THE MECHANISM OF CYTOCHROME P450 ACTION
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Abstract
References (25)
Resolution of the Cytochrome P-450-containing ω-Hydroxylation System of Liver Microsomes into Three Components
1969 • 573 citations
Evidence for the participation of cytochrome b5 in hepatic microsomal mixed-function oxidation reactions
1971 • 559 citations
Hydroxylation-Induced Migration: The NIH Shift
1967 • 519 citations
Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms.
1975 • 456 citations
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
1969 • 275 citations
SPIN-STATE CHANGES IN CYTOCHROME P-450 cam ON BINDING OF SPECIFIC SUBSTRATES
1970 • 266 citations
Camphor binding by Pseudomonas putida cytochrome P-450
1971 • 262 citations
Multiplicity of cytochrome P450 hemoproteins in rat liver microsomes
1974 • 200 citations
Cytochrome P450 as an oxene transferase
1976 • 176 citations
Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450
1974 • 173 citations
Oxygenated cytochrome P-450 and its possible role in enzymic hydroxylation
1971 • 160 citations
The Enzymic Formation of a Methylenedioxyphenyl Derivative Exhibiting an Isocyanide-like Spectrum with Reduced Cytochrome P-450 in Hepatic Microsomes
1971 • 134 citations
The Role of NADH in Uncoupled Microsomal Monoxygenations
1974 • 131 citations
Studies on the Kinetics of Cytochrome P-450 Reduction in Rat Liver Microsomes
1970 • 123 citations
Characterisation of Cytochrome P-450 Species in Rat Liver Microsomes, I. Differences in theO-Dealkylation of 7-Ethoxycoumarin after Pretreatment with Phenobarbital and 3-Methylcholanthrene
1973 • 122 citations
Possible higher valence states of cytochrome P-450 during oxidative reactions
1974 • 96 citations
Ferric porphyrin thiolates. Possible relation to cytochrome P-450 enzymes and the structure of (p-nitrobenzenethiolato)iron(III) protoporphyrin IX dimethylester
1975 • 82 citations
Multiplicity of cytochrome P-450 hemoproteins in rat liver microsomes. Preparation and specificity of an antibody to the hemoprotein induced by phenobarbital.
1975 • 81 citations
Immunochemical evidence for the participation of cytochrome b5 in the NADH synergism of the NADPH-dependent mono-oxidase system of hepatic microsomes
1974 • 77 citations
Formation and binding of carbanions by cytochrome P-450 of liver microsomes.
1973 • 75 citations
The interaction between haem-iron and thiols
1969 • 66 citations
Sedimentation and other properties of the reconstituted liver microsomal mixed-function oxidase system containing cytochrome P-450, reduced triphosphopyridine nucleotide-cytochrome P-450 reductase, and phosphatidylcholine.
1973 • 57 citations
Binding of thiols to microsomal cytochrome P-450
1976 • 43 citations
Microsomal hydroxylation of ethylbenzene. Stereospecificity and the effect of phenobarbital induction
1966 • 39 citations
CYTOCHROME P450 CATALYZED OXENE TRANSFER FROM VARIOUS DONORS
1977 • 4 citations