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THE MECHANISM OF CYTOCHROME P450 ACTION

Data up to Jan 2025

Published1977
Citations19
References25

Total Citations Per Year

Abstract

References (25)

Resolution of the Cytochrome P-450-containing ω-Hydroxylation System of Liver Microsomes into Three Components

1969 • 573 citations

Evidence for the participation of cytochrome b5 in hepatic microsomal mixed-function oxidation reactions

1971 • 559 citations

Hydroxylation-Induced Migration: The NIH Shift

1967 • 519 citations

Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms.

1975 • 456 citations

Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.

1969 • 275 citations

SPIN-STATE CHANGES IN CYTOCHROME P-450 cam ON BINDING OF SPECIFIC SUBSTRATES

1970 • 266 citations

Camphor binding by Pseudomonas putida cytochrome P-450

1971 • 262 citations

Multiplicity of cytochrome P450 hemoproteins in rat liver microsomes

1974 • 200 citations

Cytochrome P450 as an oxene transferase

1976 • 176 citations

Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450

1974 • 173 citations

Oxygenated cytochrome P-450 and its possible role in enzymic hydroxylation

1971 • 160 citations

The Enzymic Formation of a Methylenedioxyphenyl Derivative Exhibiting an Isocyanide-like Spectrum with Reduced Cytochrome P-450 in Hepatic Microsomes

1971 • 134 citations

The Role of NADH in Uncoupled Microsomal Monoxygenations

1974 • 131 citations

Studies on the Kinetics of Cytochrome P-450 Reduction in Rat Liver Microsomes

1970 • 123 citations

Characterisation of Cytochrome P-450 Species in Rat Liver Microsomes, I. Differences in theO-Dealkylation of 7-Ethoxycoumarin after Pretreatment with Phenobarbital and 3-Methylcholanthrene

1973 • 122 citations

Possible higher valence states of cytochrome P-450 during oxidative reactions

1974 • 96 citations

Ferric porphyrin thiolates. Possible relation to cytochrome P-450 enzymes and the structure of (p-nitrobenzenethiolato)iron(III) protoporphyrin IX dimethylester

1975 • 82 citations

Multiplicity of cytochrome P-450 hemoproteins in rat liver microsomes. Preparation and specificity of an antibody to the hemoprotein induced by phenobarbital.

1975 • 81 citations

Immunochemical evidence for the participation of cytochrome b5 in the NADH synergism of the NADPH-dependent mono-oxidase system of hepatic microsomes

1974 • 77 citations

Formation and binding of carbanions by cytochrome P-450 of liver microsomes.

1973 • 75 citations

The interaction between haem-iron and thiols

1969 • 66 citations

Sedimentation and other properties of the reconstituted liver microsomal mixed-function oxidase system containing cytochrome P-450, reduced triphosphopyridine nucleotide-cytochrome P-450 reductase, and phosphatidylcholine.

1973 • 57 citations

Binding of thiols to microsomal cytochrome P-450

1976 • 43 citations

Microsomal hydroxylation of ethylbenzene. Stereospecificity and the effect of phenobarbital induction

1966 • 39 citations

CYTOCHROME P450 CATALYZED OXENE TRANSFER FROM VARIOUS DONORS

1977 • 4 citations

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