The leucine zippers of c-fos and c-jun for progesterone receptor dimerization: A-dominance in the A/B heterodimer

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.

1990 • 1,510 citations

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

1991 • 1,501 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

1988 • 1,084 citations

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

1993 • 749 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

Leucine Repeats and an Adjacent DNA Binding Domain Mediate the Formation of Functional cFos-cJun Heterodimers

1989 • 676 citations

Negative effect of the transcriptional activator GAL4

1988 • 672 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

Preferential Heterodimer Formation by Isolated Leucine Zippers from Fos and Jun

1989 • 469 citations

Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing

1989 • 437 citations

The N-terminal region of the chicken progesterone receptor specifies target gene activation

1988 • 425 citations

Evidence That the 90-kDa Heat Shock Protein Is Necessary for the Steroid Binding Conformation of the L Cell Glucocorticoid Receptor

1989 • 394 citations

Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation.

1992 • 363 citations

Agonistic and antagonistic activities of RU486 on the functions of the human progesterone receptor.

1990 • 333 citations

Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors.

1993 • 330 citations

A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform.

1994 • 313 citations

The Athb-1 and −2 HD-Zip domains homodimerize forming complexes of different DNA binding specificities.

1993 • 259 citations

In SituPhotolinked Nuclear Progesterone Receptors of Human Breast Cancer Cells: Subunit Molecular Weights after Transformation and Translocation*

1983 • 238 citations

RU486 exerts antiestrogenic activities through a novel progesterone receptor A form-mediated mechanism.

1994 • 214 citations

Binding of heat shock proteins to the avian progesterone receptor.

1989 • 192 citations

Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP

1993 • 181 citations

A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms.

1992 • 171 citations

Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies

1987 • 162 citations

The human progesterone receptor A-form functions as a transcriptional modulator of mineralocorticoid receptor transcriptional acitivity

1994 • 153 citations

Human Progesterone Receptor Complexed with the Antagonist RU 486 Binds to Hormone Response Elements in a Structurally Altered Form

1989 • 138 citations

Dimerization of mammalian progesterone receptors occurs in the absence of DNA and is related to the release of the 90-kDa heat shock protein.

1991 • 133 citations

Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription

1990 • 110 citations

Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding.

1992 • 108 citations

Phosphotryptic Peptide Analysis of Human Progesterone Receptors

1989 • 95 citations

Hormone-dependent Covalent Modification and Processing of Human Progesterone Receptors in the Nucleus

1985 • 70 citations

Analysis of dimerization and DNA binding functions in Fos and Jun by domain-swapping: involvement of residues outside the leucine zipper/basic region.

1990 • 67 citations

Synthesis of Human Progesterone Receptors in T47D Cells

1989 • 64 citations

Nonfunctioning Progesterone Receptors in the Developed Oviducts from Estrogen-Withdrawn Immature Chicks and in Aged Nonlaying Hens*

1982 • 60 citations

Circannual Rhythms in Steroid Receptor Concentration and Nuclear Binding in the Chick Oviduct*

1980 • 57 citations

Effects of the steroid antagonist RU486 on dimerization of the human progesterone receptor

1992 • 52 citations

Reconstitution of ligand-mediated glucocorticoid receptor activity by trans-acting functional domains.

1993 • 23 citations

Progesterone receptor structure and protease activity in primary human endometrial carcinoma.

1988 • 22 citations

Epitope mapping of the anti-human progesterone receptor monoclonal antibody, AB-52

1991 • 10 citations