The Molecular Biology of Progesterone Receptors: Why Are There Two Isoforms?

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

1993 • 749 citations

Steroid Hormone Receptors: Interaction with Deoxyribonucleic Acid and Transcription Factors*

1993 • 724 citations

Solution Structure of the Glucocorticoid Receptor DNA-Binding Domain

1990 • 609 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Predicting Response to Endocrine Therapy in Human Breast Cancer: A Hypothesis

1975 • 570 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

Preferential Heterodimer Formation by Isolated Leucine Zippers from Fos and Jun

1989 • 469 citations

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors.

1993 • 330 citations

A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform.

1994 • 313 citations

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function

1993 • 304 citations

The hormone response element of the mouse mammary tumour virus DNA mediates the progestin and androgen induction of transcription in the proviral long terminal repeat region.

1987 • 275 citations

Regulatory crosstalk at composite response elements

1991 • 261 citations

New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.

1994 • 214 citations

RU486 exerts antiestrogenic activities through a novel progesterone receptor A form-mediated mechanism.

1994 • 214 citations

The Molecular Biology of RU486. Is There a Role for Antiprogestins in the Treatment of Breast Cancer?*

1992 • 212 citations

Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP

1993 • 181 citations

A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform

1994 • 145 citations

Transcriptional inhibition by a glucocorticoid receptor-β-galactosidase fusion protein

1988 • 129 citations

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors [published erratum appears in Mol Endocrinol 1993 Nov;7(11):1378]

1993 • 118 citations

Functional Interference between the Ubiquitous and Constitutive Octamer Transcription Factor 1 (OTF-1) and the Glucocorticoid Receptor by Direct Protein-Protein Interaction Involving the Homeo Subdomain of OTF-1

1992 • 97 citations

Cyclic AMP-dependent protein kinase promotes glucocorticoid receptor function.

1986 • 97 citations

Antiprogestins prevent progesterone receptor binding to hormone responsive elements in vivo.

1994 • 60 citations

Inhibition of Gene Expression by Steroid Hormone ReceptorsViaa Negative Glucocorticoid Response Element: Evidence for the Involvement of DNA-Binding and Agonistic Effects of the Antiglucocorticoid/Antiprogestin RU486

1993 • 56 citations

Functional interference between the ubiquitous and constitutive octamer transcription factor 1 (OTF-1) and the glucocorticoid receptor by direct protein-protein interaction involving the homeo subdomain of OTF-1.

1992 • 51 citations

The leucine zippers of c-fos and c-jun for progesterone receptor dimerization: A-dominance in the A/B heterodimer

1994 • 42 citations