Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

A rapid and simple method for preparation of RNA fromSaccharomyces cerevisiae

1990 • 1,340 citations

Laboratory course manual for methods in yeast genetics

1986 • 1,310 citations

Interaction of antibiotics with functional sites in 16S ribosomal RNA

1987 • 1,143 citations

Compilation of small ribosomal subunit RNA sequences

1992 • 985 citations

Unusual Resistance of Peptidyl Transferase to Protein Extraction Procedures

1992 • 725 citations

Collection of small subunit (16S- and 16S-like) ribosomal RNA structures: 1994

1994 • 533 citations

The Ribosome : structure, function, and evolution

1990 • 508 citations

RIBOSOMAL RNA AND TRANSLATION

1991 • 489 citations

Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

1990 • 376 citations

[13] Eviction and transplacement of mutant genes in yeast

1983 • 305 citations

A functional pseudoknot in 16S ribosomal RNA.

1991 • 287 citations

Vector systems for the expression, analysis and cloning of DNA sequence in S. cerevisiae

1985 • 265 citations

Phenotypic suppression and misreading in Saccharomyces cerevisiae

1979 • 235 citations

Phenotypic suppression of nonsense mutants in yeast by aminoglycoside antibiotics

1979 • 231 citations

A chemiluminescent assay for quantitation of β-galactosidase in the femtogram range: Application to quantitation of β-galactosidase in lacZ-transfected cells

1991 • 223 citations

The nucleotide sequence of the 17S ribosomal RNA gene of Tetrahymena thermophila and the identification of point mutations resulting in resistance to the antibiotics paromomycin and hygromycin.

1985 • 198 citations

[46] Antibiotic resistance mutations in ribosomal RNA genes of Escherichia coli

1988 • 187 citations

Synthesis of large rRNAs by RNA polymerase II in mutants of Saccharomyces cerevisiae defective in RNA polymerase I.

1991 • 174 citations

Three widely separated positions in the 16S RNA lie in or close to the ribosomal decoding region; a site-directed cross-linking study with mRNA analogues.

1992 • 132 citations

Mutant 16S ribosomal RNA: a codon-specific translational suppressor.

1988 • 110 citations

An accuracy center in the ribosome conserved over 2 billion years.

1993 • 104 citations

E. coli ribosomes with a C912 to U base change in the 16S rRNA are streptomycin resistant.

1986 • 104 citations

A mutation in the 530 loop ofEscherichia coli16S ribosomal RNA causes resistance to streptomycin

1988 • 94 citations

A ribosomal ambiguity mulation in the 530 loop ofE.coli16S rRNA

1992 • 90 citations

Ribosome Biogenesis in Yeast

1991 • 88 citations

A system for the analysis of yeast ribosomal DNA mutations.

1989 • 86 citations

Streptomycin-resistance ofEuglena gracilischloroplasts: identification of a point mutation in the 16S rRNA gene in an invariant position

1985 • 86 citations

Quantitation of readthrough of termination codons in yeast using a novel gene fusion assay

1991 • 85 citations

Mutants of the elongation factor EF-Tu, a new class of nonsense suppressors.

1985 • 82 citations

Substitution of an invariant nucleotide at the base of the highly conserved ‘530–loop’ of 15S rRNA causes suppression of yeast mitochondrial ochre mutations

1989 • 66 citations

A system to study transcription by yeast RNA polymerase I within the chromosomal context: functional analysis of the ribosomal DNA enhancer and the RBP1/REB1 binding sites.

1992 • 64 citations

23S Ribosomal RNA mutations in halobacteria conferring resistance to the anti-80S ribosome targeted antibiotic anisomycin

1987 • 63 citations

Mapping of chloroplast mutations conferring resistance to antibiotics in Chlamydomonas: Evidence for a novel site of streptomycin resistance in the small subunit rRNA

1988 • 62 citations

The yeast nuclear geneMRF1encodes a mitochondrial peptide chain release factor and cures several mitochondrial RNA splicing defects

1992 • 51 citations

Mutations in the 915 region ofEscherichia coli16S ribosomal RNA reduce the binding of streptomycin to the ribosome

1991 • 47 citations

The yeast omnipotent suppressor SUP46 encodes a ribosomal protein which is a functional and structural homolog of the Escherichia coli S4 ram protein.

1992 • 40 citations

tRNA-rRNA interactions and peptidyl transferase.

1993 • 35 citations

A System for the Analysis of Yeast Ribosomal DNA Mutations

1989 • 33 citations

[Selective systems for obtaining recessive ribosomal suppressors in saccharomycete yeasts].

1988 • 29 citations

Interaction between 16S ribosomal RNA and ribosomal protein S12: differential effects of paromomycin and streptomycin

1991 • 25 citations

Selection of Ribosomal Mutants by Antibiotic Suppression in Yeast

1971 • 24 citations

Mitotic and meiotic gene conversion of Ty elements and other insertions in Saccharomyces cerevisiae.

1989 • 24 citations

The interaction between streptomycin and ribosomal RNA

1991 • 23 citations

[Change of some physiological requirements of yeasts as a result of adaptation to streptomycin].

1963 • 3 citations