The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*

1964 • 18,916 citations

Une micro-méthode de l’immuno-électrophorèse

1955 • 3,859 citations

Isoelectric Fractionation, Analysis, and Characterization of Ampholytes in Natural pH Gradients. IV. Further Studies on the Resolving Power in Connection with Separation of Myoglobins.

1966 • 1,303 citations

Chemical Coupling of Proteins to Agarose

1967 • 981 citations

Chemical Fixation of Enzymes to Cyanogen Halide Activated Polysaccharide Carriers

1971 • 547 citations

THE THROMBOPLASTIC ACTION OF CEPHALIN

1916 • 514 citations

Major Human Erythrocyte Glycoprotein spans the Cell Membrane

1971 • 404 citations

Coupling of glycosaminoglycans to agarose beads (Sepharose 4B)

1971 • 320 citations

[69] Hirudin as an inhibitor of thrombin

1970 • 311 citations

Highly Purified Antithrombin III with Heparin Cofactor Activity Prepared by Disc Electrophoresis

1968 • 274 citations

THE NATURE OF THE BLEEDING IN JAUNDICE

1938 • 249 citations

THE INHIBITION OF BLOOD CLOTTING: AN UNIDENTIFIED SUBSTANCE WHICH ACTS IN CONJUNCTION WITH HEPARIN TO PREVENT THE CONVERSION OF PROTHROMBIN INTO THROMBIN

1939 • 235 citations

The Role of Serine in the Linkage of Heparin to Protein

1965 • 226 citations

Antithrombin III, Antifactor Xa and Heparin

1970 • 200 citations

Identity of Plasma-activated Factor X Inhibitor with Antithrombin III and Heparin Cofactor

1971 • 195 citations

Immunological Studies on Human Antithrombin III

1970 • 176 citations

Statistical analysis in chemistry and the chemical industry

1955 • 170 citations

Structure of N-terminal Fragments of Fibrinogen and Specificity of Thrombin

1967 • 169 citations

Intermolecular Cross-linking of Monomeric Proteins and Cross-linking of Oligomeric Proteins as a Probe of Quaternary Structure

1972 • 167 citations

Biological Properties of the Naturally Occurring Plasma Inhibitor to Activated Factor X

1971 • 164 citations

COMPETITION AMONG TRYPSIN INHIBITORS

1953 • 162 citations

A Rapid Method of preparing Pure Serum Gamma-Globulin

1960 • 147 citations

Purification of Two Progressive Antithrombins of Human Plasma

1967 • 145 citations

SERUM AC-GLOBULIN: FORMATION FROM PLASMA AC-GLOBULIN; ROLE IN BLOOD COAGULATION; PARTIAL PURIFICATION; PROPERTIES; AND QUANTITATIVE DETERMINATION

1948 • 117 citations

Evidence for an ionic binding of lipoprotein lipase to heparin

1971 • 111 citations

THE ACTIVE SITE OF THROMBIN

1958 • 110 citations

An Antithrombin Reaction Related to Prothrombin Activation

1953 • 95 citations

Activity of Bovine Pancreatic Deoxyribonuclease A with Modified Amino Groups

1971 • 93 citations

Resynthesis by Trypsin of the Cleaved Peptide Bond in Modified Soybean Trypsin Inhibitor

1967 • 86 citations

Rabbit Plasma Inhibitor of the Activated Species of Blood Coagulation Factor X

1971 • 84 citations

Modification of arginines in trypsin inhibitors by 1,2-cyclohexanedione

1968 • 84 citations

Multiple Bovine Thrombin Components

1970 • 78 citations

Transformation of active-site lysine in naturally occurring trypsin inhibitors. A basis for a general mechanism for inhibition of proteolytic enzymes

1968 • 62 citations

NEUTRALIZATION OF AUTOPROTHROMBIN C ACTIVITY WITH ANTITHROMBIN

1964 • 53 citations

Quantitative Aspects of Antithrombin and Heparin in Plasma

1956 • 47 citations

Modification of an Arginyl Residue in Pepsin by 2,3-Butanedione

1972 • 42 citations

Über Trypsininhibitoren, III. Modifizierung und Hemmverhalten des spezifischen Trypsininhibitors aus Schweinepankreas — eine im Sauren katalysierbare tryptische Hydrolyse

1968 • 25 citations

The Chemistry of Blood Coagulation

1960 • 24 citations

A study of the complex of trypsin with its pancreatic inhibitor

1968 • 15 citations

Evidence that cocoonase and trypsin interact with soybean trypsin inhibitor at the same reactive site

1970 • 15 citations

Use of reinforced (mylar-backed) cellulose acetate membranes for quantitative radial immunodiffusion.

1972 • 5 citations

The Chemistry of Blood Coagulation.

1958 • 3 citations