The search for heterogeneity in insulin-dependent diabetes mellitus (IDDM): linkage studies, two-locus models, and genetic heterogeneity.

Sequential tests for the detection of linkage.

1955 • 1,590 citations

Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies.

1974 • 1,022 citations

HL-A, IMMUNE-RESPONSE GENES, AND DISEASE

1974 • 449 citations

The detection and estimation of linkage between the genes for elliptocytosis and the Rh blood type.

1956 • 434 citations

Testing for heterogeneity of recombination fraction values in Human Genetics

1963 • 303 citations

Insulin-Dependent Diabetes Mellitus: The Initial Lesion

1981 • 273 citations

Heterogeneity in Diabetes Mellitus—Update, 1978: Evidence for Further Genetic Heterogeneity within Juvenile-onset Insulin-dependent Diabetes Mellitus

1978 • 124 citations

Gene dosage and susceptibility to insulin‐dependent diabetes

1980 • 117 citations

X‐linkage and genetic heterogeneity in bipolar‐related major affective illness: reanalysis of linkage data

1982 • 109 citations

GENETIC MARKER FOR INSULIN-DEPENDENT DIABETES MELLITUS

1979 • 101 citations

A two locus model for juvenile diabetes

1980 • 97 citations

Studies of the HLA System and Insulin-dependent Diabetes Mellitus

1979 • 92 citations

A simple scheme for the analysis of HLA linkages in pedigrees

1978 • 82 citations

A three‐allele model for heterogeneity of juvenile onset insulin‐dependent diabetes

1980 • 71 citations

IgG Heavy-Chain (GM) Allotypes and Immune Response to Insulin in Insulin-Requiring Diabetes Mellitus

1981 • 69 citations

CLOSE GENETIC LINKAGE BETWEEN DIABETES MELLITUS AND KIDD BLOOD GROUP

1981 • 67 citations

The modes of inheritance of insulin-dependent diabetes mellitus or the genetics of IDDM, no longer a nightmare but still a headache.

1981 • 66 citations

Counting methods (EM algorithm) in human pedigree analysis: Linkage and segregation analysis

1977 • 63 citations

Variability of human linkage data.

1978 • 58 citations

Some epistatic two-locus models of disease. II. The confounding of linkage and association.

1981 • 55 citations

Bias of the estimated recombination fraction and lod score due to an association between a disease gene a marker gene

1982 • 50 citations

The 1981 catalogue of assigned human genetic markers and report of the nomenclature committee

1982 • 45 citations

Genetic Susceptibility to Diabetes Mellitus: the Distribution of Properdin Factor B (Bf) and Glyoxalase (GLO) Phenotypes

1979 • 42 citations

Genetics of Type I diabetes mellitus: a single, recessive predisposition gene mapping between HLA-B and GLO. With an appendix on the estimation of selection bias.

1981 • 39 citations

BF types and the mode of inheritance of insulin-dependent diabetes mellitus (IDDM)

1981 • 38 citations

Genetic studies of insulin‐dependent diabetes mellitus: segregation and linkage analyses

1982 • 35 citations

A simple method for testing two-locus models of inheritance.

1981 • 33 citations

A search for heterogeneity in insulin dependent diabetes mellitus (IDDM): HLA and autoimmune studies in simplex, multiplex and multigenerational families

1983 • 30 citations

Juvenile insulin‐dependent diabetes: a possible susceptibility gene in interaction with HLA

1981 • 29 citations

Heterogeneity of insulin‐dependent diabetes–new evidence

1982 • 24 citations

No Evidence for Linkage Between Diabetes and the Kidd Marker

1982 • 21 citations

The increased frequency of the Lewis negative blood group in a diabetic population

1978 • 21 citations

Report of the committee on the genetic constitution of chromosome 1

1982 • 17 citations

LINKAGE DISEQUILIBRIUM BETWEEN INSULIN-DEPENDENT DIABETES AND THE KIDD BLOOD GROUP Jk^bALLELE

1982 • 15 citations

Current concepts of diabetic complications with emphasis on hereditary factors: a brief review.

1979 • 14 citations

Genetic Polymorphisms in Juvenile-Onset Diabetes

1978 • 10 citations

The search for heterogeneity in insulin‐dependent diabetes mellitus: Evidence for familial and nonfamilial forms

1983 • 9 citations

Analysis of linkage relationships of Co, Jk and K with each other and with chromosome 2 loci ACP1 and Km

1982 • 7 citations

The HLAB* 18,BF* F1 in haplotype in type 1 diabetes

1982 • 3 citations