Investigation of Genetic Linkage in Human Families

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Linear Statistical Inference and its Applications

1973 • 10,599 citations

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.

1980 • 8,270 citations

The Metabolic Basis of Inherited Disease.

1988 • 7,933 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

THE ESTIMATION OF MAP DISTANCES FROM RECOMBINATION VALUES

1943 • 5,806 citations

The Genetics and Biology of Drosophila

1978 • 3,910 citations

Hypervariable ‘minisatellite’ regions in human DNA

1985 • 3,789 citations

Linear Statistical Inference and Its Applications.

1975 • 3,726 citations

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

Repeated Sequences in DNA

1968 • 2,836 citations

Genetic variations of Drosophila melanogaster

1967 • 2,612 citations

Strategies for multilocus linkage analysis in humans.

1984 • 2,600 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

A polymorphic DNA marker genetically linked to Huntington's disease

1983 • 2,329 citations

Analysis of Human Genetic Linkage.

1992 • 1,770 citations

Sex ratio and unisexual sterility in hybrid animals

1922 • 1,766 citations

Construction of Biologically Functional Bacterial Plasmids In Vitro

1973 • 1,699 citations

A General Model for the Genetic Analysis of Pedigree Data

1971 • 1,595 citations

Sequential tests for the detection of linkage.

1955 • 1,590 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

Easy calculations of lod scores and genetic risks on small computers.

1984 • 1,526 citations

Yeast transformation: a model system for the study of recombination.

1981 • 1,491 citations

A mechanism for gene conversion in fungi

1964 • 1,459 citations

Hyperlipidemia in Coronary Heart Disease II. GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA

1973 • 1,457 citations

The Genetics and Biology of Drosophila

1976 • 1,427 citations

Multilocus linkage analysis in humans: detection of linkage and estimation of recombination.

1985 • 1,207 citations

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

A mechanism for gene conversion in fungi

2007 • 1,149 citations

Recent advances in cytology

1932 • 1,087 citations

Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

1974 • 1,022 citations

Handbook of molecular cytology

1969 • 1,011 citations

Human Genetics. Problems and Approaches.

1980 • 1,010 citations

Human fetal gγ- and Aγ-globin genes: Complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes

1980 • 947 citations

Polymorphic DNA region adjacent to the 5' end of the human insulin gene.

1981 • 910 citations

DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory.

1983 • 895 citations

A general model for genetic recombination.

1975 • 890 citations

Classification of Hyperlipidaemias and Hyperlipoproteinaemias ,

1972 • 843 citations

Mutagenic deamination of cytosine residues in DNA

1980 • 761 citations

Hybridization of synthetic oligodeoxyribonucleotides to Φ_X174 DNA: the effect of single base pair mismatch

1979 • 753 citations

A highly polymorphic DNA marker linked to adult polycystic kidney disease on chromosome 16

1985 • 715 citations

The linear arrangement of six sex‐linked factors in Drosophila, as shown by their mode of association

1913 • 705 citations

Hyperlipidemia in Coronary Heart Disease I. LIPID LEVELS IN 500 SURVIVORS OF MYOCARDIAL INFARCTION

1973 • 630 citations

Logic of Statistical Inference.

1966 • 626 citations

Restriction sites containing CpG show a higher frequency of polymorphism in human DNA

1984 • 586 citations

THE SYNAPTONEMAL COMPLEX IN GENETIC SEGREGATION

1984 • 585 citations

Analysis of family resemblance. 3. Complex segregation of quantitative traits.

1974 • 569 citations

SOMATIC CROSSING OVER AND SEGREGATION IN DROSOPHILA MELANOGASTER

1936 • 540 citations

Detection of Single Base Substitutions by Ribonuclease Cleavage at Mismatches in RNA:DNA Duplexes

1985 • 538 citations

Localization of cystic fibrosis locus to human chromosome 7cen–q22

1985 • 498 citations

Cystic Fibrosis Locus Defined by a Genetically Linked Polymorphic DNA Marker

1985 • 488 citations

A unified model for complex segregation analysis.

1983 • 467 citations

A molecular map of the immune response region from the major histocompatibility complex of the mouse

1982 • 466 citations

A closely linked genetic marker for cystic fibrosis

1985 • 463 citations

Minor Xp21 chromosome deletion in a male associated with expression of Duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa, and McLeod syndrome.

1985 • 456 citations

Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion.

1985 • 455 citations

Restriction Endonucleases in the Analysis and Restructuring of DNA Molecules

1975 • 455 citations

Hyperlipidemia in Coronary Heart Disease

1973 • 449 citations

HOMOLOGOUS PAIRING AND STRAND EXCHANGE IN GENETIC RECOMBINATION

1982 • 443 citations

KINETICS OF THE GERMINAL EPITHELIUM IN MAN.

1964 • 438 citations

The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type.

1956 • 434 citations

Yeast recombination: the association between double-strand gap repair and crossing-over.

1983 • 432 citations

The Harvey Lectures . Delivered under the Auspices of The Harvey Society of New York, 1906-4, by Professors A. E. Wright, C. A. Herter, W. T. Porter, J. G. Adami, F. G. Benedict, E. B. Wilson, George S. Huntington, W. T. Councilman, Friedrioh Muller and Dr. S. J. Meltzer. Pp. 1414 Philadelphia and London, J. B. Lippincott Company. 1908.

1908 • 422 citations

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

1982 • 408 citations

Linkage analysis of two cloned DNA sequences flanking the Duchenne muscular dystrophy locus on the short arm of the human X chromosome

1983 • 394 citations

Complex Segregation Analysis with Pointers

1981 • 391 citations

The marker (X) syndrome: a cytogenetic and genetic analysis

1984 • 390 citations

Detection of deletions spanning the Duchenne muscular dystrophy locus using a tightly linked DNA segment

1985 • 390 citations

PRENATAL DIAGNOSIS AND CARRIER DETECTION OF DUCHENNE MUSCULAR DYSTROPHY WITH CLOSELY LINKED RFLPs

1985 • 380 citations

Detection of single base substitutions in total genomic DNA

1985 • 375 citations

Cloning of the breakpoint of an X;21 translocation associated with Duchenne muscular dystrophy

1985 • 368 citations

A strategy to reveal high-frequency RFLPs along the human X chromosome.

1984 • 361 citations

Extensions to Pedigree Analysis

1975 • 337 citations

Linkage relationship of a cloned DNA sequence on the short arm of the X chromosome to Duchenne muscular dystrophy

1982 • 334 citations

A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7

1985 • 332 citations

Report of the committee on methods of linkage analysis and reporting

1985 • 325 citations

Construction of linkage maps with DNA markers for human chromosomes

1985 • 325 citations

Analysis of human genetic linkage

1986 • 325 citations

Fragile sites on human chromosomes

1985 • 316 citations

Genetic tests under incomplete ascertainment.

1959 • 310 citations

A gradient of sex linkage in the pseudoautosomal region of the human sex chromosomes

1986 • 307 citations

RECENT ADVANCES IN CYTOLOGY

1937 • 303 citations

Testing for heterogeneity of recombination fraction values in Human Genetics

1963 • 303 citations

The human met oncogene is related to the tyrosine kinase oncogenes

1985 • 295 citations

Hypervariable telomeric sequences from the human sex chromosomes are pseudoautosomal

1985 • 295 citations

Chiasma distribution at diakinesis in the normal human male

2009 • 286 citations

Electron microscopy of meiosis in Drosophila melanogaster females

1975 • 281 citations

Genetic Recombination: Strand Transfer and Mismatch Repair

1978 • 270 citations

Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40.

1975 • 264 citations

The third-chromosome group of mutant characters of Drosophila melanogaster

1923 • 261 citations

The Mechanism Of Crossing-over...

2012 • 259 citations

Introduction to the mathematical theory of genetic linkage.

1961 • 253 citations

The meiotic system

1965 • 253 citations

Electron microscopy of meiosis in Drosophila melanogaster females: II: The recombination nodule—a recombination-associated structure at pachytene?

1975 • 252 citations

A Correlation of Cytological and Genetical Crossing-Over in Zea Mays

1931 • 249 citations

A Theory of Crossing-Over by Means of Hybrid Deoxyribonucleic Acid

1963 • 238 citations

Genetic recombination: The nature of a crossed strand-exchange between two homologous DNA molecules

1972 • 237 citations

Conjugation and Genetic Recombination in Escherichia coli K-12

1956 • 220 citations

The Genetic Linkage Map of the Human X Chromosome

1985 • 220 citations

Introduction to the Mathematical Theory of Genetic Linkage.

1962 • 219 citations

The genetics of Drosophila

1988 • 218 citations

Map Construction in Neurospora Crassa

1954 • 217 citations

Construction of human linkage maps: Likelihood calculations for multilocus linkage analysis

1986 • 215 citations

THE FINE STRUCTURE OF CHROMOSOMES IN THE MEIOTIC PROPHASE OF VERTEBRATE SPERMATOCYTES

1956 • 210 citations

MUTANTS AFFECTING MEIOSIS IN NATURAL POPULATIONS OF DROSOPHILA MELANOGASTER

1968 • 208 citations

Experimental studies in the physiology of heredity

1909 • 208 citations

Likelihood. An Account of the Statistical Concept of Likelihood and Its Application to Scientific Inference.

1973 • 204 citations

The telomeric region of the human X chromosome long arm: presence of a highly polymorphic DNA marker and analysis of recombination frequency.

1985 • 204 citations

REC-MEDIATED RECOMBINATIONAL HOT SPOT ACTIVITY IN BACTERIOPHAGE LAMBDA II. A MUTATION WHICH CAUSES HOT SPOT ACTIVITY

1974 • 201 citations

THE SIMULATION OF MENDELISM

1960 • 201 citations

Detection and sequence of mutations in the factor VIII gene of haemophiliacs

1985 • 198 citations

A NEW ESTIMATE OF THE LINKAGE BETWEEN THE GENES FOR COLOUR‐BLINDNESS AND HAEMOPHILIA IN MAN

1947 • 198 citations

Pseudoautosomal DNA sequences in the pairing region of the human sex chromosomes

1985 • 185 citations

Linkage analysis and family classification under heterogeneity

1983 • 177 citations

Molecular Mechanisms in Genetic Recombination

1982 • 176 citations

DNA restriction fragments associated with α1-antitrypsin indicate a single origin for deficiency allele PI Z

1985 • 171 citations

Mathematical Tables for Research Workers in Human Genetics.

1962 • 170 citations

Close linkage of fragile X-mental retardation syndrome to haemophilia B and transmission through a normal male

1983 • 169 citations

Recombination nodules and synaptonemal complex in recombination-defective females of Drosophila melanogaster

1979 • 167 citations

CROSSING‐OVER

1938 • 166 citations

Mismatch repair in heteroduplex DNA.

1975 • 165 citations

A Possible Influence of the Spindle Fibre on Crossing-Over in Drosophila

1932 • 159 citations

A genetic study of the temperate coliphage λ

1955 • 159 citations

The spatial relationship of the X and Y chromosomes during meiotic prophase in mouse spermatocytes

1970 • 158 citations

Denaturation and Renaturation of Deoxyribonucleic Acid12

1963 • 157 citations

International workshop on the fragile X and X‐linked mental retardation

1984 • 157 citations

HUMAN GENETICS

1984 • 155 citations

HUMAN APOLIPOPROTEIN MOLECULAR BIOLOGY AND GENETIC VARIATION

1985 • 155 citations

An attempt to analyze the constitution of the chromosomes on the basis of sex‐limited inheritance in Drosophila

1911 • 155 citations

Rec-mediated recombinational hot spot activity in bacteriophage lambda

1975 • 154 citations

Human meiosis II. Chromosome pairing and recombination nodules in human spermatocytes

1978 • 154 citations

Mechanics of meiosis

2009 • 152 citations

Quantification of the close association between DNA haplotypes and specific β-thalassaemia mutations in Mediterraneans

1984 • 149 citations

The information content of phase‐known matings for ordering genetic loci

1985 • 148 citations

SPECIAL SITES IN GENERALIZED RECOMBINATION

1979 • 147 citations

Analysis of DNA synthesis during meiotic prophase in Lilium

1971 • 144 citations

The linear arrangement of a series of alleles of Aspergillus nidulans

1955 • 144 citations

Muscular dystrophy in an X; 1 translocation female suggests that Duchenne locus is on X chromosome short arm.

1979 • 143 citations

PROGRESS IN MAPPING HUMAN AUTOSOMES

1969 • 141 citations

Genetic epidemiology of coronary heart disease. Past, present, and future.

1984 • 140 citations

Stocks for detecting linkage in the mouse, and the theory of their design

1951 • 138 citations

Statistical Inference

1949 • 136 citations

A mixed-model likelihood approximation on large pedigrees

1982 • 136 citations

Synthesis of DNA during meiosis.

1966 • 135 citations

A highly polymorphic locus in human DNA revealed by cosmid-derived probes.

1985 • 134 citations

Analysis of family resemblance. IV. Operational characteristics of segregation analysis.

1975 • 134 citations

Linkage relationships of paraoxonase (PON) with other markers: indication of PON‐cystic fibrosis synteny

1985 • 133 citations

MEIOTIC GENE CONVERSION IN YEAST TETRADS AND THE THEORY OF RECOMBINATION

1967 • 132 citations

The genetics of recombination

1977 • 132 citations

Recombinant DNA: A short course

1984 • 131 citations

Hyperlipidemia in Coronary Heart Disease III. EVALUATION OF LIPOPROTEIN PHENOTYPES OF 156 GENETICALLY DEFINED SURVIVORS OF MYOCARDIAL INFARCTION

1973 • 128 citations

Duchenne Muscular Dystrophy Involving Translocation of the dmd Gene Next to Ribosomal RNA Genes

1984 • 128 citations

Deletion of Huntington's disease-linked G8 (D4S10) locus in Wolf–Hirschhorn syndrome

1985 • 128 citations

STUDIES ON NUCLEI USING CORRELATED CYTOCHEMICAL, LIGHT, AND ELECTRON MICROSCOPE TECHNIQUES

1956 • 126 citations

STUDIES ON THE MECHANISM OF REVERSION IN BIOCHEMICAL MUTANTS OF NEUROSPORA CRASSA

1951 • 125 citations

INFORMATIONAL TRANSFER IN MEIOTIC GENE CONVERSION

1969 • 124 citations

The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity.

1983 • 124 citations

RECOMBINATION PATHWAY SPECIFICITY OF CHI

1977 • 123 citations

Gene conversion and polymorphism: Generation of mouse immunoglobulin γ2a chain alleles by differential gene conversion by γ2b chain gene

1983 • 119 citations

A linkage variation in Drosophila

1915 • 116 citations

Some comments on the statistical methods used in linkage investigations.

1959 • 113 citations

Efficiency and robustness of pedigree segregation analysis.

1978 • 112 citations

Marker (X)-Linked Mental Retardation

1983 • 111 citations

The Detection of Linkage in Human Genetics

1953 • 105 citations

The determination of position in crossing-over

1936 • 105 citations

A COMMON DNA POLYMORPHISM OF THE LOW-DENSITY LIPOPROTEIN (LDL) RECEPTOR GENE AND ITS USE IN DIAGNOSIS

1985 • 104 citations

Formation of hybrid DNA by rotary diffusion during genetic recombination

1972 • 103 citations

On the Molecular Basis of High Negative Interference

1974 • 103 citations

A Mapping Function for Man

1977 • 100 citations

Genetic Recombination: Understanding the Mechanisms

1982 • 99 citations

Meiosis in Aspergillus nidulans: Another example for lacking synaptonemal complexes in the absence of crossover interference

1982 • 98 citations

RECOMBINATION-DEFICIENT DELETIONS IN BACTERIOPHAGE Λ AND THEIR INTERACTION WITH CHI MUTATIONS

1975 • 97 citations

Genetic Recombination. Understanding the Mechanisms

1983 • 94 citations

Linkage map of the short arm of human chromosome 11: location of the genes for catalase, calcitonin, and insulin-like growth factor II.

1985 • 92 citations

THE ORIGIN AND BEHAVIOUR OF CHIASMATA

1932 • 92 citations

Chi, a promoter of generalized recombination in λ phage, is present in immunoglobulin genes

1981 • 90 citations

Fine and Coarse Controls of Genetic Recombination

1969 • 90 citations

The Theory of Genetical Recombination

1950 • 90 citations

Asynaptic meiosis in fission yeast?

2009 • 90 citations

Genetic analysis of idiopathic hemochromatosis using both qualitative (disease status) and quantitative (serum iron) information.

1985 • 89 citations

Confirmation of linkage of the loci for myotonic dystrophy and ABH secretion.

1971 • 88 citations

Sex differences in recombination of linked genes in animals

1967 • 88 citations

Extensions to Pedigree Analysis

1983 • 87 citations

A genetic analysis of therudimentarylocus ofDrosophila melanogaster

1971 • 86 citations

Regulation of Recombination at the His-3 Locus in Neurospora Crassa

1970 • 85 citations

Cytological mapping of the human glucose-6-phosphate dehydrogenase gene distal to the fragile-X site suggests a high rate of meiotic recombination across this site.

1984 • 84 citations

The use of computers

1982 • 83 citations

Analysis of exchanges in differentially stained meiotic chromosomes of Locusta migratoria after BrdU-substitution and FPG staining

1978 • 82 citations

On the lod score method in linkage analysis

1984 • 81 citations

Human meiosis VIII. Chromosome pairing and formation of the synaptonemal complex in oocytes

1983 • 80 citations

Complete Linkage in Drosophila melanogaster

1922 • 80 citations

Centromere localization at meiosis and the position of chiasmata in the male and female mouse

1972 • 76 citations

GENETICS OF SORDARIA FIMICOLA. V. ABERRANT SEGREGATION AT THE G LOCUS

1962 • 75 citations

A primary genetic map of chromosome 13q.

1986 • 75 citations

The Determination of Position in Crossing-over. II

1937 • 73 citations

Nuclear behavior during conjugation and meiosis in the fission yeast Schizosaccharomyces pombe.

1982 • 73 citations

Polymorphism and molecular pathology of the human beta-globin gene.

1983 • 73 citations

Beta-globin locus is linked to the parathyroid hormone (PTH) locus and lies between the insulin and PTH loci in man.

1983 • 72 citations

Recombination Mechanisms at the pan-2 Locus in Neurospora crassa

1958 • 71 citations

Genetic analysis of the fragile-X mental retardation syndrome with two flanking polymorphic DNA markers.

1986 • 70 citations

Molecular human cytogenetics

1977 • 69 citations

Recombination and amplification of pyrimidine‐rich sequences may be responsible for initiation and progression of the Xq27 fragile site: An hypothesis

1986 • 67 citations

Mutation and replication inUstilago maydis

1962 • 66 citations

GENETICS OF SORDARIA FIMICOLA. I. ASCOSPORE COLOR MUTANTS

1956 • 65 citations

Classifications and comparisons of multilocus recombination distributions

1978 • 65 citations

Genetic Mutations Affecting Human Lipoprotein Metabolism

1985 • 64 citations

The sex chromosome in the house mouse

1947 • 64 citations

Chiasma distribution in Truxaline grasshoppers

1967 • 62 citations

The behaviour of chromosomal axes during diplotene in mouse spermatocytes

1970 • 62 citations

Fine structure of chromosome pairing in ten Ascomycetes: meiotic and premeiotic (mitotic) synaptonemal complexes

1973 • 61 citations

The analysis of interference

1936 • 60 citations

An analysis of interference inAspergillus nidulans

1958 • 60 citations

Genetic linkage heterogeneity in the fragile X syndrome

1985 • 59 citations

Advances in human genetics. Vol. 1

1973 • 59 citations

Report of the committee on the genetic constitution of chromosomes 3 and 4

1985 • 58 citations

A preliminary linkage test with Agouti and Undulated mice

1949 • 58 citations

A BIOMETRICAL STUDY OF CROSSING OVER. ON THE MECHANISM OF CROSSING OVER IN THE THIRD CHROMOSOME OF DROSOPHILA MELANOGASTER

1919 • 58 citations

Variability of human linkage data.

1978 • 58 citations

Information Gain in Joint Linkage Analysis

1984 • 57 citations

Genetische Untersuchungen an einem heterothallischen Askomyzeten (Bombardia lunata nov. spec.)

1934 • 56 citations

Data for the study of sex‐linked inheritance in Drosophila

1912 • 56 citations

Interallelic recombination at the his-1 locus in Neurospora crassa and its genetic control

1965 • 55 citations

Homologous recombination promoted by Chi sites and RecBC enzyme of Escherichia coli

1985 • 53 citations

Linkage Analysis in Man

1980 • 52 citations

Male and female recombination fractions for the nail‐patella: ABO linkage in man

1965 • 51 citations

Site-specific cleavage of DNA at 8- and 10-base-pair sequences.

1984 • 51 citations

Biochemical analysis of meiosis in the male mouse

1977 • 51 citations

Chiasma frequency and distribution in a sample of human males: chromosomes 1, 2, and 9

1981 • 51 citations

A natural class of multilocus recombination processes and related measures of crossover interference

1979 • 50 citations

Analysis of crossing over in mouse meiotic cells by BrdU labelling technique

1980 • 50 citations

Bias of the estimated recombination fraction and lod score due to an association between a disease gene a marker gene

1982 • 50 citations

THE RELATIONSHIP OF GENE CONVERSION TO CROSSING OVER IN NEUROSPORA

1959 • 49 citations

Human meiosis IX. Crossing over and chiasma formation in oocytes

1985 • 49 citations

Aberrant 4:4 Asci, Disparity in the Direction of Conversion, and Frequencies of Conversion in Ascobolus immersus

1979 • 49 citations

Small nuclear RNA molecules that regulate nuclease accessibility in specific chromatin regions of meiotic cells

1981 • 49 citations

Construction of a map of the short arm of human chromosome 6.

1986 • 48 citations

A mapping function for human chromosomes

1976 • 48 citations

Gene conversion spectrum of 15 mutants giving post-meiotic segregation in the b2 locus of Ascobolus immersus

1978 • 48 citations

Regional mapping of six cloned DNA sequences on human chromosome 7.

1986 • 48 citations

ALLELIC RECOMBINATION IN NEUROSPORA: TETRAD ANALYSIS OF A THREE-POINT CROSS WITHIN THE pan-2 LOCUS

1964 • 48 citations

Genetically determined asynapsis, spermatogenic degeneration, and infertility in men.

1980 • 47 citations

Data and theory for a revised chiasma map of man

1982 • 47 citations

A maximum likelihood map of chromosome 1.

1979 • 45 citations

An analysis procedure illustrated on a triple linkage of use for prenatal diagnosis of myotonic dystrophy.

1971 • 44 citations

Correlated components of chiasma variation and the control of chiasma distribution in rye

1974 • 44 citations

Abuffspore colour mutant inSordaria brevicollisshowing high-frequency conversion

1979 • 44 citations

Linkage map of the mouse.

1986 • 44 citations

Localised chiasmata due to partial pairing: A 3D reconstruction of synaptonemal complexes in male Stethophyma grossum

1978 • 44 citations

Recombinant DNA: A short course

1984 • 43 citations

MUTABLE CHARACTERS OF DROSOPHILA VIRILIS I. REDDISH-ALPHA BODY CHARACTER

1928 • 42 citations

Meiosis in Mesostoma ehrenbergii ehrenbergii (Turbellaria, Rhabdocoela)

1982 • 41 citations

The Application of the Conception of Pure Lines to Sex-Limited Inheritance and to Sexual Dimorphism

1911 • 41 citations

Genetic controls of recombination I. The Recombination-2 gene of Neurospora crassa

1966 • 41 citations

Toward A General Theory of Genetic Recombination in Dna

1971 • 40 citations

Gene conversion: observations on the DNA hybrid models

1970 • 40 citations

The detection of major loci by segregation and linkage analysis: A simulation study

1984 • 40 citations

Intracellular pangenesis

1911 • 40 citations

A DNA probe for the LDL receptor gene is tightly linked to hypercholesterolemia in a pedigree with early coronary disease.

1986 • 39 citations

An alternative model of recombination and interference

1979 • 38 citations

Linkage mapping from pair-wise recombination data

1977 • 38 citations

Fragile sites on human chromosomes

1981 • 38 citations

THE SUPPRESSION OF GENE CONVERSION AND INTRAGENIC CROSSING OVER IN ASCOBOLUS IMMERSUS: EVIDENCE FOR MODIFIERS ACTING IN THE HETEROZYGOUS STATE

1974 • 37 citations

A MATHEMATICALLY TRACTABLE FAMILY OF GENETIC MAPPING FUNCTIONS WITH DIFFERENT AMOUNTS OF INTERFERENCE

1979 • 37 citations

Segregation of genetic markers in families with chromosome polymorphisms and structural rearrangements involving chromosome 1

1974 • 36 citations

Deletion mapping of HLA and chromosome 6p genes.

1985 • 35 citations

The theory of genetical recombination. I. Long-chromosome arms

1949 • 35 citations

The Mechanism of Crossing-Over. IV

1916 • 35 citations

A balanced three-point experiment for linkage group V of the house mouse

1957 • 34 citations

Meiotic crossing-over in lily and mouse

1977 • 34 citations

Genetic consequences of transfection with heteroduplex bacteriophage λ DNA

1975 • 34 citations

Genetic analysis of von Willebrand's disease in two large pedigrees: A multivariate approach

1980 • 34 citations

c-Ha-ras-1 oncogene lies between beta-globin and insulin loci on human chromosome 11p.

1984 • 33 citations

A Chiasma Map of Man

1977 • 33 citations

Effect on linkage maps of selection of crossovers between closely linked markers

1957 • 32 citations

The Relation of Parental Sex and Age to Recombination in the HL-A System

1973 • 32 citations

POLARIZED INTRAGENIC RECOMBINATION IN CHROMOSOME REARRANGEMENTS OF NEUROSPORA

1968 • 31 citations

Analysis of crossingover in man

1978 • 31 citations

Genetic linkage between a locus for 6-PGD and the Rh locus: evaluation of possible heterogeneity in the recombination fraction between sexes and among families.

1971 • 31 citations

Reddish—A Frequently “Mutating” Character in Drosophila Virilis

1926 • 31 citations

Linkage and recombination between fragile X-linked mental retardation and the factor IX gene

1985 • 31 citations

Complementation and recombination between Methionine-2 alleles in Neurospora crassa

1960 • 30 citations

Concerning the Stereochemistry of Strand Equivalence in Genetic Recombination

1974 • 30 citations

On the physical structure of λ recombinant DNA

1973 • 29 citations

Age trends in human chiasma frequencies and recombination fractions. I. Chiasma frequencies.

1975 • 29 citations

Repeated DNA synthesized during Pachytene in Lilium henryi

1973 • 28 citations

The frequency and distribution of chiasmata in man

1973 • 28 citations

Delta +-thalassemia in Sardinia

1983 • 28 citations

Intracellular pangenesis, including a paper on fertilization and hybridization,

1910 • 28 citations

Disparity of gene conversion in frameshift mutants located in locus b2 of Ascobolus immersus

1979 • 27 citations

Whole mount electron microscopy of metaphase

1972 • 25 citations

Crossing over between closely linked markers spanning the centromere of chromosome 3 inDrosophila melanogaster

1975 • 24 citations

DNA synthesized at pachytene in Lilium: A non-divergent subclass of moderately repetitive sequences

1980 • 24 citations

Optimizing selection of restriction enzyme in the search for ONA variants

1984 • 23 citations

Statistical Analysis of Multilocus Recombination

1983 • 23 citations

Recombination events that span sites within neighbouring gene loci ofNeurospora

1970 • 23 citations

Age trends in human chiasma frequencies and recombination fractions. II. Method for analyzing recombination fractions and applications to the ABO:nail-patella linkage.

1976 • 23 citations

Linkage data on Rh, PGM₁PGD, Peptidase C and Fy from family studies

1973 • 23 citations

Demonstration of a sex difference in recombination fraction in the loose linkage,RhandPGM₁

1972 • 22 citations

Crossing-over near the spindle fiber in attached-X chromosomes ofDrosophila melanogaster

1933 • 22 citations

Viability effects and recombination differences in a linkage test with pallid and fidget in the house mouse

1961 • 22 citations

Relationship between asymmetrical and symmetrical hybrid DNA formation during meiotic recombination

1980 • 21 citations

Conversion as a possible mechanism of high coincidence values in the centromere region of Drosophila

1975 • 21 citations

Forward and back mutation at specific loci in Neurospora.

1956 • 21 citations

Transreplication and Crossing Over in Sordaria fimicola

1961 • 21 citations

The organization of DNA segments undergoing repair synthesis during pachytene

1984 • 20 citations

Genetic recombination at the buff spore colour locus in Sordaria brevicollis

1979 • 19 citations

Sex Differences of Crossing-Over in Close Linkage

1953 • 17 citations

Evidence for non-random spatial distribution of meiotic exchanges in Podospora anserina: Comparison between linkage groups 1 and 6

1979 • 17 citations

The use of lod scores for the determination of the order of loci on a chromosome

1975 • 17 citations

A test of the role of two oncogenes in inherited predisposition to colon cancer.

1983 • 17 citations

Efficiency of lod scores for representing multiple locus linkage data

1985 • 16 citations

A hypothesis for the initiation of genetic recombination in eukaryotes

1982 • 16 citations

GENETIC HETEROZYGOSITY IN UNREPLICATED BACTERIOPHAGE Λ RECOMBINANTS

1975 • 16 citations

Über numerische Beziehungen der Crossover-Werte untereinander

1934 • 15 citations

Parental age and recombination frequency in the house mouse

1976 • 14 citations

The localization of eceriferum loci in barley

2009 • 14 citations

BIOLOGICAL SIGNIFICANCE OF COINCIDENCE IN CROSSING-OVER

1935 • 14 citations

A search for chromatid interference in the male house mouse

1954 • 13 citations

Unusual recombination values and the mapping of the lethal miniature in the house mouse

1972 • 13 citations

SEX AND CROSSING OVER IN TRIBOLIUM CASTANEUM

1964 • 13 citations

Population Differences in Meiotic Recombination Frequency between Loci on Chromosome 1

1974 • 12 citations

Looking for epilepsy genes

1984 • 11 citations

Correction of complex heteroduplexes made of mouse H-2 gene sequences in Escherichia coli K-12.

1984 • 10 citations

A Combinatorial Formulation of Multiple Linkage Tests

1951 • 10 citations

Linkage group I: a statistically significant locus order from family studies

1978 • 8 citations

[Heredity of diabetes mellitus].

1961 • 8 citations

The duplication and recombination of genes

1965 • 8 citations

Human Gene Mapping 8: Helsinki Conference (1985)

1986 • 6 citations

The mutation rate of the Rh-loci; a critical review.

1954 • 5 citations

Study of Meiosis in the Chimpanzee, <i>Pan troglodytes troglodytes</i> (Blumenbach 1779)

1972 • 3 citations

Characteristics of a linkage heterogeneity test

1978 • 3 citations

The Yale Human Gene Mapping Library

1984 • 2 citations

Fertilization and Hybridization

1909 • 2 citations

Deleted Work

1955 • 0 citations