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Oxygen Radicals and Hydroperoxides in Mammalian Organs: Aspects of Redox Cycling and Hydrogen Peroxide Metabolism

Data up to Jan 2025

Published1983
Citations15
References170

Total Citations Per Year

Abstract

References (170)

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Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: Relation to glutathione and NAD(P)H:quinone reductase (DT-diaphorase) activity

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Role of hydroxyl radical scavengers dimethyl sulfoxide, alcohols and methional in the inhibition of prostaglandin biosynthesis

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1980 • 164 citations

Alloxan toxicity to the pancreatic B-cell

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Generation of superoxide anion as a source of hydrogen peroxide in a reconstituted monooxygenase system

1978 • 155 citations

Role of cytoplasmic thioltransferase in cellular regulation by thiol-disulphide interchange

1980 • 154 citations

A direct electron spin resonance and spin-trapping investigation of peroxyl free radical formation by hematin/hydroperoxide systems.

1983 • 149 citations

Detoxification reactions in isolated hepatocytes. Role of glutathione peroxidase, catalase, and formaldehyde dehydrogenase in reactions relating to N-demethylation by the cytochrome P-450 system.

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The subcellular distribution and some properties of the cytochrome b component of the microbicidal oxidase system of human neutrophils

1979 • 145 citations

Evidence for the occurrence of selenium-independent glutathione peroxidase activity in rat liver microsomes

1981 • 139 citations

Some characteristics of 75Se-P, a selenoprotein found in rat liver and plasma, and comparison of it with selenoglutathione peroxidase

1982 • 136 citations

Pathology of Oxygen Toxicity

1983 • 136 citations

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1982 • 136 citations

Differential effects of sulfhydryl reagents on activation and deactivation of the fat cell hexose transport system.

1976 • 132 citations

The Role of NADH in Uncoupled Microsomal Monoxygenations

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Biological Basis of Detoxication

1983 • 130 citations

Reduced nicotinamide adenine dinucleotide phosphate oxidase in adipocyte plasma membrane and its activation by insulin

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Pathology of oxygen

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Increase in hepatic mixed disulphide and glutathione disulphide levels elicited by paraquat

1982 • 118 citations

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1975 • 116 citations

Effects of 4-hydroxynonenal on isolated hepatocytes. Studies on chemiluminescence response, alkane production and glutathione status

1983 • 109 citations

Singlet Oxygen Formation Detected by Low-Level Chemiluminescence during Enzymatic Reduction of Prostaglandin G2to H2

1983 • 109 citations

Evidence of an ubisemiquinone radical(s) from the NADH-ubiquinone reductase of the mitochondrial respiratory chain.

1983 • 103 citations

Direct spectral evidence of the generation of singlet molecular oxygen (1.DELTA.g) in the reaction of potassium superoxide with water

1981 • 101 citations

Earth's neodymium budget and structure and evolution of the mantle

1981 • 101 citations

Relevance of NADPH depletion and mixed disulphide formation in rat lung to the mechanism of cell damage following paraquat administration

1982 • 101 citations

Spectral evidence for the cytochrome P450 nature of prostacyclin synthetase

1981 • 100 citations

In vivo oxidation of reduced nicotinamide-adenine dinucleotide phosphate by paraquat and diquat in rat lung

1977 • 99 citations

Low-level chemiluminescence of hydroperoxide-supplemented cytochrome c

1980 • 96 citations

The relevance of pentose phosphate pathway stimulation in rat lung to the mechanism of paraquat toxicity

1976 • 95 citations

Glutathione Efflux from Perfused Rat Liver after Phenobarbital Treatment, during Drug Oxidations, and in Selenium Deficiency

1978 • 94 citations

Chemistry of superoxide ion. 4. Singlet oxygen is not a major product of dismutation

1980 • 93 citations

Peroxisomal fatty acid oxidation as detected by H2O2 production in intact perfused rat liver

1981 • 89 citations

Assessment of the kidney function in maintenance of plasma glutathione concentration and redox state in anaesthetized rats

1979 • 89 citations

Free radical mechanisms in autoxidation processes

1981 • 88 citations

Effect of oxygen concentration on the reaction of halothane with cytochrome P450 in liver microsomes and isolated perfused rat liver

1978 • 88 citations

Inhibition of γ-glutamylcysteine synthetase by cystamine; An approach to a therapy of 5-oxoprolinuria (pyroglutamic aciduria)

1977 • 81 citations

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1982 • 79 citations

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1981 • 68 citations

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1980 • 54 citations

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1980 • 52 citations

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1977 • 52 citations

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1980 • 51 citations

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1981 • 38 citations

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The role of glutathione in rat adipocyte pentose phosphate cycle activity

1981 • 27 citations

Cytochrome P450 oxidase activity and its role in NADPH dependent lipid peroxidation

1983 • 26 citations

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1982 • 26 citations

Disulphide Exchange Reactions in the Control of Enzymic Activity

1981 • 26 citations

Superoxide-dependent production of hydroxyl radicals in the presence of iron salts

1982 • 25 citations

Inhibition of p-chloromercuribenzoate- and glucose-induced insulin release in vitro by methylene blue, diamide, and tert-butyl hydroperoxide.

1977 • 25 citations

Inactivation of the β-adrenergic receptor in skeletal muscle by dithiols

1983 • 24 citations

Paraquat-induced alterations of phospholipids and GSSG-release in the isolated perfused rat liver, and the effect of SOD-active copper complexes

1981 • 23 citations

Photobiology of Carotenoid Protection

1982 • 22 citations

Activation of the pyruvate dehydrogenase complex in isolated fat cell mitochondria by hydrogen peroxide and t‐butyl hydroperoxide

1980 • 22 citations

Amino acid-dependent sodium transport in plasma membrane vesicles from rat liver

1981 • 22 citations

Free Radicals in Arylamine Carcinogenesis

1980 • 20 citations

THE MECHANISM OF CYTOCHROME P450 ACTION

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Activation of plant acid phosphatases by oxidized glutathione and dehydroascorbate

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Regulation of Rat Liver Glycogen Synthetase

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The lethal oxidase of leucocytes

1983 • 16 citations

Effects of thiol-reactive agents on amino acid transport by sheep erythrocytes

1980 • 16 citations

Effect of Oxidation of Glutathione and Membrane Thiol Groups on Mitochondrial Functions

1978 • 15 citations

Thioredoxin and thioredoxin reductase in pancreatic islets may participate in diabetogenic free-radical production

1982 • 13 citations

On the geometry of leukocyte NADPH‐oxidase, a membrane flavoenzyme

1983 • 13 citations

Microsomal peroxidase activities—Effect of cumene hydroperoxide on the pyridine nucleotide reduced cytochrome b5 steady state

1980 • 12 citations

Activation by reduced glutathione of methotrexate transport into isolated rat liver cells

1982 • 12 citations

Calorimetric evidence for large entropy changes accompanying intermediate steps of the ATP-driven Ca2+ uptake by sarcoplasmic reticulum.

1982 • 10 citations

Thioltransferases

1980 • 9 citations

Effects of Nitrofurantoin on the Glutathione Redox Status and Related Enzymes in the Isolated, Perfused Rabbit Lung

1982 • 9 citations

Effect of diamide and reduced glutathione on the elevated levels of cyclic AMP in rat pancreatic islets exposed to glucose, p-chloromercuribenzoate and aminophylline

1982 • 5 citations

Se and Non-Se Glutathione Peroxidases: Enzymology and Cell Physiology

1982 • 2 citations

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