Zinc metallochemistry in biochemistry

Electrochemical Photolysis of Water at a Semiconductor Electrode

1972 • 30,988 citations

The biochemical basis of zinc physiology

1993 • 2,967 citations

Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å

1991 • 2,034 citations

Zinc coordination, function, and structure of zinc enzymes and other proteins

1990 • 1,731 citations

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

1991 • 1,501 citations

A CADMIUM PROTEIN FROM EQUINE KIDNEY CORTEX

1957 • 1,295 citations

Reaction mechanism of alkaline phosphatase based on crystal structures

1991 • 930 citations

[69] Overview of metallothionein

1991 • 793 citations

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc‐binding environments (HEXXHXXGXXH and Met‐turn) and topologies and should be grouped into a common family, the ‘metzincins’

1993 • 729 citations

3 Alcohol Dehydrogenases

1975 • 706 citations

Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers

1993 • 679 citations

DNA recognition by GAL4: structure of a protein-DNA complex

1992 • 664 citations

Metalloenzymes: the entatic nature of their active sites.

1968 • 625 citations

How Cells Respond to Stress

1993 • 481 citations

Three-dimensional structure of the alkaline protease of Pseudomonas aeruginosa: a two-domain protein with a calcium binding parallel beta roll motif.

1993 • 468 citations

Solution structure of the DMA-binding domain of the oestrogen receptor

1990 • 458 citations

Crystal Structure of Human Carbonic Anhydrase C

1972 • 446 citations

Active-site zinc ligands and activated H2O of zinc enzymes.

1990 • 432 citations

Carboxypeptidase A: A Protein and an Enzyme

1971 • 396 citations

Zinc: biological functions and coordination motifs

1993 • 395 citations

Cytidine Deaminase. The 2·3 Å Crystal Structure of an Enzyme: Transition-state Analog Complex

1994 • 378 citations

Xenopus transcription factor A requires zinc for binding to the 5 S RNA gene.

1983 • 356 citations

Structure of the Catalytic Domain of Fibroblast Collagenase Complexed with an Inhibitor

1994 • 321 citations

An Exploratory Study of Homeschooling in Kansas

1993 • 317 citations

Three-dimensional Structure of Thermolysin

1972 • 292 citations

Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains.

1991 • 268 citations

Crystal structure of Penicillium citrinum P1 nuclease at 2.8 A resolution.

1991 • 256 citations

Crystal structure of human erythrocyte carbonic anhydrase B. Three-dimensional structure at a nominal 2.2-A resolution.

1975 • 245 citations

New perspective on zinc biochemistry: Cocatalytic sites in multi-zinc enzymes

1993 • 238 citations

Crystal and molecular structures of native and CTP-liganded aspartate carbamoyltransferase from Escherichia coli

1982 • 227 citations

Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.

1992 • 225 citations

First structure of a snake venom metalloproteinase: a prototype for matrix metalloproteinases/collagenases.

1993 • 215 citations

Structure determination and refinement of bovine lens leucine aminopeptidase and its complex with bestatin

1992 • 207 citations

Zinc transfer from transcription factor IIIA fingers to thionein clusters.

1991 • 204 citations

Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution.

1991 • 201 citations

Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution.

1991 • 177 citations

[3] Cobalt as probe and label of proteins

1993 • 175 citations

An unusual active site identified in a family of zinc metalloendopeptidases.

1992 • 158 citations

Cocatalytic zinc motifs in enzyme catalysis.

1993 • 140 citations

Refined 1·8 Å X-ray Crystal Structure of Astacin, a Zinc-endopeptidase from the Crayfish Astacus astacus L.

1993 • 138 citations

Zinc Fingers

1993 • 137 citations

Zinc and gene expression

1981 • 133 citations

Leukotriene A4 hydrolase: An epoxide hydrolase with peptidase activity

1990 • 133 citations

Structure of the DNA-binding domain of zinc GAL4

1992 • 127 citations

Solution structure of the DNA-binding domain of Cd2-GAL4 from S. cerevisiae

1992 • 123 citations

Structure of a Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase at 2.5 Å resolution

1982 • 123 citations

Leukotriene A4 hydrolase: A zinc metalloenzyme

1990 • 122 citations

Structure of carboxypeptidase B at 2.8 Å resolution

1976 • 121 citations

A pre-transition-state mimic of an enzyme: x-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water

1993 • 121 citations

Crystal structure of neutral protease from Bacillus cereus refined at 3.0A˚resolution and comparison with the homologous but more thermostable enzyme thermolysin

1988 • 117 citations

Leukotriene A4 hydrolase: determination of the three zinc-binding ligands by site-directed mutagenesis and zinc analysis.

1991 • 111 citations

Metal ion homeostasis: Molecular biology and chemistry

1988 • 110 citations

An X-ray-crystallographic study of β-lactamase II from Bacillus cereus at 0.35 nm resolution

1987 • 102 citations

Crystal Structure of Phospholipase C from Bacillus cereus Complexed with a Substrate Analog

1993 • 91 citations

Short and long spacer sequences and other structural features of zinc binding sites in zinc enzymes

1989 • 78 citations

Functional zinc-binding motifs in enzymes and DNA-binding proteins

1992 • 70 citations

Fluorescent oligopeptide substrates for kinetic characterization of the specificity of Astacus protease

1990 • 69 citations

Proton NMR studies of the glucocorticoid receptor DNA-binding domain: sequential assignments and identification of secondary structure elements

1990 • 65 citations

Cadmium-113 NMR studies of reconstituted seven-cadmium metallothionein: evidence for structural flexibility

1985 • 55 citations

Conversion of a magnesium binding site into a zinc binding site by a single amino acid substitution in Escherichia coli alkaline phosphatase.

1993 • 51 citations

Conversion of a magnesium binding site into a zinc binding site by a single amino acid substitution in Escherichia coli alkaline phosphatase.

1993 • 51 citations

Active zinc binding sites of zinc metalloenzymes.

1992 • 49 citations

Cadmium-113 NMR studies of the DNA binding domain of the mammalian glucocorticoid receptor

1990 • 47 citations

Zinc biochemistry in normal and neoplastic growth processes

1977 • 45 citations

Sequential assignments of the proton NMR resonances of zinc(II)2 and cadmium-113(II)2 derivatives of the DNA-binding domain of the GAL4 transcription factor reveal a novel structural motif for specific DNA recognition

1991 • 36 citations

Zinc Content of Promatrilysin, Matrilysin and the Stromelysin Catalytic Domain

1994 • 25 citations

Initiation, processing and termination of ribosomal RNA from a hybrid 5 S ribosomal RNA gene in a plasmid

1983 • 24 citations

Polypeptide—metal cluster connectivities in Cd(II) GAL4

1991 • 23 citations

Identification of the metal coordinating residues in the DNA binding domain of the glucocorticoid receptor by ¹¹³Cd‐¹H heteronuclear NMR spectroscopy

1991 • 16 citations

The Role of Zinc in Biochemical Processes

1979 • 15 citations

[26] Detecting metal-metal interactions and measuring distances between metal centers in metalloproteins

1993 • 10 citations

A Synthetic Approach to Analysis of the Structural Zinc Site of Alcohol Dehydrogenase

1993 • 3 citations