NusA interferes with interactions between the nascent RNA and the C-terminal domain of the alpha subunit of RNA polymerase in Escherichia coli transcription complexes.

A Third Recognition Element in Bacterial Promoters: DNA Binding by the α Subunit of RNA Polymerase

1993 • 790 citations

The Harvey Lectures . Delivered under the Auspices of The Harvey Society of New York, 1906-4, by Professors A. E. Wright, C. A. Herter, W. T. Porter, J. G. Adami, F. G. Benedict, E. B. Wilson, George S. Huntington, W. T. Councilman, Friedrioh Muller and Dr. S. J. Meltzer. Pp. 1414 Philadelphia and London, J. B. Lippincott Company. 1908.

1908 • 422 citations

Protein-protein communication within the transcription apparatus

1993 • 366 citations

Transcription mechanisms and regulation

1994 • 299 citations

Domain organization of RNA polymerase α subunit: C-terminal 85 amino acids constitute a domain capable of dimerization and DNA binding

1994 • 237 citations

Transcription : mechanisms and regulation

1994 • 195 citations

Role of the RNA polymerase α subunit in transcription activation

1992 • 179 citations

Identification of the Target of a Transcription Activator Protein by Protein-Protein Photocrosslinking

1994 • 166 citations

New models for the mechanism of transcription elongation and its regulation.

1992 • 154 citations

Discontinuous Mechanism of Transcription Elongation

1994 • 145 citations

Assembly of transcription elongation complexes containing the N protein of phage lambda and the Escherichia coli elongation factors NusA, NusB, NusG, and S10.

1991 • 132 citations

Elongation by Escherichia coli RNA polymerase is blocked in vitro by a site-specific DNA binding protein.

1990 • 130 citations

Escherichia coli σ70 and NusA proteins

1991 • 114 citations

The Single-Nucleotide Addition Cycle in Transcription: a Biophysical and Biochemical Perspective

1992 • 105 citations

Glu-111 is required for activation of the DNA cleavage center of EcoRI endonuclease

1989 • 104 citations

Identification of a subunit assembly domain in the alpha subunit of Escherichia coli RNA polymerase

1991 • 86 citations

Topography of transcription: path of the leading end of nascent RNA through the Escherichia coli transcription complex.

1983 • 77 citations

Involvement of the RNA polymerase α subunit C‐terminal region in co‐operative interaction and transcriptional activation with OxyR protein

1993 • 72 citations

Direct interaction between two Escherichia coli transcription antitermination factors, NusB and ribosomal protein S10

1992 • 68 citations

[27] Photoaffinity cross-linking methods for studying RNA-protein interactions

1989 • 55 citations

Hydroxylamine cleavage of proteins in polyacrylamide gels

1983 • 49 citations

NusA contacts nascent RNA in Escherichia coli transcription complexes

1995 • 41 citations

Simultaneous gain and loss of functions caused by a single amino acid substitution in the beta subunit of Escherichia coli RNA polymerase: suppression of nusA and rho mutations and conditional lethality.

1992 • 32 citations

Active site labeling of Escherichia coli transcription elongation complexes with 5-[4-azidophenacyl)thio)uridine 5'-triphosphate.

1990 • 28 citations

Efficient modification ofE. coliRNA polymerasein vitroby theNgene transcription antitermination protein of bacteriophage lambda

1985 • 26 citations

Genetic interaction between the beta' subunit of RNA polymerase and the arginine-rich domain of Escherichia coli nusA protein

1991 • 26 citations

Synthesis and characterization of a new photocrosslinking CTP analog and its use in photoaffinity labelingE.coliand T7 RNA polymerases

1993 • 26 citations

Synthesis and characterization of 5-[(4-azidophenacyl)thio]uridine 5'-triphosphate, a cleavable photo-cross-linking nucleotide analog

1989 • 26 citations

RNA-protein interactions in a Nus a-containing Escherichia coli transcription complex paused at an RNA hairpin

1991 • 21 citations

Photo‐modification studies of the contacts of the 5′‐terminus of growing RNA with the subunits of RNA‐polymerase

1981 • 18 citations

NusA changes the conformation of Escherichia coli RNA polymerase at the binding site for the 3' end of the nascent RNA

1994 • 14 citations