Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn.

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Fc Receptors

1991 • 1,220 citations

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

1990 • 647 citations

Engagement of the high-affinity IgE receptor activates src protein-related tyrosine kinases

1992 • 503 citations

Association of B Cell Antigen Receptor with Protein Tyrosine Kinase Lyn

1991 • 471 citations

Anti-immunoglobulin stimulation of B lymphocytes activates src-related protein-tyrosine kinases.

1991 • 433 citations

Requirement for association of p56lck with CD4 in antigen-specific signal transduction in T cells

1991 • 417 citations

Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor.

1994 • 367 citations

The Ick tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

1989 • 362 citations

The B Cell Antigen Receptor Complex: Association of Ig-α and Ig-β with Distinct Cytoplasmic Effectors

1992 • 307 citations

Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells.

1987 • 278 citations

The binding affinity of human IgG for its high affinity Fc receptor is determined by multiple amino acids in the CH2 domain and is modulated by the hinge region.

1991 • 261 citations

Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin.

1987 • 253 citations

Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation.

1993 • 232 citations

Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase.

1993 • 198 citations

Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain.

1992 • 184 citations

Association between B-lymphocyte membrane immunoglobulin and multiple members of the Src family of protein tyrosine kinases.

1992 • 181 citations

Association of the high-affinity receptor for IgG (Fc gamma RI) with the gamma subunit of the IgE receptor.

1993 • 176 citations

Epidermal growth factor stimulates the phosphorylation of synthetic tyrosine-containing peptides by A431 cell membranes.

1982 • 166 citations

Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminus.

1991 • 165 citations

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn.

1992 • 151 citations

Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells.

1992 • 145 citations

Human Fc gamma RII, in the absence of other Fc gamma receptors, mediates a phagocytic signal.

1991 • 140 citations

Involvement of p72syk, a protein-tyrosine kinase, in Fc gamma receptor signaling

1993 • 137 citations

Hck tyrosine kinase activity modulates tumor necrosis factor production by murine macrophages.

1993 • 121 citations

Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization.

1991 • 121 citations

Lipopolysaccharide- and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages.

1992 • 115 citations

Physical association between the high-affinity IgG receptor (Fc gamma RI) and the gamma subunit of the high-affinity IgE receptor (Fc epsilon RI gamma).

1993 • 95 citations

Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products.

1992 • 93 citations

Tyrosine phosphorylation provides an early and requisite signal for the activation of natural killer cell cytotoxic function.

1991 • 93 citations

An Immunodeficiency Characterized by Defective Signal Transduction in T Lymphocytes

1989 • 88 citations

Protein tyrosine phosphorylation induced via the IgG receptors Fc gamma Ri and Fc gamma RII in the human monocytic cell line THP-1.

1992 • 75 citations

Association of all three types of Fc gamma R (CD64, CD32, and CD16) with a gamma-chain homodimer in cultured human monocytes.

1993 • 74 citations

Signal transduction by the SRC family of tyrosine protein kinases in hemopoietic cells.

1991 • 64 citations

Identification of a Human Gene (HCK) that Encodes a Protein-Tyrosine Kinase and is Expressed in Hemopoietic Cells

1987 • 63 citations

Novel Protein-Tyrosine Kinase Gene (hck) Preferentially Expressed in Cells of Hematopoietic Origin

1987 • 62 citations

The gamma chain of the high-affinity receptor for IgE is a major functional subunit of the T-cell antigen receptor complex in gamma delta T lymphocytes.

1993 • 61 citations

Engagement of MHC class II molecules by staphylococcal superantigens activates src‐type protein tyrosine kinases

1994 • 54 citations

Association between B-Lymphocyte Membrane Immunoglobulin and Multiple Members of the Src Family of Protein Tyrosine Kinases

1992 • 52 citations

Neutrophil activation through high-affinity Fc gamma receptor using a monomeric antibody with unique properties.

1991 • 50 citations

Hematopoietic Cells Express Two Forms of lyn Kinase Differing by 21 Amino Acids in the Amino Terminus

1991 • 39 citations

Association of the human Fc epsilon RI gamma subunit with novel cell surface polypeptides.

1992 • 30 citations

Differential responses of p56lyn and p53lyn, products of alternatively spliced lyn mRNA, on stimulation of B-cell antigen receptor.

1991 • 25 citations

The cDNAs encoding two forms of the LYN protein tyrosine kinase are expressed in rat mast cells and human myeloid cells

1994 • 14 citations