Localization of yeast RNA polymerase I core subunits by immunoelectron microscopy.

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

Antibody-selectable filamentous fd phage vectors: affinity purification of target genes

1988 • 863 citations

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

1985 • 855 citations

A Third Recognition Element in Bacterial Promoters: DNA Binding by the α Subunit of RNA Polymerase

1993 • 790 citations

[15] Libraries of peptides and proteins displayed on filamentous phage

1993 • 770 citations

Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases

1985 • 670 citations

Use of multivariate statistics in analysing the images of biological macromolecules

1981 • 579 citations

Crystal structure of bacteriophage T7 RNA polymerase at 3.3 Å resolution

1993 • 358 citations

Prokaryotic and eukaryotic RNA polymerases have homologous core subunits.

1987 • 355 citations

A unique structure at the carboxyl terminus of the largest subunit of eukaryotic RNA polymerase II.

1985 • 346 citations

Bipartite functional map of the E. coli RNA polymerase α subunit: Involvement of the C-terminal region in transcription activation by cAMP-CRP

1991 • 346 citations

Two-dimensional crystals of streptavidin on biotinylated lipid layers and their interactions with biotinylated macromolecules

1991 • 339 citations

Domain organization of RNA polymerase α subunit: C-terminal 85 amino acids constitute a domain capable of dimerization and DNA binding

1994 • 237 citations

GENETICS OF BACTERIAL RNA POLYMERASES

1979 • 192 citations

Three-dimensional structure of Escherichia coli RNA polymerase holoenzyme determined by electron crystallography

1989 • 189 citations

RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C

1987 • 184 citations

Three-dimensional structure of E. coil core RNA polymerase: Promoter binding and elongation conformations of the enzyme

1995 • 183 citations

Amino acid changes in conserved regions of the beta-subunit of Escherichia coli RNA polymerase alter transcription pausing and termination.

1990 • 162 citations

Three-dimensional structure of yeast RNA polymerase II at 16 Å resolution

1991 • 161 citations

Archaebacteria and eukaryotes possess DNA-dependent RNA polymerases of a common type.

1983 • 158 citations

Spot-immunodetection of conserved determinants in eukaryotic RNA polymerases. Study with antibodies to yeast RNA polymerases subunits.

1982 • 129 citations

RPA190, the gene coding for the largest subunit of yeast RNA polymerase A.

1988 • 124 citations

RPC19, the gene for a subunit common to yeast RNA polymerases A (I) and C (III)

1991 • 118 citations

Orientation and topography of RNA polymerase III in transcription complexes.

1993 • 117 citations

Immunological studies of yeast nuclear RNA polymerases at the subunit level.

1980 • 116 citations

Interactions between three common subunits of yeast RNA polymerases I and III.

1993 • 114 citations

A cinematographic view of Escherichia coli RNA polymerase translocation.

1989 • 108 citations

Studies on the functional topography of Escherichia coli RNA polymerase

1987 • 103 citations

Studies of the functional topography of Escherichia coli RNA polymerase

1989 • 100 citations

Localization of an alpha-amanitin resistance mutation in the gene encoding the largest subunit of mouse RNA polymerase II.

1987 • 97 citations

E.coliRNA polymerase, deleted in the C-terminal part of its α-subunit, interacts differently with the cAMP-CRP complex at thelacP1 and at thegaP1 promoter

1993 • 94 citations

RNA Polymerase II Subunit RPB3 Is an Essential Component of the mRNA Transcription Apparatus

1989 • 91 citations

Termination-altering amino acid substitutions in the beta' subunit of Escherichia coli RNA polymerase identify regions involved in RNA chain elongation.

1994 • 91 citations

A mutation in the largest subunit of RNA polymerase II alters RNA chain elongation in vitro.

1985 • 87 citations

Suppressor analysis of temperature-sensitive mutations of the largest subunit of RNA polymerase I in Saccharomyces cerevisiae: a suppressor gene encodes the second-largest subunit of RNA polymerase I.

1991 • 85 citations

Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes.

1985 • 82 citations

Three-dimensional model of yeast RNA polymerase I determined by electron microscopy of two-dimensional crystals.

1993 • 80 citations

Conditional Mutations Occur Predominantly in Highly Conserved Residues of RNA Polymerase II Subunits

1990 • 78 citations

The RET1 gene of yeast encodes the second-largest subunit of RNA polymerase III. Structural analysis of the wild-type and ret1-1 mutant alleles.

1991 • 77 citations

Zinc-binding subunits of yeast RNA polymerases.

1991 • 75 citations

A universally conserved region of the largest subunit participates in the active site of RNA polymerase III.

1995 • 73 citations

Active site labeling of the RNA polymerases A, B, and C from yeast.

1987 • 72 citations

Alpha: the Cinderella subunit of RNA polymerase.

1992 • 71 citations

Mapping of linear epitopes recognized by monoclonal antibodies with gene-fragment phage display libraries

1995 • 67 citations

Role of Escherichia coli RNA polymerase alpha subunit in modulation of pausing, termination and anti-termination by the transcription elongation factor NusA.

1996 • 66 citations

Studies on the inhibition by α-amanitin of single-step addition reactions and productive RNA synthesis catalysed by wheat-germ RNA polymerase II

1989 • 54 citations

A conjugation-specific gene (cnjC) fromTetrahymenaencodes a protein homologous to yeast RNA polymerase subunits (RPB3, RPC40) and similar to a portion of the prokaryotic RNA polymerase a subunit (rpoA)

1990 • 50 citations

Mutations in a conserved region of RNA polymerase II influence the accuracy of mRNA start site selection.

1991 • 48 citations

Yeast RNA polymerase II subunit RPB11 is related to a subunit shared by RNA polymerase I and III.

1993 • 46 citations

Conditional expression of RPA190, the gene encoding the largest subunit of yeast RNA polymerase I: effects of decreased rRNA synthesis on ribosomal protein synthesis.

1990 • 42 citations

Analysis of yeast RNA polymerases with subunit-specific antibodies.

1983 • 41 citations

The Thumbs's Knuckle

1994 • 38 citations

Orientation and Topography of RNA Polymerase III in Transcription Complexes

1993 • 37 citations

Structural study of the yeast RNA polymerase A

1990 • 37 citations

Localization of an α-Amanitin Resistance Mutation in the Gene Encoding the Largest Subunit of Mouse RNA Polymerase II

1987 • 35 citations

Suppressor Analysis of Temperature-Sensitive Mutations of the Largest Subunit of RNA Polymerase I in Saccharomyces cerevisiae: a Suppressor Gene Encodes the Second-Largest Subunit of RNA Polymerase I

1991 • 33 citations

Probing yeast RNA polymerase A subunits with monospecific antibodies.

1982 • 32 citations

Interaction of nucleic acids with the DNA‐dependent RNA polymerases of Drosophila

1983 • 30 citations

Determination of lysine residues affinity labeled in the active site of yeast RNA polymerase II(B) by mutagenesis

1992 • 30 citations

NusA interferes with interactions between the nascent RNA and the C-terminal domain of the alpha subunit of RNA polymerase in Escherichia coli transcription complexes.

1995 • 27 citations

Three-Dimensional Immunoelectron Microscopy of Scorpion Hemocyanin Labeled with a Monoclonal Fab Fragment

1993 • 24 citations

The quaternary structure of Escherichia coli RNA polymerase studied with (scanning) transmission (immuno)electron microscopy

1983 • 22 citations

Mutations in a Conserved Region of RNA Polymerase II Influence the Accuracy of mRNA Start Site Selection

1991 • 22 citations

Conditional Expression of RPA190, the Gene Encoding the Largest Subunit of Yeast RNA Polymerase I: Effects of Decreased rRNA Synthesis on Ribosomal Protein Synthesis

1990 • 20 citations

Monoclonal antibodies directed against mammalian RNA polymerase I. Identification of the catalytic center.

1983 • 16 citations

Identification of a nucleic acid‐binding region within the largest subunit of Drosophila melanogaster RNA polymerase II

1993 • 11 citations

Localization of proteins L4, L5, L20 and L25 on the ribosomal surface by immuno-electron microscopy

1989 • 10 citations

Electron microscopic study of yeast RNA polymerase A: Analysis of single molecular images

1990 • 5 citations

Nucleic acid‐binding regions of the second‐largest subunit of Drosophila RNA polymerase II identified by Southwestern blotting

1994 • 4 citations

Conformational change of DNA binding subunit of RNA polymerase II on binding to DNA

1985 • 3 citations