Structure-probing of U1 snRNPs gradually depleted of the U1-specific proteins A, C and 70k. Evidence that A interacts differentially with developmentally regulated mouse U1 snRNA variants

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation

1986 • 755 citations

RNA-binding proteins as developmental regulators.

1989 • 679 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing

1987 • 594 citations

The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro

1983 • 593 citations

Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

1988 • 401 citations

Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA

1986 • 389 citations

Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding

1986 • 386 citations

A human autoimmune protein associated with U1 RNA contains a region of homology that is cross-reactive with retroviral p30gag antigen

1987 • 312 citations

Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

1985 • 307 citations

Isolation of small nuclear ribonucleoproteins containing U1, U2, U4, U5, and U6 RNAs.

1983 • 245 citations

U2 RNA shares a structural domain with U1, U4, and U5 RNAs.

1982 • 236 citations

Cloning of the human cDNA for the U1 RNA-associated 70K protein.

1986 • 235 citations

cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins.

1987 • 203 citations

Structural organization of ribonucleoproteins containing small nuclear RNAs from HeLa cells

1982 • 184 citations

Purification of the individual snRNPs U1, U2, U5 and U4/U6 from HeLa cells and characterization of their protein constituents.

1986 • 170 citations

A binding consensus: RNA-protein interactions in splicing, snRNPs, and sex

1989 • 162 citations

20S small nuclear ribonucleoprotein U5 shows a surprisingly complex protein composition.

1989 • 148 citations

The human U1-70K snRNP protein: cDNA cloning, chromosomal localization, expression, alternative splicing and RNA-binding

1987 • 148 citations

In vitro assembly of U1 snRNPs.

1987 • 145 citations

Purification of snRNPs U1, U2, U4, U5 and U6 with 2,2,7-trimethylguanosine-specific antibody and definition of their constituent proteins reacting with anti-Sm and anti-(U1)RNP antisera.

1983 • 143 citations

A monoclonal antibody against 2,2,7‐trimethylguanosine that reacts with intact, class U, small nuclear ribonucleoproteins as well as with 7‐methylguanosine‐capped RNAs

1987 • 133 citations

Fractionation and characterization of human small nuclear ribonucleoproteins containing U1 and U2 RNAs.

1983 • 126 citations

Differential Control of U1 Small Nuclear RNA Expression During Mouse Development

1985 • 112 citations

Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B" antigen.

1987 • 108 citations

Subnuclear particles containing a small nuclear RNA and heterogeneous nuclear RNA

1981 • 96 citations

Distribution of the 70K U1 RNA-associated protein during interphase and mitosis: correlation with other U RNP particles and proteins of the nuclear matrix

1986 • 94 citations

Human Ul snRNP-specificC protein: complete cDNA and protein sequence and identification of a multigene family in mammals

1988 • 90 citations

Direct, sequence-specific binding of the human U1-70K ribonucleoprotein antigen protein to loop I of U1 small nuclear RNA.

1989 • 89 citations

Characterization of U small nuclear RNA-associated proteins.

1984 • 83 citations

The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins.

1988 • 75 citations

The U1 RNA-Binding Site of the U1 Small Nuclear Ribonucleoprotein (snRNP)-Associated A Protein Suggests a Similarity with U2 snRNPs

1989 • 58 citations

Loop I of U1 Small Nuclear RNA Is The Only Essential RNA Sequence for Binding of Specific U1 Small Nuclear Ribonucleoprotein Particle Proteins

1988 • 54 citations

Direct, Sequence-Specific Binding of the Human U1-70K Ribonucleoprotein Antigen Protein to Loop I of U1 Small Nuclear RNA

1989 • 44 citations

U1 small nuclear ribonucleoprotein particle-specific proteins interact with the first and second stem-loops of U1 RNA, with the A protein binding directly to the RNA independently of the 70K and Sm proteins.

1989 • 43 citations

Isolation of a pure U1 snRNP from HeLa cells

1982 • 27 citations

U1 Small Nuclear Ribonucleoprotein Particle-Specific Proteins Interact with the First and Second Stem-Loops of Ul RNA, with the A Protein Binding Directly to the RNA Independently of the 70K and Sm Proteins

1989 • 22 citations