Expression of tal-1 and GATA-binding proteins during human hematopoiesis

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

GATA-binding transcription factors in hematopoietic cells

1992 • 845 citations

Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.

1990 • 629 citations

The erythroid-specific transcription factor eryf1: A new finger protein

1989 • 608 citations

Expression of an erythroid transcription factor in megakaryocytic and mast cell lineages

1990 • 481 citations

Megakaryocytic and erythrocytic lineages share specific transcription factors

1990 • 446 citations

Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells

1988 • 406 citations

Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene.

1991 • 364 citations

The gene SCL is expressed during early hematopoiesis and encodes a differentiation-related DNA-binding motif.

1989 • 363 citations

Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia.

1990 • 350 citations

The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein.

1990 • 347 citations

Transcriptional regulation by dimerization: Two sides to an incestuous relationship

1990 • 343 citations

Disruption of the Human SCL Locus by "Illegitimate" V-(D)-J Recombinase Activity

1990 • 301 citations

Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells.

1992 • 295 citations

Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript.

1989 • 285 citations

Purification of human blood burst‐forming units‐erythroid and demonstration of the evolution of erythropoietin receptors

1990 • 241 citations

Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.

1989 • 227 citations

A T-cell specific TCR delta DNA binding protein is a member of the human GATA family.

1991 • 178 citations

Differential expression of the LYL, SCL and E2A helix-loop-helix genes within the hemopoietic system.

1991 • 161 citations

Enhancer-Binding Activity of the tal-1 Oncoprotein in Association with the E47/E12 Helix-Loop-Helix Proteins

1991 • 156 citations

Involvement of the putative hematopoietic transcription factor SCL in T- cell acute lymphoblastic leukemia

1992 • 140 citations

Two site-specific deletions and t(1;14) translocation restricted to human T-cell acute leukemias disrupt the 5' part of the tal-1 gene.

1991 • 133 citations

Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T‐cell leukemias

1990 • 127 citations

Interleukin-6 and its receptor are expressed by human megakaryocytes: in vitro effects on proliferation and endoreplication

1991 • 123 citations

Structural characterization of SIL, a gene frequently disrupted in T-cell acute lymphoblastic leukemia.

1991 • 113 citations

The SCL Gene Is Formed from a Transcriptionally Complex Locus

1990 • 101 citations

The t(1;14)(p34;q11) is nonrandom and restricted to T-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study

1990 • 99 citations

Coding sequences of the tal-1 gene are disrupted by chromosome translocation in human T cell leukemia.

1990 • 90 citations

Antisense SCL suppresses self-renewal and enhances spontaneous erythroid differentiation of the human leukaemic cell line K562.

1991 • 89 citations

In vitro effects of hematopoietic growth factors on the proliferation, endoreplication, and maturation of human megakaryocytes

1991 • 73 citations

c-tal, a helix-loop-helix protein, is juxtaposed to the T-cell receptor- beta chain gene by a reciprocal chromosomal translocation: t(1;7)(p32;q35)

1991 • 66 citations

A third tal-1 promoter is specifically used in human T cell leukemias.

1992 • 54 citations

Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression.

1991 • 49 citations

Effects of five recombinant hematopoietic growth factors on enriched human erythroid progenitors in serum‐replaced cultures

1989 • 18 citations

c-jun and c-fos are expressed by human megakaryocytes.

1992 • 15 citations