The nucleotide sequence of the 17S ribosomal RNA gene of Tetrahymena thermophila and the identification of point mutations resulting in resistance to the antibiotics paromomycin and hygromycin.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

The 3′-Terminal Sequence of Escherichia coli 16S Ribosomal RNA: Complementarity to Nonsense Triplets and Ribosome Binding Sites

1974 • 3,603 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

Preparative and analytical purification of DNA from agarose.

1979 • 1,585 citations

STRUCTURE OF RIBOSOMAL RNA

1984 • 793 citations

How ribosomes select initiator regions in mRNA: base pair formation between the 3' terminus of 16S rRNA and the mRNA during initiation of protein synthesis in Escherichia coli.

1975 • 690 citations

The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid.

1984 • 425 citations

The structure of the yeast ribosomal RNA genes. I. The complete nucleotide sequence of the 18S ribosomal RNA gene from Saccharomyces cerevisiae

1980 • 348 citations

Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes ofEscherichia coli

1984 • 241 citations

Nucleotide sequence of Xenopus laevis 18S ribosomal RNA inferred from gene sequence

1981 • 210 citations

Covalent crosslinking of tRNA1Val to 16S RNA at the ribosomal P site: identification of crosslinked residues.

1982 • 203 citations

Identification of the paromomycin-resistance mutation in the 15 S rRNA gene of yeast mitochondria.

1982 • 188 citations

A single integrated gene for ribosomal RNA in a eucaryote, tetrahymena pyriformis

1977 • 167 citations

Altered ribosomal RNA genes in mitochondria from mammalian cells with chloramphenicol resistance

1981 • 154 citations

Protection of specific sites in 16 S RNA from chemical modification by association of 30 S and 50 S ribosomes

1977 • 151 citations

Mechanism of ribosomal subunit association: Discrimination of specific sites in 16 S RNA essential for association activity

1979 • 151 citations

The complete nucleotide sequence of the rat 18S ribosomal RNA gene and comparison with the respective yeast and frog genes

1983 • 145 citations

The Synthesis and Purification of [γ-32P]-Adenosine Triphosphate with High Specific Activity

1973 • 130 citations

Identification of two erythromycin resistance mutations in the mitochondrial gene coding for the large ribosomal RNA in yeast

1982 • 118 citations

THE GENETICS OF BACTERIAL RIBOSOMES

1972 • 111 citations

Aminoglycoside antibiotics and eukaryotic protein synthesis: structure-function relationships in the stimulation of misreading with a wheat embryo system

1978 • 109 citations

Mitochondrial DNA of chloramphenicol-resistant mouse cells contains a single nucleotide change in the region encoding the 3' end of the large ribosomal RNA.

1981 • 106 citations

Selection for Escherichia coli mutants with proteins missing from the ribosome

1979 • 100 citations

Mechanisms of action of aminoglycoside antibiotics in eucaryotic protein synthesis

1984 • 82 citations

Mistranslation in a eucaryotic organism

1978 • 81 citations

Single extrachromosomal ribosomal rna gene copies are synthesized during amplification of the rDNA in tetrahymena

1981 • 76 citations

Extrachromosomal ribosomal RNA genes in Tetrahymena structure and evolution

1979 • 70 citations

Allele-specific, selective amplification of a ribosomal RNA gene in tetrahymena thermophila

1982 • 69 citations

Localization of transcribed regions on extrachromosomal ribosomal RNA genes of Tetrahymena thermophila by R-loop mapping.

1979 • 66 citations

Fidelity of the eukaryotic codon-anticodon interaction: interference by aminoglycoside antibiotics

1984 • 58 citations

Primary structure of rabbit 18S ribosomal RNA determined by direct RNA sequence analysis

1984 • 51 citations

The nucleotide sequence of the 16S ribosomal RNA gene of the archaebacterium Halococcus morrhua.

1984 • 50 citations

Nuclease mapping of the secondary structure of the 49-nucleotide 3' terminal cloacin fragment ofEscherichia coli16S RNA and its interactions with initiation factor 3

1983 • 41 citations

Secondary structure of tbeDictyostelium discoideumsmall subunit ribosomal RNA

1983 • 39 citations

Functional conservation near the 3' end of eukaryotic small subunit RNA: photochemical crosslinking of P site-bound acetylvalyl-tRNA to 18S RNA of yeast ribosomes.

1982 • 33 citations

Conservation of structure in ribosomal RNA

1984 • 25 citations

Photosensitized cross‐linking of IF‐3 to Escherichia coli 30 S subunits

1977 • 24 citations

Nucleotide sequence of the 5′-terminal coding region for pre-rRNA and mature 17S rRNA inTetrahymena thermophilarDNA

1984 • 21 citations

5'- and 3'-Terminal nucleotide sequences of Tetrahymena pyriformis 17S rRNA

1977 • 15 citations

Roles for ribosomal proteins

1983 • 6 citations