Deficiency of the Hck and Src tyrosine kinases results in extreme levels of extramedullary hematopoiesis

Antibodies, a laboratory manual

1989 • 12,929 citations

Antibodies: A laboratory manual

1989 • 4,532 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

c-Fos: a Key Regulator of Osteoclast-Macrophage Lineage Determination and Bone Remodeling

1994 • 1,253 citations

Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice

1992 • 1,138 citations

Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells.

1990 • 1,028 citations

Profound block in thymocyte development in mice lacking p56lck

1992 • 965 citations

Bone and haematopoietic defects in mice lacking c-fos

1992 • 939 citations

Pleiotropic effects of a null mutation in the c-fos proto-oncogene

1992 • 643 citations

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1992 • 574 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice.

1992 • 557 citations

A Genetic Linkage Map of the Mouse: Current Applications and Future Prospects

1993 • 549 citations

Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption

1993 • 537 citations

Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells.

1991 • 512 citations

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

1992 • 503 citations

The Bone Marrow-Derived Stromal Cell Lines MC3T3-G2/PA6 and ST2 Support Osteoclast-Like Cell Differentiation in Cocultures with Mouse Spleen Cells

1989 • 501 citations

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells.

1993 • 338 citations

Osteopetrosis in Src-deficient mice is due to an autonomous defect of osteoclasts.

1993 • 331 citations

c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism.

1995 • 324 citations

Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

1994 • 317 citations

Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.

1994 • 253 citations

Myristoylation and Differential Palmitoylation of the HCK Protein-Tyrosine Kinases Govern Their Attachment to Membranes and Association with Caveolae

1995 • 237 citations

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity.

1994 • 232 citations

The Src family of tyrosine protein kinases in hemopoietic signal transduction

1992 • 221 citations

Delayed hematopoietic development in osteopetrotic (op/op) mice.

1993 • 196 citations

Preparation and characterization of a mouse osteoclast-like multinucleated cell population

1992 • 159 citations

Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn.

1994 • 148 citations

Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction.

1993 • 138 citations

Targeted disruption of the c-src protooncogene leads to osteopetrosis in mice

1991 • 85 citations

The murine mutation osteopetrosis is in the coding region of the macrophage colony-stimulating factor gene

1990 • 80 citations

Gene expression during skeletal development in three osteopetrotic rat mutations. Evidence for osteoblast abnormalities

1991 • 63 citations

Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment

1994 • 58 citations

Expression of the c-fgr and hck protein-tyrosine kinases in acute myeloid leukemic blasts is associated with early commitment and differentiation events in the monocytic and granulocytic lineages

1991 • 56 citations

Spleen stromal cell lines selectively support erythroid colony formation

1989 • 54 citations

Engagement of MHC class II molecules by staphylococcal superantigens activates src‐type protein tyrosine kinases

1994 • 54 citations

Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment.

1994 • 49 citations

The src family of tyrosine protein kinases in hemopoietic signal transduction

1993 • 42 citations

Age-related changes in extramedullary hematopoiesis in the spleen of normal and perturbed osteopetrotic (op/op) mice.

1994 • 30 citations

Abnormalities of phosphoprotein gene expression in three osteopetrotic rat mutations: Elevated mrna transcripts, protein synthesis, and accumulation in bone of mutant animals

1994 • 20 citations

Monoclonal antibodies to the amino-terminal sequence of the c-yes gene product as specific probes of its expression.

1990 • 19 citations

Spleen stromal cell lines selectively support erythroid colony formation

1989 • 7 citations

Expression of the c-fgr and hck protein-tyrosine kinases in acute myeloid leukemic blasts is associated with early commitment and differentiation events in the monocytic and granulocytic lineages

1991 • 3 citations