On the lod score method in linkage analysis

Theoretical Statistics

1974 • 2,786 citations

Group sequential methods in the design and analysis of clinical trials

1977 • 1,679 citations

A General Model for the Genetic Analysis of Pedigree Data

1971 • 1,595 citations

Sequential tests for the detection of linkage.

1955 • 1,590 citations

Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

1974 • 1,022 citations

The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type.

1956 • 434 citations

Sequential Medical Trials.

1976 • 403 citations

Extensions to Pedigree Analysis

1975 • 337 citations

Interim Analyses for Randomized Clinical Trials: The Group Sequential Approach

1982 • 261 citations

Outline of Genetic Epidemiology.

1983 • 247 citations

Introduction to the Mathematical Theory of Genetic Linkage.

1962 • 219 citations

A NEW ESTIMATE OF THE LINKAGE BETWEEN THE GENES FOR COLOUR‐BLINDNESS AND HAEMOPHILIA IN MAN

1947 • 198 citations

Group Sequential Clinical Trials with Triangular Continuation Regions

1983 • 191 citations

Some comments on the statistical methods used in linkage investigations.

1959 • 113 citations

Further scoring types in sequential linkage tests, with a critical review of autosomal and partial sex linkage in man.

1957 • 93 citations

The use of computers

1982 • 83 citations

Methodology in Human Genetics

1963 • 82 citations

The prior probability of autosomal linkage

1975 • 81 citations

Size of cancer clinical trials and stopping rules

1978 • 78 citations

Statistical Aspects of Clinical Trial Design

1982 • 76 citations

Fixed-Sample-Size Analysis of Sequential Observations

1954 • 74 citations

Sequential Methods in Statistics.

1976 • 65 citations

Counting methods (EM algorithm) in human pedigree analysis: Linkage and segregation analysis

1977 • 63 citations

Variability of human linkage data.

1978 • 58 citations

Mathematical Tables for Research Workers in Human Genetics

1962 • 56 citations

A Source Book for Linkage in Man.

1979 • 53 citations

Linkage Analysis in Man

1980 • 52 citations

Repeated likelihood ratio tests

1979 • 42 citations

Sequential test for linkage between cystic fibrosis of the pancreas and the MNS locus.

1956 • 32 citations

Analysis of crossingover in man

1978 • 31 citations

Approximating the Normal Tail

1982 • 16 citations

The peak of the likelihood curve in linkage testing

1976 • 15 citations

Sequential Clinical Trials for Normal Variates Using Interval Composite Hypotheses

1981 • 15 citations

The interpretation of lods in linkage analysis

1976 • 13 citations

Cytogenetic surveillance of spontaneous abortions

1982 • 10 citations

Finite sample properties of maximum likelihood estimates of the recombination fraction in double backcross matings in man

1979 • 9 citations

On Sequenial Tests of the Bincknial Distribution

1970 • 7 citations

Statistical Inference

1955 • 6 citations

Some statistical properties of the lod method and the method of scoring known recombination events in linkage analysis

1978 • 4 citations

Rapid computer analysis of linkage data

1978 • 3 citations

On Sequenial Tests of the Binomial Distribution

1970 • 2 citations