Enteroviral Myocarditis and Dilated Cardiomyopathy: a Review of Clinical and Experimental Studies

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1992 • 2,725 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide

1992 • 1,635 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Structure of a human common cold virus and functional relationship to other picornaviruses

1985 • 1,419 citations

The Molecular Cell Biology of Interferon-gamma and its Receptor

1993 • 1,323 citations

CYTOKINES: COORDINATORS OF IMMUNE AND INFLAMMATORY RESPONSES

1990 • 1,304 citations

Myocarditis. A histopathologic definition and classification.

1987 • 1,282 citations

Three-Dimensional Structure of Poliovirus at 2.9 Å Resolution

1985 • 1,253 citations

The major human rhinovirus receptor is ICAM-1

1989 • 1,134 citations

Cellular receptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily

1989 • 1,086 citations

Profound block in thymocyte development in mice lacking p56lck

1992 • 965 citations

The natural history of idiopathic dilated cardiomyopathy

1981 • 957 citations

Management of patients with intramural hematoma of the thoracic aorta.

1993 • 896 citations

Requirement for Transcription Factor IRF-1 in NO Synthase Induction in Macrophages

1994 • 840 citations

A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses

1989 • 825 citations

Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase

1993 • 825 citations

Viral myocarditis. A review.

1980 • 810 citations

Myocarditis: The Dallas criteria

1987 • 767 citations

Nitric oxide, a novel biologic messenger

1992 • 754 citations

Report of the WHO/ISFC task force on the definition and classification of cardiomyopathies.

1980 • 731 citations

Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart.

1993 • 708 citations

Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.

1993 • 656 citations

Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development

1993 • 638 citations

Induction and potential biological relevance of a Ca²⁺‐independent nitric oxide synthase in the myocardium

1992 • 623 citations

Epidemiology of idiopathic dilated and hypertrophic cardiomyopathy. A population-based study in Olmsted County, Minnesota, 1975-1984.

1989 • 621 citations

DETECTION OF COXSACKIE-B-VIRUS-SPECIFIC RNA SEQUENCES IN MYOCARDIAL BIOPSY SAMPLES FROM PATIENTS WITH MYOCARDITIS AND DILATED CARDIOMYOPATHY

1986 • 605 citations

A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA

1985 • 550 citations

A glycolipid on the surface of mouse natural killer cells

1980 • 539 citations

Cardiac myosin induces myocarditis in genetically predisposed mice.

1987 • 507 citations

Interleukin 1 and tumor necrosis factor inhibit cardiac myocyte beta-adrenergic responsiveness.

1989 • 493 citations

Ongoing enterovirus-induced myocarditis is associated with persistent heart muscle infection: quantitative analysis of virus replication, tissue damage, and inflammation.

1992 • 458 citations

Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium.

1993 • 457 citations

Long-term beta-blockade in dilated cardiomyopathy. Effects of short- and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol.

1989 • 447 citations

Viral and Rickettsial Infections of Man.

1966 • 438 citations

Evaluation of Postmortem Endomyocardial Biopsy Specimens From 38 Patients With Lymphocytic Myocarditis: Implications for Role of Sampling Error

1989 • 427 citations

EPR characterization of molecular targets for NO in mammalian cells and organelles

1993 • 373 citations

Nitric oxide synthase activities in human myocardium

1993 • 358 citations

Roles of alphabeta and gammadelta T Cell Subsets in Viral Immunity

1992 • 350 citations

Insensitivity of right ventricular endomyocardial biopsy in the diagnosis of myocarditis

1989 • 344 citations

General primer-mediated polymerase chain reaction for detection of enteroviruses: application for diagnostic routine and persistent infections

1992 • 342 citations

Clinicopathoiogic description of myocarditis

1991 • 337 citations

Myosin-induced acute myocarditis is a T cell-mediated disease.

1991 • 332 citations

Detection of enterovirus RNA in myocardial biopsies from patients with myocarditis and cardiomyopathy using gene amplification by polymerase chain reaction.

1990 • 316 citations

In situ detection of enteroviral genomes in myocardial cells by nucleic acid hybridization: an approach to the diagnosis of viral heart disease.

1987 • 313 citations

Identification of the Integrin VLA-2 as a Receptor for Echovirus 1

1992 • 310 citations

Involvement of T Lymphocytes in the Pathogenesis of Coxsackie Virus B3 Heart Disease

1974 • 310 citations

The Registry of the International Society for Heart Transplantation: seventh official report--1990.

1990 • 305 citations

Peripartum Cardiomyopathy

1971 • 304 citations

Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus: clearance of virus in vivo

1984 • 296 citations

Enteroviruses in human disease.

1978 • 296 citations

Microvascular spasm in the cardiomyopathic Syrian hamster: a preventable cause of focal myocardial necrosis.

1982 • 295 citations

Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome.

1986 • 275 citations

Endomyocardial Biopsy

1962 • 273 citations

Peripartum myocarditis and cardiomyopathy.

1990 • 269 citations

Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy.

1990 • 260 citations

Complete nucleotide sequence of infectious Coxsackievirus B3 cDNA: two initial 5' uridine residues are regained during plus-strand RNA synthesis

1990 • 254 citations

cDNA cloning reveals that the major group rhinovirus receptor on HeLa cells is intercellular adhesion molecule 1.

1989 • 251 citations

Antibodies to Coxsackie B viruses in congestive cardiomyopathy.

1979 • 244 citations

Coxsackievirus B-3 myocarditis in Balb/c mice. Evidence for autoimmunity to myocyte antigens.

1984 • 243 citations

Molecular mimicry: frequency of reactivity of monoclonal antiviral antibodies with normal tissues

1986 • 243 citations

Functional analysis of T lymphocyte subsets in antiviral host defense.

1987 • 237 citations

Group B Coxsackievirus Infections in Infants Younger than Three Months of Age: A Serious Childhood Illness

1983 • 234 citations

Peripartum cardiomyopathy: Clinical, hemodynamic, histologic and prognostic characteristics

1986 • 233 citations

The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids

1992 • 233 citations

Gamma Interferon Synthesis by Human Thymocytes and T Lymphocytes Inhibited by Cyclosporin A

1983 • 225 citations

Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to Coxsackievirus B3-induced myocarditis.

1987 • 224 citations

Viral infection and the pathogenesis of dilated cardiomyopathy.

1994 • 224 citations

Coxsackie B myopericarditis in adults

1970 • 220 citations

Myocarditis

1947 • 218 citations

Immunological analysis of auto-antibodies against the adenine nucleotide translocator in dilated cardiomyopathy

1985 • 214 citations

Peripartum Cardiomyopathy Due to Myocarditis

1982 • 209 citations

Receptor affinities as major determinants of enterovirus tissue tropisms in humans

1961 • 208 citations

Interleukin 1 or tumor necrosis factor can promote Coxsackie B3-induced myocarditis in resistant B10.A mice.

1992 • 207 citations

T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses

1988 • 205 citations

Variations in the susceptibility to Coxsackievirus B3-induced myocarditis among different strains of mice.

1986 • 203 citations

Peripartum Cardiomyopathy

1985 • 203 citations

Novel organ-specific circulating cardiac autoantibodies in dilated cardiomyopathy

1990 • 200 citations

Genome of coxsackievirus B3

1987 • 196 citations

An animal model of congestive (dilated) cardiomyopathy: dilatation and hypertrophy of the heart in the chronic stage in DBA/2 mice with myocarditis caused by encephalomyocarditis virus.

1982 • 194 citations

Indium 111-monoclonal antimyosin antibody imaging in the diagnosis of acute myocarditis.

1987 • 189 citations

ADULT HEART DISEASE DUE TO THE COXSACKIE VIRUS B INFECTION

1968 • 188 citations

Enteroviral infection of mice with severe combined immunodeficiency. Evidence for direct viral pathogenesis of myocardial injury.

1992 • 186 citations

Antimyosin antibody cardiac imaging: Its role in the diagnois of myocarditis

1990 • 184 citations

A monoclonal antibody specific for the cellular receptor for the group B coxsackieviruses

1988 • 182 citations

AUGMENTATION OF THE VIRULENCE OF MURINE COXSACKIE-VIRUS B-3 MYOCARDIOPATHY BY EXERCISE

1970 • 178 citations

Cytotoxic and viral neutralizing antibodies crossreact with streptococcal M protein, enteroviruses, and human cardiac myosin.

1992 • 178 citations

Defective in vitro suppressor cell function in idiopathic congestive cardiomyopathy.

1979 • 178 citations

Diagnostic relevance of humoral and cell-mediated immune reactions in patients with acute viral myocarditis.

1982 • 175 citations

H-2 compatibility requirement for virus-specific T cell-mediated effector functions in vivo. I. Specificity of T cells conferring antiviral protection against lymphocytic choriomeningitis virus is associated with H-2K and H-2D.

1976 • 173 citations

Direct Myocardial Injury by Enterovirus: A Central Role in the Evolution of Murine Myocarditis

1993 • 172 citations

New Aspects of Positive-Strand Rna Viruses

1990 • 170 citations

Unrelated animal viruses share receptors

1976 • 167 citations

Coxsackie B viral myocarditis and valvulitis identified in routine autopsy specimens by immunofluorescent techniques

1967 • 162 citations

Viral myocarditis: A paradigm for understanding the pathogenesis and treatment of dilated cardiomyopathy

1993 • 162 citations

Peripartum cardiomyopathies: A review

1984 • 159 citations

HLA class II (DR and DQ) antigen associations in idiopathic dilated cardiomyopathy. Validation study and meta-analysis of published HLA association studies.

1991 • 159 citations

Gallium-67 imaging in patients with dilated cardiomyopathy and biopsy-proven myocarditis.

1984 • 155 citations

Residual pathologic changes following murine coxsackie A and B myocarditis.

1969 • 153 citations

Heart-specific autoantibodies following murine coxsackievirus B3 myocarditis.

1985 • 148 citations

Reduced suppressor cell activity in congestive cardiomyopathy and in myocarditis.

1982 • 145 citations

Infectious Diseases of the Fetus and Newborn Infant

1990 • 143 citations

End-stage dilated cardiomyopathy. Persistence of enterovirus RNA in myocardium at cardiac transplantation and lack of immune response.

1989 • 143 citations

THE INDUCTION OF GROSS MYOCARDIAL LESIONS BY A COXSACKIE (PLEURODYNIA) VIRUS AND CORTISONE 12

1956 • 141 citations

DEFICIENT NATURAL KILLER CELL ACTIVITY IN PATIENTS WITH IDIOPATHIC DILATED CARDIOMYOPATHY

1982 • 140 citations

Role of IL-1 and tumor necrosis factor in coxsackie virus-induced autoimmune myocarditis.

1993 • 138 citations

Coxsackievirus B-3 myocarditis. Identification of different pathogenic mechanisms in DBA/2 and Balb/c mice.

1986 • 138 citations

Usefulness of magnetic resonance imaging for diagnosis of acute myocarditis in infants and children, and comparison with endomyocardial biopsy

1991 • 136 citations

Antibodies to the ADP/ATP carrier, an autoantigen in myocarditis and dilated cardiomyopathy, penetrate into myocardial cells and disturb energy metabolism in vivo.

1989 • 135 citations

A search for the presence of the enteroviral capsid protein VP1 in pancreases of patients with Type 1 (insulin-dependent) diabetes and pancreases and hearts of infants who died of coxsackieviral myocarditis

1990 • 134 citations

Constitutive expression of an ISGF2/IRF1 transgene leads to interferon-independent activation of interferon-inducible genes and resistance to virus infection

1992 • 133 citations

Autoantibodies against the -adrenergic receptor in human myocarditis and dilated cardiomyopathy: -adrenergic agonism without desensitization

1991 • 133 citations

Coxsackie B3 virus can replicate in cultured human foetal heart cells and is inhibited by interferon

1985 • 133 citations

Laminin distribution and autoantibodies to laminin in dilated cardiomyopathy and myocarditis

1989 • 130 citations

Effects of prednisolone on acute viral myocarditis in mice

1986 • 130 citations

Indium-111 antimyosin scintigraphy to assess myocardial damage in patients with suspected myocarditis and cardiac rejection.

1988 • 129 citations

Establishment of cell lines persistently infected with foot-and-mouth disease virus

1985 • 126 citations

Murine natural killer cells limit coxsackievirus B3 replication.

1987 • 126 citations

CHRONIC RELAPSING PERICARDITIS AND DILATED CARDIOMYOPATHY: SEROLOGICAL EVIDENCE OF PERSISTENT ENTEROVIRUS INFECTION

1989 • 124 citations

Idiopathic Cardiomyopathy A Study on the Infectious-Immune Theory as a Cause of the Disease

1971 • 123 citations

Involvement of natural killer cells in coxsackievirus B3-induced murine myocarditis.

1986 • 121 citations

A six-year study of coxsackievirus B infections in heart disease

1974 • 121 citations

Coxsackievirus B-3 myocarditis. Acute and chronic forms of the disease caused by different immunopathogenic mechanisms.

1987 • 120 citations

Viral heart disease

1989 • 118 citations

The registry of the International Society for heart transplantation: Sixth official report—1989

1990 • 118 citations

Detection of Coxsackievirus B3 RNA in myocardial tissues by the polymerase chain reaction.

1991 • 117 citations

Vitamin E Deficiency Intensifies the Myocardial Injury of Coxsackievirus B3 Infection of Mice

1994 • 116 citations

The Influence of Quantitated Post-Weaning Undernutrition on Coxsackievirus B3 Infection of Adult Mice. I. Viral Persistence and Increased Severity of Lesions

1970 • 115 citations

A nonsteroid anti-inflammatory drug exacerbates coxsackie B3 murine myocarditis

1985 • 115 citations

Lysis of infected myofibers by coxsackievirus B-3-immune T lymphocytes.

1980 • 114 citations

Classification and natural history of primary myocardial disease

1984 • 114 citations

High frequency of antigenic variants among naturally occurring human Coxsackie B4 virus isolates identified by monoclonal antibodies

1982 • 114 citations

Myocarditis and cardiomyopathy after arbovirus infections (dengue and chikungunya fever).

1972 • 112 citations

The Role of Antibody and Host Cells in the Resistance of Mice Against Infection by Coxsackie B-3 Virus

1973 • 111 citations

Differential effects of myocarditic variants of Coxsackievirus B3 in inbred mice. A pathologic characterization of heart tissue damage.

1991 • 111 citations

Search for Coxsackievirus B3 RNA in idiopathic dilated cardiomyopathy using gene amplification by polymerase chain reaction

1992 • 109 citations

Cardiac Manifestations During a Coxsackie B5 Epidemic

1968 • 108 citations

COXSACKIE-B-VIRUS-SPECIFIC IgM RESPONSES IN PATIENTS WITH CARDIAC AND OTHER DISEASES

1980 • 108 citations

Therapy with cyclosporine in experimental murine myocarditis with encephalomyocarditis virus.

1986 • 107 citations

Altered receptor specificity of coxsackievirus B3 after growth in rhabdomyosarcoma cells

1984 • 107 citations

A molecular and serologic evaluation of enteroviral involvement in human myocarditis

1990 • 106 citations

Lymphokine dependence of in vivo expression of MHC class II antigens by endothelium

1985 • 106 citations

Generation of cytotoxic T lymphocytes during coxsackievirus tb-3 infection. II. Characterization of effector cells and demonstration cytotoxicity against viral-infected myofibers1.

1977 • 106 citations

Exercise in coxsackie B3 myocarditis: Effects on heart lymphocyte subpopulations and the inflammatory reaction

1989 • 104 citations

Coxsackievirus induced myocarditis in mice: cardiac myosin autoantibodies do not cross-react with the virus.

1987 • 103 citations

Cardiac myosin-induced myocarditis. Heart autoantibodies are not involved in the induction of the disease.

1990 • 103 citations

Etiology of Mild Acute Infectious Myocarditis

1983 • 103 citations

Interleukin-1-induced myocardial depression in an isolated beating heart preparation.

1989 • 102 citations

Effect of rabbit anti-asialo GM1 treatment in vivo or with anti-asialo GM1 plus complement in vitro on cytotoxic T cell activities.

1986 • 102 citations

Treatment of viral myocarditis with ribavirin in an animal preparation.

1985 • 101 citations

Augmentation of pathogenesis of coxsackievirus B3 infections in mice by exogenous administration of interleukin-1 and interleukin-2

1994 • 101 citations

Peripartum heart disease: an endomyocardial biopsy study.

1986 • 100 citations

Lethal Infection with Coxsackie Virus of Adult Mice Given Cortisone

1951 • 99 citations

H-2 Compatibility Requirement for Virus-Specific T Cell-Mediated Effector Functions in Vivo

1976 • 99 citations

A subset of mouse monoclonal antibodies cross-reactive with cytoskeletal proteins and group A streptococcal M proteins recognizes N-acetyl-beta-D-glucosamine.

1993 • 98 citations

Cardiac injury in myocarditis induced by coxsackievirus group B, type 3 in Balb/c mice is mediated by Lyt 2+ cytolytic lymphocytes

1984 • 98 citations

An in vivo validation of quantitative blood flow imaging in arteries and veins using magnetic resonance phase-shift techniques

1991 • 97 citations

Generation of cytotoxic T lymphocytes during coxsackievirus B-3 infection. I. Model and viral specificity1.

1977 • 96 citations

Clinical and experimental aspects of viral myocarditis

1989 • 96 citations

Detection of enteroviral RNA in idiopathic dilated cardiomyopathy and other human cardiac tissues.

1992 • 95 citations

Serious Coxsackie Infection in Infants and Children

1958 • 95 citations

Purification of a HeLa cell receptor protein for group B coxsackieviruses

1985 • 94 citations

Viral Myocarditis Leading to Cardiomyopathy: Do Cytokines Contribute to Pathogenesis?

1993 • 93 citations

Molecular probes for detection of persisting enterovirus infection of human heart and their prognostic value

1991 • 93 citations

Incidence of myocarditis. A 10-year autopsy study from Malmö, Sweden.

1991 • 92 citations

Effects of Immunosuppression on Coxsackie B-3 Virus Infection in Mice, and Passive Protection by Circulating Antibody

1973 • 89 citations

Beta-adrenoceptor antibodies and genetics in dilated cardiomyopathy-- An overview and review

1991 • 89 citations

Influence of sex hormones on Coxsackie B-3 virus infection in Balb/c mice

1982 • 88 citations

Long-term follow-up of acute myocarditis. Correlation of ventricular function and outcome

1987 • 88 citations

Verapamil ameliorates the clinical and pathological course of murine myocarditis.

1992 • 88 citations

Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines

1985 • 87 citations

Comparison of clinical findings in idiopathic dilated cardiomyopathy in women versus men

1993 • 87 citations

Coxsackievirus B3-induced production of tumor necrosis factor-alpha, IL-1 beta, and IL-6 in human monocytes.

1992 • 86 citations

The Detection of Coxsackievirus RNA in Cardiac Tissue by in situ Hybridization

1988 • 84 citations

HLA A, B and DR typing in idiopathic dilated cardiomyopathy: A search for immune response factors

1984 • 84 citations

Beneficial effects of captopril in acute coxsackievirus B3 murine myocarditis.

1990 • 83 citations

Anti-beta-receptor antibodies in human dilated cardiomyopathy and correlation with HLA-DR antigens

1990 • 83 citations

Routine use of μ‐antibody‐capture elisa for the serological diagnosis of coxsackie b virus infections

1986 • 83 citations

Effect of metoprolol in acute coxsackievirus B3 murine myocarditis

1988 • 82 citations

COXSACKIE VIRUS B3 MYOCARDITIS IN MICE. AN ELECTRON MICROSCOPIC, IMMUNOFLUORESCENT AND VIRUS-ASSAY STUDY.

1964 • 82 citations

Heart disease caused by Coxsackie virus B infection.

1975 • 80 citations

Cardiac persistence of cardioviral RNA detected by polymerase chain reaction in a murine model of dilated cardiomyopathy.

1992 • 78 citations

Virus and the Heart

1971 • 78 citations

Incidence of congestive cardiomyopathy

1978 • 78 citations

Cardiomyopathy in western Denmark.

1984 • 77 citations

Immunochemical characterization of the adenine nucleotide translocator

1984 • 77 citations

Strand-specific detection of enteroviral RNA in myocardial tissue by in situ hybridization

1991 • 76 citations

The Role of Antibodies in Natural and Acquired Resistance of Mice to Vesicular Stomatitis Virus

1988 • 75 citations

Similar prevalence of enteroviral genome within the myocardium from patients with idiopathic dilated cardiomyopathy and controls by the polymerase chain reaction

1992 • 75 citations

Secondary enterovirus infection in the murine model of myocarditis. Pathologic and immunologic aspects.

1990 • 73 citations

Coxsackievirus B3 from an infectious cDNA copy of the genome is cardiovirulent in mice

1992 • 73 citations

Evaluation of mild acute infectious myocarditis.

1982 • 73 citations

Assignment of patients into the classification of cardiomyopathies.

1992 • 73 citations

The morbid anatomy of experimental Coxsackie virus infection.

1951 • 73 citations

Genomic Detection of Enteroviruses in The Myocardium. Studies on animal hearts with coxsackievirus B3 myocarditis and endomyocardial biopsies from patients with myocarditis and dilated cardiomyopathy.

1992 • 72 citations

Requirement for Tyrosine Kinase p56^lckfor Thymic Development of Transgenic γδ T Cells

1993 • 71 citations

Clinical and Experimental Studies on Cardiomyopathy

1975 • 71 citations

Epitopes Shared between Coxsackievirus B3 (CVB3) and Normal Heart Tissue Contribute to CVB3-Induced Murine Myocarditis

1993 • 71 citations

A Mouse Model of Dilated-Type Cardiomyopathy Due to Coxsackievirus B3

1981 • 70 citations

Assessment of Cell-Mediated Hypersensitivity against Coxsackievirus B3 Viral-Induced Myocarditis Utilizing Hypertonic Salt Extracts of Cardiac Tissue

1978 • 70 citations

Prevalence of overt dilated cardiomyopathy in two regions of England.

1985 • 69 citations

Protective effect of recombinant alpha interferon on coxsackievirus B3 myocarditis in mice

1988 • 66 citations

Aggravation of coxsackievirus, group B, type 3-induced myocarditis and increase in cellular immunity to myocyte antigens in pregnant Balb/c mice and animals treated with progesterone

1984 • 66 citations

Detection of enteroviral ribonucleic acid in myocardial biopsies from patients with idiopathic dilated cardiomyopathy by polymerase chain reaction

1993 • 65 citations

Demonstration of coxsackie virus RNA in formalin‐fixed tissue sections from childhood myocarditis cases by in situ hybridization and the polymerase chain reaction

1993 • 65 citations

Coxsackievirus B3 murine myocarditis: deleterious effects of nonsteroidal anti-inflammatory agents.

1986 • 64 citations

Beta-blocker treatment of dilated cardiomyopathy. Beneficial effect of carteolol in mice.

1991 • 64 citations

Selection of an attenuated Coxsackievirus B3 variant, using a monoclonal antibody reactive to myocyte antigen

1991 • 64 citations

Prevention of viral myocarditis with recombinant human leukocyte interferon α A/D in a murine model

1987 • 64 citations

Effects of interleukin 2 on cardiac function in the isolated rat heart.

1990 • 63 citations

The role of myocarditis in end-stage dilated cardiomyopathy.

1987 • 63 citations

A Clinicopathologic Description of Myocarditis

1993 • 61 citations

Synergistic Interaction of Interferon- and Interferon- in Coxsackievirus B3-Infected Carrier Cultures of Human Myocardial Fibroblasts

1992 • 61 citations

Ameliorating Effect of IFN-β and Anti-IFN-β on Coxsackievirus B3-Induced Myocarditis in Mice

1985 • 60 citations

Five-year follow-up study of cases suggestive of acute myocarditis

1966 • 60 citations

The Impact of Recombinant DNA Technology on the Study of Enterovirus Heart Disease

1988 • 59 citations

Monoclonal antibody that inhibits infection of HeLa and rhabdomyosarcoma cells by selected enteroviruses through receptor blockade

1986 • 58 citations

“Acute pericarditis”: Myocardial enzyme release as evidence for myocarditis

1986 • 57 citations

Mapping of the RD phenotype of the Nancy strain of coxsackievirus B3

1992 • 57 citations

The Influence of Quantitated Post-Weaning Undernutrition on Coxsackievims B3 Infection of Adult Mice. II. Alteration of Host Defense Mechanisms

1970 • 57 citations

The role of enterovirus replication in the development of acute and chronic heart muscle disease in different immunocompetent mouse strains.

1993 • 57 citations

The natural history of encephalomyocarditis virus-induced myositis and myocarditis in mice. Viral persistence demonstrated by in situ hybridization.

1988 • 56 citations

Effects of Exercise on Goxsackie A9 Myocarditis in Adult Mice.

1964 • 56 citations

Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase

1991 • 56 citations

Evidence of perforin‐mediated cardiac myocyte injury in acute murine myocarditis caused by coxsackie virus B3

1993 • 55 citations

Differences in cytolytic T cell response of BALB/c mice infected with myocarditic and non-myocarditic strains of coxsackievirus group B, type 3

1983 • 55 citations

Detection of persistent coxsackie B virus RNA in dilated cardiomyopathy and myocarditis

1987 • 55 citations

Peripartum cardiomyopathy

1985 • 55 citations

IMMUNOLOGICAL REACTIONS OF THE COXSACKIE VIRUSES

1950 • 54 citations

MYOCARDITIS IN EXPERIMENTAL COXSACKIE B-3 INFECTION

1959 • 54 citations

Coxsackievirus-B3-induced myocarditis: virus receptor antibodies modulate myocarditis.

1989 • 53 citations

Heat-shock protein induction in adriamycin and picornavirus-infected cardiocytes.

1992 • 53 citations

Clinical outcome and left ventricular function 23 years after acute Coxsackie virus myopericarditis

1990 • 53 citations

Lack of Correlation between Neutralizing Antibody Production and Suppression of Coxsackievirus B-3 Replication in Target Organs: Evidence for Involvement of Mononuclear Inflammatory Cells in Host Defense

1979 • 53 citations

Molecular studies on enteroviral heart disease: patterns of acute and persistent infections

1991 • 53 citations

Generation of cytotoxic T lymphocytes during coxsackievirus B-3 infection. III. Role of sex.

1977 • 52 citations

Generation of Cytotoxic T Lymphocytes during Coxsackievirus B-3 Infection

1977 • 52 citations

Molecular Mechanisms in the Pathogenesis of Enteroviral Heart Disease: Acute and Persistent Infections

1993 • 51 citations

New approach to the estimation of the extent of myocardial fibrosis in patients with dilated cardiomyopathy: Use of signal-averaged electrocardiography

1993 • 51 citations

Primary antibody responses to a well-defined and unique hapten are not enhanced by preimmunization with carrier: analysis in a viral model.

1986 • 50 citations

Cardiac myosin-induced myocarditis as a model of postinfectious autoimmunity

1991 • 50 citations

Functional diversity in vascular endothelial cells: role in coxsackievirus tropism

1990 • 49 citations

Influence of anti-beta-receptor antibodies on cardiac adenylate cyclase in patients with idiopathic dilated cardiomyopathy

1990 • 49 citations

The occurrence in nature of the Coxsackie and ECHO viruses.

1961 • 49 citations

Effects of the immunomodulator LS 2616 on lymphocyte subpopulations in murine Coxsackievirus B3 myocarditis.

1989 • 49 citations

Assessment of cell-mediated immunity against coxsackievirus B3-induced myocarditis in a primate model (Papio papio)

1981 • 48 citations

Cardiovascular lipid accumulation with Coxsackie B virus infection in mice.

1990 • 48 citations

Isolation of a Coxsackie virus group B, type 5, from the heart of a fatal case of myocarditis in an adult

1969 • 48 citations

Maternal and Neonatal Infection with Coxsackievirus

1980 • 47 citations

SPECIFIC VIRAL INTERFERENCE IN HELA CELL CULTURES CHRONICALLY INFECTED WITH COXSACKIE B5 VIRUS

1963 • 46 citations

Peripheral T cells in mice lacking p56lck do not express significant antiviral effector functions.

1993 • 46 citations

Polyclonal immunoglobulin therapy protects against cardiac damage in experimental coxsackievirus-induced myocarditis

1992 • 46 citations

Coxsackievirus B3-induced myocarditis. Autoimmunity is L3T4+ T helper cell and IL-2 independent in BALB/c mice.

1987 • 45 citations

Aspects on the serodiagnosis of enterovirus infections by ELISA

1990 • 44 citations

Sex-related differences in the rapid production of cytotoxic spleen cells active against uninfected myofibers during Coxsackievirus B-3 infection.

1981 • 44 citations

Vaccination of Balb/c mice against enteroviral mediated myocarditis

1990 • 44 citations

Myocarditis: Unresolved issues in diagnosis and treatment

1990 • 44 citations

Pathogenetic differences between coxsackie A and B virus infections in newborn mice

1993 • 44 citations

Occurrence and significance of myocarditis in trauma.

1970 • 44 citations

Animal models of picornavirus-induced autoimmune disease: their possible relevance to human disease.

1990 • 44 citations

SUSCEPTIBILITY OF GRAVID MICE TO COXSACKIE VIRUS INFECTION

1954 • 43 citations

The epidemiology of viral heart disease.

1993 • 42 citations

THE AGE FACTOR IN EXPERIMENTAL COXSACKIE B-3 INFECTION

1959 • 41 citations

High yield production of an inactivated coxsackie B3 adjuvant vaccine with protective effect against experimental myocarditis.

1993 • 41 citations

Evolving concepts of cause, consequence, and control in myocarditis

1991 • 41 citations

Fractionation and Immunologic Assessment of KCl-Extracted Cardiac Antigens in Coxsackievirus B3 Virus-Induced Myocarditis

1979 • 41 citations

New concepts in viral heart disease

1989 • 41 citations

Persistence of viral genome into late stages of murine myocarditis detected by polymerase chain reaction.

1992 • 41 citations

Anti-coxsackievirus B3 neutralizing antibodies with pathological potential

1991 • 41 citations

Identification of a putative shared epitope between Coxsackie virus B4 and alpha cardiac myosin heavy chain

1991 • 40 citations

The Role of T Cells in Myosin-Induced Autoimmune Myocarditis

1993 • 40 citations

The mitochondrium as antigen in inflammatory heart disease

1987 • 40 citations

Immunomodulating therapy in viral myocarditis: Effects of tumour necrosis factor, interleukin 2 and anti-interleukin-2 receptor antibody in an animal model

1991 • 39 citations

Generation of Cytotoxic T Lymphocytes during Coxsackievirus B-3 Infection

1977 • 39 citations

Characterization of a cell culture persistently infected with the DA strain of Theiler's murine encephalomyelitis virus

1982 • 39 citations

Failure to demonstrate enterovirus aetiology in Swedish patients with dilated cardiomyopathy

1993 • 38 citations

Secondary enterovirus infection in the murine model of myocarditis

1990 • 38 citations

Virus-like particles in the heart of a patient with cardiomyopathy

1965 • 38 citations

T Cells in Cardiac Myosin-Induced Myocarditis

1993 • 37 citations

Acute Non-Rheumatic Myopericarditis: A Follow-up Study

1970 • 37 citations

Quantitation of enteroviral RNA by competitive polymerase chain reaction

1993 • 37 citations

Evaluation of the effects of low molecular weight heparin on inflammation and collagen deposition in chronic coxsackievirus B3-induced myocarditis in A/J mice.

1992 • 36 citations

Murine cell-mediated immune response recognizes an enterovirus group-specific antigen(s)

1989 • 36 citations

Sex-related differences in the pattern of coxsackievirus B-3-induced immune spleen cell cytotoxicity against virus-infected myofibers

1981 • 36 citations

Mechanisms of Action of Cyclosporine: Considerations for the Treatment of Autoimmune Diseases

1993 • 36 citations

The antigenic characteristics and the significance of the adenine nucleotide translocator as a major autoantigen to antimitochondrial antibodies in dilated cardiomyopathy.

1985 • 36 citations

Coxsackievirus-induced disease. CD4+ cells initiate both myocarditis and pancreatitis in DBA/2 mice.

1989 • 35 citations

Factors Influencing Host-Virus Interactions. II. Alteration of Coxsackie Virus Infection in Adult Mice by Cold.

1956 • 34 citations

Immunosuppression with high doses of cyclophosphamide reduces the severity of myocarditis but increases the mortality in murine Coxsackievirus B3 myocarditis.

1990 • 34 citations

Expression of MHC class I and II antigens and the II-2 receptor in rejection, myocarditis and dilated cardiomyopathy

1991 • 33 citations

AGE AND SUSCEPTIBILITY OF MICE TO COXSACKIE A VIRUSES

1962 • 33 citations

Myocardial fibrin deposition in experimental viral myocarditis that progresses to dilated cardiomyopathy.

1993 • 33 citations

IMMUNOLOGICAL REACTIONS OF THE COXSACKIE VIRUSES

1950 • 33 citations

Coxsackievirus B3 Persistence and Myocarditis in N:NIH(S) II nu/nu and +/nu Mice

1984 • 33 citations

Coxsackievirus B3 infection alters plasma membrane of neonatal skin fibroblasts

1986 • 33 citations

Progressive interstitial collagen deposition in Coxsackievirus B3-induced murine myocarditis.

1990 • 33 citations

Coxsackie B3 Myocarditis in Athymic Mice

1981 • 32 citations

Coxsackie B-3 Virus Infection in the Pregnant Mouse

1967 • 32 citations

Pathology of heart diseases of undetermined etiology which occur in Cali, Colombia

1963 • 31 citations

Heart disease in blacks of Africa and the Caribbean.

1991 • 31 citations

Coronary microvascular narrowing in acute murine coxsackie B3 myocarditis

1989 • 30 citations

Coxsackie virus heart disease: 15 years after

1988 • 30 citations

Coxsackievirus B infection in pregnant mice and transplacental infection of the fetus

1982 • 30 citations

Levamisole exacerbates coxsackievirus B3-induced murine myocarditis

1983 • 29 citations

α-Helical Coiled-Coil Molecules: A Role in Autoimmunity against the Heart

1993 • 29 citations

Protective Effect of Interferon on Infections with Hand, Foot, and Mouth Disease Virus in Newborn Mice

1986 • 29 citations

A neutralizing monoclonal antibody against Coxsackievirus B4 cross-reacts with contractile muscle proteins

1990 • 29 citations

Mapping of Antigenic Determinants of the Adenine-Nucleotide Translocator and Coxsackie B3 Virus with Synthetic Peptides: Use for the Diagnosis of Viral Heart Disease

1993 • 29 citations

Molecular cloning and partial characterization of the coxsackievirus B3 genome

1985 • 28 citations

What lessons can be learned from animal model studies in viral heart disease?

1993 • 28 citations

An attenuated variant of Coxsackievirus B3 preferentially induces immunoregulatory T cells in vivo

1991 • 28 citations

Chronic neonatal coxsackie myocarditis.

1989 • 28 citations

FATAL MYOCARDITIS IN AN ADOLESCENT CAUSED BY COXSACKIE VIRUS, GROUP B, TYPE FOUR

1965 • 27 citations

In vitro culture of coxsackievirus group B, type 3 immune spleen cells on infected endothelial cells and biological activity of the cultured cells in vivo

1984 • 27 citations

Effect of delayed captopril therapy on left ventricular mass and myonecrosis during acute coxsackievirus murine myocarditis

1990 • 27 citations

Treatment of experimental murine coxsackie B3 myocarditis

1991 • 27 citations

Perinatal Transmission of Coxsackievirus B3 in Mice

1987 • 27 citations

Generation of Cytotoxic T Lymphocytes during Coxsackievirus B-3 Infection

1977 • 26 citations

Die chronische Chagaskardiopathie

1957 • 26 citations

Virological study of idiopathic cardiomyopathy. Serological study of virus antibodies and immunofluorescent study of myocardial biopsies.

1981 • 26 citations

Coxsackievirus B4 infection of the mouse pancreas: the role of natural killer cells in the control of virus replication and resistance to infection

1992 • 26 citations

QUANTITATIVE STUDIES OF THE VIRUS-HOST RELATIONSHIP IN CHIMPANZEES AFTER INAPPARENT INFECTION WITH COXSACKIE VIRUSES

1953 • 25 citations

Virus Investigations in Heart Muscle Disease

1984 • 24 citations

Clearance of a Persistent Human Enterovirus Infection of the Mouse Central Nervous System by the Antiviral Agent Disoxaril

1989 • 24 citations

Detection of acute myocarditis using nuclear magnetic resonance imaging

1987 • 24 citations

The relationship of myocarditis to dilated cardiomyopathy

1984 • 23 citations

Effects of the antiviral WIN 54954 and the immune modulator LS 2616 on cachectin/TNF and gamma-interferon responses during viral heart disease.

1993 • 23 citations

Demonstration of suppressor cells in coxsackievirus group B, type 3 infected female Balb/c mice which prevent myocarditis

1986 • 22 citations

Experimental infections with coxsackie viruses

1961 • 21 citations

Progress and challenges in the pathological diagnosis of myocarditis

1991 • 21 citations

Coxsackievirus B-3-induced myocarditis. Virus and actinomycin D treatment of myocytes induces novel antigens recognized by cytolytic T lymphocytes.

1988 • 21 citations

Persistent infection of rat insulinoma cells with Coxsackie B4 virus

1986 • 21 citations

Lyme myocarditis diagnosed by indium-111-antimyosin antibody scintigraphy

1989 • 21 citations

Toward understanding the pathogenesis of enterovirus-induced cardiomyopathy: Molecular and ultrastructural approaches

1990 • 20 citations

Lipopolysaccharide suppresses cytokine release from coxsackie virus-infected human monocytes

1992 • 20 citations

Multiplication of Coxsackie virus in adult mice exposed to roentgen radiation.

1953 • 20 citations

Non-cytopathic infection of rhabdomyosarcoma cells by coxsackie B5 virus

1992 • 19 citations

Transplacental infection of the mouse fetus by Coxsackie viruses.

1969 • 19 citations

Cellular and Molecular Bases for the Immunopathology of the Myocardial Cell Damage Involved in Acute Viral Myocarditis with Special Reference to Dilated Cardiomyopathy.

1992 • 19 citations

Role of antiviral antibodies in resistance against coxsackievirus B3 infection: interaction between preexisting antibodies and an interferon inducer

1982 • 19 citations

Technetium-99m stannous pyrophosphate myocardial scintigrams in pericardial disease

1980 • 19 citations

Evolution of the Placental Barrier to Fetal Infection by Murine Enteroviruses

1991 • 19 citations

Studies in myocarditis. IV. Late prognosis.

1965 • 19 citations

Modification of Severe Coxsackievirus B ₃ Infection in Marasmic Mice by Transfer of Immune Lymphoid Cells

1971 • 19 citations

Naturally occurring anti-idiotypic antibodies--mechanisms for autoimmunity and immunoregulation?

1991 • 18 citations

Effect of cardiac transplantation on anti-beta-receptor antibodies in idiopathic dilated cardiomyopathy

1989 • 18 citations

Molecular cloning of a heart antigen that cross-reacts with a neutralizing antibody to coxsackievirus B4

1991 • 18 citations

Interstitial Connective Tissue Matrix Alterations in Acute Murine Chagas' Disease

1993 • 18 citations

Clinical diagnosis of myocarditis and dilated cardiomyopathy.

1993 • 17 citations

Immunomodulating factors and immunosuppressive drugs in the therapy of myocarditis.

1993 • 17 citations

Therapy of coxsackie virus B3-induced myocarditis with WIN 54954 in different formulations.

1993 • 17 citations

Organ Culture of Human Aorta: Prolonged Survival with Support of Viral Replication

1975 • 17 citations

Multiplication of Coxsackie Virus in Adult Mice Exposed to Roentgen Radiation

1953 • 17 citations

Induction of heterotypic virus resistance in adult inbred mice immunized with a variant of Coxsackievirus B3

1990 • 17 citations

Increased transcription of interleukin-6 in the brains of mice with chronic enterovirus infection

1993 • 16 citations

Demonstration of a Barrier to Transplacental Passage of Murine Enteroviruses in Late Gestation

1989 • 16 citations

Studies in Myocarditis

1965 • 16 citations

Natural history of coxsackievirus B3-induced myocarditis in ACA/Sn mice: viral persistence demonstrated by quantitative in situ hybridization histochemistry

1991 • 16 citations

Acute viral myocarditis. Clinical and histologic changes.

1979 • 16 citations

Pathogenesis and preventive and therapeutic trials in an animal model of dilated cardiomyopathy induced by a virus.

1987 • 16 citations

Incidence of dilated cardiomyopathy

1985 • 16 citations

Modulation of Murine Coxsackievirus-Induced Myocarditis Utilizing Anti-Idiotypes

1987 • 15 citations

An experimental approach to virus myocarditis.

1965 • 15 citations

Phenotypic and genotypic differences among naturally occuring coxsackie virus B3 variants

1987 • 15 citations

Effect of antireceptor antibodies in dilated cardiomyopathy on the cycling of cardiac beta receptors

1991 • 15 citations

Enteroviral infection in end stage dilated cardiomyopathy

1990 • 15 citations

Natural History of Acute Viral or Idiopathic Myocarditis: A Clinical and Endomyocardial Biopsy Follow-up

1988 • 15 citations

Evolution of coxsackie B virus during in vitro persistent infection: Detection of protein mutations using two‐dimensional polyacrylamide gel electrophoresis

1993 • 14 citations

Cardiomyopathies and specific heart muscle diseases. Definitions, terminology, classifications and new and old approaches.

1992 • 14 citations

Immunosuppressives in murine myocarditis

1987 • 14 citations

Cultured human heart cells: a model system for the study of the antiviral activity of interferons

1987 • 14 citations

Immune-Mediated Modulation of β-Adrenoceptor Function in Human Dilated Cardiomyopathy

1993 • 14 citations

Induction of cytokine release from human monocytes by coxsackievirus infection

1991 • 14 citations

Study of the Pericardium and Ventricular Myocardium

1963 • 14 citations

Infection of Cynomolgus Monkeys with the Ohio Type of Coxsackie Virus (C Virus)

1950 • 13 citations

Cellular immune responses in mice challenged with an amyocarditic variant of coxsackievirus B3

1985 • 13 citations

Characterization of a YAC-1 mouse cell receptor for group B coxsackieviruses

1989 • 13 citations

Interferon and natural killer cell activity in coxsackie virus B3-induced murine myocarditis

1987 • 13 citations

The value of endomyocardial biopsies in myocarditis and dilated cardiomyopathy

1991 • 13 citations

Autoantibodies Against the Adenine Nucleotide Translocator in Myocarditis and Dilated Cardiomyopathy

1984 • 12 citations

Myocardial indium-111 antimyosin uptake in patients with idiopathic dilated cardiomyopathy: its relation to haemodynamics, histomorphometry, myocardial enteroviral infection, and clinical course

1993 • 12 citations

Viruses and myocarditis

1972 • 12 citations

Genetic Analysis of Dilated Cardiomyopathy. HLA and immunoglobulin genes may confer susceptibility.

1992 • 12 citations

Antimyocarditic activity of the guanine derivative BIOLF-70 in a coxsackievirus B3 murine model

1985 • 12 citations

Coxsackie A9 Myocarditis in Adult Mice.

1962 • 11 citations

Discovery and development of antipicornaviral agents.

1993 • 11 citations

Monoclonal anti-idiotypic antibodies regulate the expression of virus-induced murine myocarditis

1989 • 10 citations

Indirect inhibition of myocyte RNA and protein synthesis by interleukin-1

1990 • 10 citations

Vascular HLA-DR Expression Correlates with Pathologic Changes Suggestive of Ischemia in Idiopathic Dilated Cardiomyopathy

1993 • 10 citations

Influence of sex hormones on coxsackie virus group B, type 3 induced myocarditis in Balb/c mice

1987 • 10 citations

Coxsackie B4 viral myocarditis causing ventricular aneurysm

1990 • 10 citations

Experimental study of virus myocarditis in culture.

1979 • 10 citations

Mimicry of Heart Cell Surface Epitopes in Primary Anti-Trypanosoma cruzi Lyt 2+ T Lymphocytes

1993 • 10 citations

Impaired myocyte function in vitro incubated with sera from patients with myocarditis

1991 • 10 citations

Animal Models for Therapeutic Trials of Viral Myocarditis: Effect of Ribavirin and Alpha Interferon on Coxsackievirus B3 and Encephalomyocarditis Virus Myocarditis

1988 • 10 citations

Genetics of Coxsackie B3 (CVB3) myocarditis

1991 • 10 citations

Polyclonal Anti-ldiotypes Influence Macrophage Chemotaxis in Coxsackievirus-lnduced Murine Myocarditis

1989 • 9 citations

Congestive Cardiomyopathy

2001 • 9 citations

Mechanisms of group B coxsackie virus persistence in human cells

1987 • 8 citations

Myocarditis and perimyocarditis. Historical survey, epidemiology and clinical features

1987 • 8 citations

Multiplication of Boston Strains of Coxsackievirus A9 in the Adult Mouse Heart

1965 • 7 citations

Experimental animal models of viral myocarditis

1987 • 7 citations

Etiology, Pathogenesis, and Pathophysiology of Dilated Cardiomyopathies

1988 • 7 citations

De novo expression of MHC class I and class II antigens on endomyocardial biopsies from patients with inflammatory heart disease and rejection following heart transplantation

1993 • 7 citations

Observations on the Course of Coxsackie A-9 Myocarditis in C3H Mice.

1963 • 6 citations

Virus-Induced Autoimmunity: Cross-Reactivity of Antiviral Antibodies with Self-Components

1988 • 6 citations

Viral Heart Disease — A Precursor of Congestive Cardiomyopathy

1984 • 6 citations

Genotypic and serotypic profile in dilated cardiomyopathy.

1993 • 6 citations

Histomorphological Relations Between Myocarditis and Dilated Cardiomyopathy

1984 • 5 citations

Morphological recognition of viral heart disease.

1993 • 5 citations

Current profile of the professional activities of the American cardiologist

1974 • 5 citations

IgG antibodies to asialoGM1 are more sensitive than IgM antibodies to kill in vivo natural killer cells and prematured cytotoxic T lymphocytes of mouse spleen.

1990 • 4 citations

Murine coxsackie virus B3 myocarditis

1987 • 4 citations

Synergism between Adriamycin and Coxsackie Virus Group B Type 3 (CVB3) in Induction of Myocardial Injury: Potential Role for γ/δ TcR+ T Lymphocytes in Pathogenesis

1993 • 4 citations

Anti-idiotype-Pulsed B Cells in the Induction and Expression of Autoimmune Myocarditis

1993 • 4 citations

Myocardial gallium-67 imaging in dilated cardiomyopathy

1985 • 4 citations

The Role of Interferon in Picornavirus Infections

1988 • 4 citations

Altered distribution of heavy metals and lipids in coxsackievirus B3 infected mice.

1993 • 4 citations

Modelling of the tertiary structure of coxsackievirus B3 from the structure of poliovirus and rhinovirus.

1993 • 3 citations

Studies on the mechanism(s) of resistance to coxsackie virus B3 (CVB3)-induced myocarditis at adolescence in mice vaccinated at birth with a temperature-sensitive mutant of CVB3

1987 • 2 citations

Effect of mediators on coronary circulation

1991 • 1 citations

A mouse model of coxsackievirus myocarditis.

1992 • 1 citations

Deleted Work

1955 • 0 citations