Kinetic analysis of the heparin-enhanced plasmin–antithrombin III reaction. Apparent catalytic role of heparin

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor

1973 • 1,363 citations

PARTIAL PURIFICATION AND PROPERTIES OF A PROTEOLYTIC ENZYME OF HUMAN SERUM

1949 • 299 citations

The molecular-weight-dependence of the anti-coagulant activity of heparin

1978 • 273 citations

Binding of low-affinity and high-affinity heparin to antithrombin. Ultraviolet difference spectroscopy and circular dichroism studies

1978 • 140 citations

A catalytic role for heparin

1978 • 128 citations

Structure-function relationships of heparin species

1978 • 126 citations

Binding of heparin to human antithrombin III as studied by measurements of tryptophan fluorescence

1977 • 114 citations

Mechanism of action of heparin through thrombin on blood coagulation

1975 • 88 citations

Development of Large Scale Fractionation Methods

1979 • 87 citations

Multiplicity of rabbit plasminogen. Physical characterization

1972 • 82 citations

The inactivation of thrombin and plasmin by antithrombin III in the presence of Sepharose-heparin

1977 • 80 citations

Action of heparin on thrombin-antithrombin reaction

1975 • 77 citations

Covalent modification of human alpha-thrombin with pyridoxal 5'-phosphate. Effect of phosphopyridoxylation on the interaction of thrombin with heparin.

1979 • 63 citations

Conformational changes accompanying the binding of antithrombin III to thrombin

1979 • 58 citations

Acrylamide gel electrophoresis of acidic mucopolysaccharides

1969 • 57 citations

The heparin-thrombin complex in the mechanism of thrombin inactivation by heparin

1977 • 56 citations

Role of heparin in the inactivation of thrombin, factor Xa, and plasmin by antithrombin III

1977 • 50 citations

Kinetic analysis of the heparin-enhanced antithrombin III/thrombin reaction. Reaction rate enhancement by heparin-thrombin association.

1979 • 50 citations

Effect of heparin on thrombin inactivation by antithrombin-III

1978 • 47 citations

Effect of heparin modification on its activity in enhancing the inhibition of thrombin by antithrombin III

1977 • 42 citations

Inhibition of the heparin-antithrombin III/thrombin reaction by active site blocked-thrombin

1979 • 33 citations

Decreased Heparin Sensitivity of Cyclohexanedione-Modified Thrombin

1978 • 31 citations

Inactivation of α- and β-thrombin by antithrombin-III, α2-macroglobulin and α1-proteinase inhibitor

1977 • 25 citations

The influence of heparin, NaCl and CaCl2 on the rate of the thrombin-antithrombin III reaction

1979 • 21 citations

Heparin binding to antithrombin III: Variation in binding sites and affinity

1978 • 18 citations

Altered inactivation of trinitrophenylated thrombin by antithrombin iii in the presence of heparin

1980 • 11 citations