The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants.
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References (69)
A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
1976 • 225,752 citations
Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
1973 • 12,522 citations
A simple and very efficient method for generating cDNA libraries
1983 • 4,606 citations
International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).
1994 • 2,935 citations
Current protocols in molecular biology
1988 • 2,473 citations
A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model.
1993 • 1,213 citations
Primary Structure And Functional Expression of the 5HT 3 Receptor, A Serotonin-gated Ion Channel
1991 • 976 citations
A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.
1983 • 933 citations
Sequence Alignment of the G-Protein Coupled Receptor Superfamily
1992 • 847 citations
Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs
1985 • 845 citations
[71] Use of eukaryotic expression technology in the functional analysis of cloned genes
1987 • 834 citations
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 • 691 citations
A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms
1993 • 682 citations
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
1993 • 607 citations
Palmitoylation of the human β2-adrenergic receptor
1989 • 599 citations
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor
1988 • 594 citations
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
1993 • 588 citations
A proposed new nomenclature for 5-HT receptors
1993 • 551 citations
Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity
1993 • 546 citations
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
1993 • 512 citations
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
1993 • 510 citations
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
1987 • 509 citations
Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine1A receptor gene.
1990 • 444 citations
A nonclassical 5-hydroxytryptamine receptor positively coupled with adenylate cyclase in the central nervous system.
1988 • 435 citations
Structure and functional expression of cloned rat serotonin 5HT-2 receptor.
1988 • 381 citations
Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor.
1994 • 357 citations
Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.
1992 • 293 citations
Development of a radioligand binding assay for 5‐HT4 receptors in guinea‐pig and rat brain
1993 • 285 citations
Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.
1993 • 281 citations
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 • 280 citations
Cloning and expression of a novel mouse somatostatin receptor (SSTR2B)
1992 • 270 citations
Pharmacological characterization of a neuronal receptor for 5-hydroxytryptamine in guinea pig ileum with properties similar to the 5-hydroxytryptamine receptor.
1990 • 260 citations
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
1993 • 246 citations
The 5-HT4 receptor: a place in the sun
1992 • 240 citations
Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain.
1986 • 226 citations
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
1991 • 225 citations
Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers.
1992 • 221 citations
Molecular cloning and characterization of a rat brain cDNA encoding a 5-hydroxytryptamine1B receptor.
1991 • 216 citations
Cloning and expression of an adenylyl cyclase localized to the corpus striatum
1993 • 206 citations
5-Hydroxytryptamine4 receptors mediate relaxation of the rat oesophageal tunica muscularis mucosae
1991 • 205 citations
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.
1993 • 199 citations
Pharmacological characterization of 5-hydroxytryptamine4(5-HT4) receptors positively coupled to adenylate cyclase in adult guinea pig hippocampal membranes: effect of substituted benzamide derivatives.
1990 • 196 citations
A 5‐hydroxytryptamine receptor in human atrium
1990 • 193 citations
Cloning and functional characterization of the rat stomach fundus serotonin receptor.
1992 • 192 citations
Molecular cloning, functional expression, and pharmacological characterization of a novel serotonin receptor (5-hydroxytryptamine2F) from rat stomach fundus.
1992 • 181 citations
Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain.
1993 • 179 citations
Characterization of the human 5-hydroxytryptamine1B receptor.
1992 • 172 citations
Serotonin: Molecular Biology, Receptors and Functional Effects
1991 • 170 citations
The rat 5-hydroxytryptamine1B receptor is the species homologue of the human 5-hydroxytryptamine1D beta receptor.
1992 • 167 citations
Serotonin-induced stimulation of cortisol secretion from human adrenocortical tissue is mediated through activation of a serotonin4 receptor subtype
1992 • 155 citations
Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.
1992 • 153 citations
Human serotonin1B receptor expression in Sf9 cells: Phosphorylation, palmitoylation, and adenylyl cyclase inhibition
1993 • 146 citations
The 5‐HT4 Receptor
1993 • 145 citations
The two isoforms of the mouse somatostatin receptor (mSSTR2A and mSSTR2B) differ m coupling efficiency to adenylate cyclase and in agonist‐induced receptor desensitization
1993 • 132 citations
Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs.
1993 • 131 citations
Pharmacological characterization of two 5-hydroxytryptamine receptors coupled to adenylate cyclase in guinea pig hippocampal membranes.
1987 • 124 citations
[3H]-GR113808 labels 5-HT4 receptors in the human and guinea-pig brain
1993 • 110 citations
Isolation of a mouse “5HT1E-like” serotonin receptor expressed predominantly in hippocampus.
1992 • 108 citations
Inhibition of cloned adenylyl cyclases by mutant-activated Gi-alpha and specific suppression of type 2 adenylyl cyclase inhibition by phorbol ester treatment
1993 • 108 citations
Differential expression of the beta-adrenergic receptor modifies agonist stimulation of adenylyl cyclase: a quantitative evaluation.
1994 • 107 citations
A human serotonin 1D receptor variant (5HT1D beta) encoded by an intronless gene on chromosome 6.
1992 • 95 citations
Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes.
1993 • 93 citations
BRL 24924: a potent agonist at a non-classical 5-HT receptor positively coupled with adenylate cyclase in colliculi neurons
1989 • 84 citations
Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor.
1992 • 81 citations
Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors.
1988 • 81 citations
The effects of SB 204070, a highly potent and selective 5‐HT4 receptor antagonist, on guinea‐pig distal colon
1994 • 73 citations
Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase
1992 • 72 citations
The Infectivity of Polyoma Virus DNA for Mouse Embryo Cells in the Presence of Diethylaminoethyl-dextran
1968 • 57 citations
Pharmacological analysis of 5‐hydroxytryptamine effects on electrically stimulated human isolated urinary bladder
1991 • 55 citations
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