations

ALLELIC NEGATIVE COMPLEMENTATION AT THE ABRUPTEX LOCUS OF DROSOPHILA MELANOGASTER

1975 • 88 citations

NEGATIVE COMPLEMENTATION AT THE NOTCH LOCUS OF DROSOPHILA MELANOGASTER

1975 • 79 citations

Cell-autonomous role of Notch, an epidermal growth factor homologue, in sensory organ differentiation in Drosophila.

1991 • 72 citations

Genetic analysis ofHairy-wing mutations

1986 • 61 citations

Developmental genetics of the wing vein pattern of Drosophila

1989 • 23 citations

Two different sets of cis elements regulate scute to establish two different sensory patterns

1989 • 23 citations