TGF-β signaling

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

1997 • 2,174 citations

TOR, a Central Controller of Cell Growth

2000 • 1,919 citations

New insights into TGF-β–Smad signalling

2004 • 1,169 citations

[Genetics of Caenorhabditis elegans].

1989 • 905 citations

The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans

1975 • 881 citations

A transcriptional partner for MAD proteins in TGF-β signalling

1996 • 699 citations

The TOR pathway interacts with the insulin signaling pathway to regulateC. eleganslarval development, metabolism and life span

2004 • 682 citations

The Caenorhabditis elegans dauer larva: Developmental effects of pheromone, food, and temperature

1984 • 594 citations

The Caenorhabditis elegans male: Postembryonic development of nongonadal structures

1980 • 588 citations

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

2003 • 548 citations

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components.

1996 • 528 citations

Control of C. elegans Larval Development by Neuronal Expression of a TGF-β Homolog

1996 • 516 citations

TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation

2001 • 514 citations

Interacting genes in nematode dauer larva formation

1981 • 504 citations

Inducible Antibacterial Defense System in C. elegans

2002 • 462 citations

Interaction and Functional Cooperation of PEBP2/CBF with Smads

1999 • 449 citations

Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-β Receptor Activity

2002 • 397 citations

The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development

1993 • 368 citations

Regulation of Body Size and Behavioral State of C. elegans by Sensory Perception and the EGL-4 cGMP-Dependent Protein Kinase

2002 • 344 citations

Chemosensory Neurons Function in Parallel to Mediate a Pheromone Response in C. elegans

1996 • 311 citations

daf-1, a C. elegans gene controlling dauer larva development, encodes a novel receptor protein kinase

1990 • 293 citations

Evidence for parallel processing of sensory information controlling dauer formation in Caenorhabditis elegans.

1993 • 262 citations

Smad2 Nucleocytoplasmic Shuttling by Nucleoporins CAN/Nup214 and Nup153 Feeds TGFβ Signaling Complexes in the Cytoplasm and Nucleus

2002 • 252 citations

Pioneer Axon Guidance by UNC-129, a C. elegans TGF-β

1998 • 229 citations

Cuticle collagen genes

2000 • 212 citations

The Cyclic GMP-Dependent Protein Kinase EGL-4 Regulates Olfactory Adaptation in C. elegans

2002 • 205 citations

Molecular Evolution of a Developmental Pathway: Phylogenetic Analyses of Transforming Growth Factor-β Family Ligands, Receptors and Smad Signal Transducers

1999 • 175 citations

Suppressors of Ectopic UNC-5 Growth Cone Steering Identify Eight Genes Involved in Axon Guidance inCaenorhabditis elegans

1998 • 175 citations

Somatic polyploidization and cellular proliferation drive body size evolution in nematodes

2000 • 155 citations

Targets of TGF-β Signaling in Caenorhabditis elegans Dauer Formation

2000 • 155 citations

Systematic Interactome Mapping and Genetic Perturbation Analysis of a C. elegans TGF-β Signaling Network

2004 • 139 citations

Analysis of Smad nucleocytoplasmic shuttling in living cells

2004 • 135 citations

Nucleocytoplasmic Shuttling of Smad1 Conferred by Its Nuclear Localization and Nuclear Export Signals

2001 • 114 citations

DAF-5 is a Ski oncoprotein homolog that functions in a neuronal TGFβpathway to regulateC. elegansdauer development

2003 • 104 citations

Cyclic GMP-dependent protein kinase EGL-4 controls body size and lifespan inC. elegans

2003 • 100 citations

Identification of transforming growth factor-β- regulated genes in Caenorhabditis elegans by differential hybridization of arrayed cDNAs

1999 • 100 citations

A Caenorhabditis elegans TGF-beta, DBL-1, controls the expression of LON-1, a PR-related protein, that regulates polyploidization and body length

2002 • 99 citations

UNC-52/Perlecan affects gonadal leader cell migrations in c. elegans hermaphrodites through alterations in growth factor signaling

2003 • 85 citations

Hypodermal Expression of Caenorhabditis elegans TGF-β Type I Receptor SMA-6 Is Essential for the Growth and Maintenance of Body Length

2001 • 70 citations

TheCaenorhabditis elegans schnurrihomologsma-9mediates stage- and cell type-specific responses to DBL-1 BMP-related signaling

2003 • 66 citations

lon-1 Regulates Caenorhabditis elegans Body Size Downstream of the dbl-1 TGFβ Signaling Pathway

2002 • 65 citations

Genetic screen for small body size mutants in C. elegans reveals many TGFβ pathway components

2003 • 63 citations

Expression Pattern, Regulation, and Biological Role of Runt Domain Transcription Factor, run, in Caenorhabditis elegans

2002 • 59 citations

Integration of Semaphorin-2A/MAB-20, ephrin-4, and UNC-129 TGF-β Signaling Pathways Regulates Sorting of Distinct Sensory Rays in C. elegans

2004 • 48 citations

SMA-3 Smad Has Specific and Critical Functions in DBL-1/SMA-6 TGFβ-Related Signaling

2000 • 44 citations

Mechanisms for the control of body size by a G‐kinase and a downstream TGFβ signal pathway in Caenorhabditis elegans

2004 • 30 citations

A DAF-1-binding protein BRA-1 is a negative regulator of DAF-7 TGF-β signaling

2001 • 28 citations

RNT-1, the C. elegans homologue of mammalian RUNX transcription factors, regulates body size and male tail development

2004 • 26 citations

TGFβ-like Signaling and Spicule Development in Caenorhabditis elegans

1999 • 23 citations

cGMP and a germ‐line signal control body size in C. elegans through cGMP‐dependent protein kinase EGL‐4

2004 • 19 citations

cDNA cloning of run, a Caenorhabditis elegans Runt domain encoding gene

2000 • 19 citations

Expression of the C. elegans labial orthologue ceh-13 during male tail morphogenesis

2003 • 16 citations

Alternative Polyadenylation Results in a Truncated daf-4 BMP Receptor That Antagonizes DAF-7-mediated Development in Caenorhabditis elegans

2004 • 9 citations