Identification of molecular contacts between the U1 A small nuclear ribonucleoprotein and U1 RNA.

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

1987 • 2,098 citations

Structure of yeast phenylalanine tRNA at 3 Å resolution

1974 • 1,000 citations

Three-Dimensional Tertiary Structure of Yeast Phenylalanine Transfer RNA

1974 • 970 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Structure of E. coli Glutaminyl-tRNA Synthetase Complexed with tRNA ^Gln and ATP at 2.8 Å Resolution

1989 • 888 citations

Probing the structure of RNAs in solution

1987 • 721 citations

RNA-binding proteins as developmental regulators.

1989 • 679 citations

Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A

1990 • 622 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing

1987 • 594 citations

Recognition of a DNA Operator by the Repressor of Phage 434: A View at High Resolution

1988 • 531 citations

Structural studies of protein–nucleic acid interaction: the sources of sequence-specific binding

1990 • 508 citations

Structure of the Lambda Complex at 2.5 Å Resolution: Details of the Repressor-Operator Interactions

1988 • 500 citations

Structure of spliceosomal snRNPs and their role in pre-mRNA splicing

1990 • 407 citations

Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

1988 • 401 citations

A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability.

1987 • 401 citations

Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.

1989 • 314 citations

Crystal structure of yeast tRNAAsp

1980 • 291 citations

Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B" and their cognate RNAs

1990 • 283 citations

Primary structure of human nuclear ribonucleoprotein particle C proteins: conservation of sequence and domain structures in heterogeneous nuclear RNA, mRNA, and pre-rRNA-binding proteins.

1987 • 229 citations

cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins.

1987 • 203 citations

[16] Enzymatic approaches to probing of RNA secondary and tertiary structure

1989 • 192 citations

Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein.

1988 • 180 citations

A Proposed Model for Interaction of Polypeptides with RNA

1974 • 165 citations

A Single Domain of Yeast Poly(A)-Binding Protein Is Necessary and Sufficient for RNA Binding and Cell Viability

1987 • 158 citations

In vitro assembly of U1 snRNPs.

1987 • 145 citations

Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA.

1990 • 139 citations

Mapping tRNA structure in solution using double-strand-specific ribonuclease V₁from cobra venom

1981 • 131 citations

Yeast tRNAAsp tertiary structure in solution and areas of interaction of the tRNA with aspartyl-tRNA synthetase

1985 • 128 citations

Secondary structural complementarity between DNA and proteins.

1977 • 111 citations

Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B" antigen.

1987 • 108 citations

Primary Structure of Human Nuclear Ribonucleoprotein Particle C Proteins: Conservation of Sequence and Domain Structures in Heterogeneous Nuclear RNA, mRNA, and Pre-rRNA-Binding Proteins

1987 • 94 citations

The U2B″ RNP motif as a site of protein-protein interaction.

1990 • 93 citations

Rapid RNA sequencing: nucleases from Staphylococcus aureus and Neurospora crassa discriminate between uridine and cytidine

1979 • 84 citations

The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins.

1988 • 75 citations

Solution structure of human U1 snRNA. Derivation of a possible three-dimensional model

1990 • 68 citations

Cloning and expression of the bacteriophage T3 RNA polymerase gene

1986 • 68 citations

Multiple domains of U1 snRNA, including U1 specific protein binding sites, are required for splicing.

1990 • 59 citations

Structure-probing of U1 snRNPs gradually depleted of the U1-specific proteins A, C and 70k. Evidence that A interacts differentially with developmentally regulated mouse U1 snRNA variants

1990 • 55 citations

Splicing stories and poly(A) tales: an update on RNA processing and transport

1990 • 53 citations