A cinematographic view of Escherichia coli RNA polymerase translocation.

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

Hydroxyl radical "footprinting": high-resolution information about DNA-protein contacts and application to lambda repressor and Cro protein.

1986 • 518 citations

Cycling of ribonucleic acid polymerase to produce oligonucleotides during initiation in vitro at the lac UV5 promoter

1980 • 293 citations

The interaction of RNA polymerase and lac repressor with the lac control region

1979 • 283 citations

Transcription from efficient promoters can interfere with plasmid replication and diminish expression of plasmid specified genes.

1982 • 281 citations

A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes

1982 • 264 citations

Interaction of RNA polymerase with lacUV5 promoter DNA during mRNA initiation and elongation

1985 • 207 citations

Intermediates in transcription initiation from the E. coli lac UV5 promoter

1985 • 202 citations

A steady state assay for the RNA polymerase initiation reaction.

1978 • 194 citations

Mapping of SV40 DNA replication origin region binding sites for the SV40 T antigen by protection against exonuclease III digestion

1980 • 191 citations

Promoters: Structure and function

1983 • 186 citations

RNA polymerase unwinds an 11-base pair segment of a phage T7 promoter

1979 • 181 citations

Isolation and properties of transcribing ternary complexes of Escherichia coli RNA polymerase positioned at a single template base

1987 • 171 citations

Mapping of single-stranded regions in duplex DNA at the sequence level: single-strand-specific cytosine methylation in RNA polymerase-promoter complexes.

1983 • 164 citations

Functional dissection of Escherichia coli promoters: information in the transcribed region is involved in late steps of the overall process.

1986 • 159 citations

A New Method of Large Scale Preparation of Highly Purified DNA- Dependent RNA-Polymerase fromE. coli

1970 • 159 citations

Overexpression and purification of the sigma subunit of Escherichia coli RNA polymerase

1983 • 158 citations

Role of the sigma subunit of Escherichia coli RNA polymerase in initiation. II. Release of sigma from ternary complexes.

1980 • 143 citations

Topological unwinding of strong and weak promoters by RNA polymerase

1987 • 136 citations

A stressed intermediate in the formation of stably initiated RNA chains at the Escherichia coli lac UV5 promoter

1987 • 136 citations

Mapping and characterization of transcriptional pause sites in the early genetic region of bacteriophage T7

1987 • 129 citations

RNA polymerase interactions with the upstream region of the E. coli tyrT promoter

1983 • 93 citations

Topography of transcription: path of the leading end of nascent RNA through the Escherichia coli transcription complex.

1983 • 77 citations

Structure and Function ofE. ColiPromoter DN

1987 • 72 citations

Interaction of Escherichia coli RNA polymerase with DNA in an elongation complex arrested at a specific psoralen crosslink site

1988 • 68 citations

One-dimensional diffusion of Escherichia coli DNA-dependent RNA polymerase: a mechanism to facilitate promoter location.

1988 • 61 citations

DNA-dependent RNA polymerase of Escherichia coli induces bending or an increased flexibility of DNA by specific complex formation.

1988 • 60 citations

Comparison of the open complexes formed by RNA polymerase at the Escherichia coli lac UV5 promoter

1987 • 49 citations

Nucleotide sequence of the promoter region of the gene cluster for proton-translocating ATPase from Escherichiacoli and identification of the active promoter

1982 • 44 citations

Visualization of the movement of the Escherichia coli RNA polymerase along the Lac UV5 promoter during the initiation of the transcription

1986 • 43 citations

Spatial arrangement of DNA-dependent RNA polymerase of Escherichia coli and DNA in the specific complex

1988 • 42 citations

Visualization of intermediary transcription states in the complex between Escherichia coli DNA‐dependent RNA polymerases and a promoter‐carrying DNA fragment using the gel retardation method

1986 • 31 citations

Processive pyrophosphorolysis of RNA by Escherichia coli RNA polymerase

1982 • 30 citations

RNA polymerase: correlation between transcript length abortive product synthesis and formation of a stable ternary complex

1982 • 21 citations

Large-scale preparation of a DNA fragment containing the strong promoter A1 of the phage T7

1987 • 15 citations

RNA Polymerase: a model for rotational translocation

1981 • 14 citations

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