Putative mechanisms for vascular damage by homocysteine

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1995 • 12,086 citations

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease

1995 • 3,645 citations

A Prospective Study of Plasma Homocyst(e)ine and Risk of Myocardial Infarction in US Physicians

1992 • 1,686 citations

Nitric Oxide Is Responsible for Flow-Dependent Dilatation of Human Peripheral Conduit Arteries In Vivo

1995 • 1,632 citations

The natural history of homocystinuria due to cystathionine beta-synthase deficiency.

1985 • 1,251 citations

Disorders of transsulfuration

1989 • 1,053 citations

Hyperhomocysteinemia as a Risk Factor for Deep-Vein Thrombosis

1996 • 1,034 citations

Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis.

1976 • 933 citations

Adverse vascular effects of homocysteine are modulated by endothelium-derived relaxing factor and related oxides of nitrogen.

1993 • 865 citations

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.

1986 • 826 citations

Serum Total Homocysteine and Coronary Heart Disease

1995 • 668 citations

Vascular dysfunction in monkeys with diet-induced hyperhomocyst(e)inemia.

1996 • 503 citations

Homocysteine-induced endothelial cell injury in vitro: A model for the study of vascular injury

1980 • 489 citations

Atherosclerosis or lipoprotein-induced endothelial dysfunction. Potential mechanisms underlying reduction in EDRF/nitric oxide activity.

1992 • 457 citations

Homocysteine theory of arteriosclerosis

1975 • 338 citations

Coexistence of Hereditary Homocystinuria and Factor V Leiden — Effect on Thrombosis

1996 • 266 citations

Homocysteine and other sulfhydryl compounds enhance the binding of lipoprotein(a) to fibrin: a potential biochemical link between thrombosis, atherogenesis, and sulfhydryl compound metabolism.

1992 • 265 citations

Impaired endothelial function occurs in the systemic arteries of children with homozygous homocystinuria but not in their heterozygous parents

1993 • 259 citations

Homocysteinemia: Association of a metabolic disorder with vascular disease and thrombosis

1993 • 249 citations

Endothelial Dysfunction in Atherosclerosis

1996 • 243 citations

Pathological findings in homocystinuria

1964 • 223 citations

Evidence for McKusick's hypothesis of deficient collagen cross-linking in patients with homocystinuria

1996 • 212 citations

Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells.

1996 • 207 citations

Homocysteine metabolism and the oxidative modification of proteins and lipids

1993 • 164 citations

Homocysteine mediated endothelial cell toxicity and its amelioration

1996 • 152 citations

Human arterial endothelial cell detachment in vitro: its promotion by homocysteine and cysteine

1991 • 113 citations

Lipid peroxidation and susceptibility of low‐density lipoprotein to in vitro oxidation in hyperhomocysteinaemia

1995 • 109 citations

Inhibition by sulfhydryl compounds of vascular relaxation induced by nitric oxide and endothelium-derived relaxing factor.

1993 • 85 citations

Circulating lipid hydroperoxide levels in human hyperhomocysteinemia. Relevance to development of arteriosclerosis.

1993 • 81 citations

Endothelium-Derived Relaxing Factor Modulates the Atherothrombogenic Effects of Homocysteine

1992 • 46 citations